scholarly journals HLA-G is expressed by the glandular epithelium of peritoneal endometriosis but not in eutopic endometrium

2005 ◽  
Vol 21 (4) ◽  
pp. 864-869 ◽  
Author(s):  
B.F. Barrier ◽  
B.S. Kendall ◽  
C.E. Ryan ◽  
K.L. Sharpe-Timms
Keyword(s):  
Glandular Epithelium ◽  
Eutopic Endometrium ◽  
Peritoneal Endometriosis

Increased Mast Cell Density in Peritoneal Endometriosis Compared with Eutopic Endometrium with Endometriosis

1998 ◽  
Vol 40 (4) ◽  
pp. 291-294 ◽  
Author(s):  
SACHIKO MATSUZAKI ◽  
MICHEL CANIS ◽  
CLAUDE DARCHA ◽  
TAKAO FUKAYA ◽  
AKIRA YAJIMA ◽  
...  
Keyword(s):  
Mast Cell ◽  
Cell Density ◽  
Eutopic Endometrium ◽  
Mast Cell Density ◽  
Peritoneal Endometriosis

ADENOMYOSIS AND PERITONEAL ENDOMETRIOSIS EXHIBIT A CLONAL RELATIONSHIP WITH EUTOPIC ENDOMETRIUM

2020 ◽  
Vol 114 (3) ◽  
pp. e213
Author(s):  
Maria Facadio Antero ◽  
Lihong Li ◽  
Tiffany Chu ◽  
Leslie Cope ◽  
Tian-Li Wang ◽  
...  
Keyword(s):  
Eutopic Endometrium ◽  
Clonal Relationship ◽  
Peritoneal Endometriosis

scholarly journals Low Expression of STING Promoted Endometrial Stromal Cells Invasion and Migration Via STING/IRF3/IFNb1 Pathway in Endometriosis Eutopic Endometrium

2021 ◽  
Author(s):  
zhen xu ◽  
hen zhao ◽  
caixin yue ◽  
lixia zhang ◽  
muzi li ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Stromal Cells ◽  
Chronic Inflammatory Disease ◽  
Glandular Epithelium ◽  
Normal Endometrium ◽  
Endometrial Stromal Cells ◽  
Eutopic Endometrium ◽  
Invasion And Migration ◽  
And Migration ◽  
Low Expression

Abstract Background: Recent studies have confirmed that endometriosis is a chronic inflammatory disease. In our previous work, we found that STING (stimulator of interferon genes) was differentially expressed in eutopic endometrium and controlled endometrium by proteomics.Method: we used the 11 pairs of samples to verify STING expression by WB and IHC experiments. We detected cells proliferation by EdU assays, cells invasion and migration by Transwell assays. The effect of signaling pathway in HESC was detected by WB and Elisa expreriments.Results: STING was significantly lower expressed in eutopic endometrium of endometriosis, while IHC results showed that STING was expressed in both stroma and glandular epithelium of normal endometrium, but in endometriosis, STING was mainly expressed in the stroma of eutopic endometrium, and mainly in glandular epithelium of ectopic endometrium. Further study on the role of STING on endometrial stromal cells showed that low expression of STING could promote the HESC proliferation by EdU experiments, invasion and migration by Transwell experiments. The effect of STING/IRF3/IFNb1 signaling pathway in HESC with low expression of STING was also reduced, mainly showed the decreased expression of phosphorylated IRF3 and TBK1, and the decreased secretion of IFNb1. In order to further study the effect of IFNb1, secreted by STING/ IRF3/IFNb1 signaling pathway, on stromal cells, we added exogenous IFNb1 to the HESC with low expression of STING, and found that IFNb1 could reverse the invasion and migration function of stromal cells, but little effect on cell proliferation.Conclusions: We clarified that STING expressed mainly in stromal tissues and lower in endometriosis eutopic endometrium compared to normal endometrium. Low expressed STING promoted stromal cells invasion and migration via STING/IRF3/IFNb1 signaling pathway.

Expression of GLUT-1 in human eutopic endometrium, in peritoneal endometriotic lesions, and in deep-infiltrating endometriosis

2011 ◽  
Vol 71 (10) ◽  
Author(s):  
C von Kleinsorgen ◽  
W von Zglienicki ◽  
U Thiel-Moder ◽  
G Niedobitek-Kreuter ◽  
S Mechsner ◽  
...  
Keyword(s):  
Deep Infiltrating Endometriosis ◽  
Eutopic Endometrium ◽  
Glut 1 ◽  
Infiltrating Endometriosis
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