scholarly journals Elevation of serum testosterone and free testosterone after embolization of the internal spermatic vein for the treatment of varicocele in infertile men

2004 ◽  
Vol 19 (10) ◽  
pp. 2303-2306 ◽  
Author(s):  
Yigal Gat ◽  
Michael Gornish ◽  
Alexander Belenky ◽  
Gil N. Bachar
Urology ◽  
2011 ◽  
Vol 78 (3) ◽  
pp. S232
Author(s):  
P. Sountoulides ◽  
S. Gravas ◽  
D. Kikidakis ◽  
A. Theodosiou ◽  
K. Paschalidis ◽  
...  

2006 ◽  
Vol 8 (4) ◽  
pp. 451-454 ◽  
Author(s):  
Taymour Mostafa ◽  
Tarek H. Anis ◽  
Sherif Ghazi ◽  
Abdel Rahman El-Nashar ◽  
Hager Imam ◽  
...  

1980 ◽  
Vol 52 (1) ◽  
pp. 50-56 ◽  
Author(s):  
A. V. HIRSH ◽  
K. M. CAMERON ◽  
J. P. TYLER ◽  
J. SIMPSON ◽  
J. P. PRYOR

1988 ◽  
Vol 117 (2) ◽  
pp. 268-272 ◽  
Author(s):  
Akihiko Okuyama ◽  
Masahiro Nakamura ◽  
Mikio Namiki ◽  
Masami Takeyama ◽  
Hideki Fujioka ◽  
...  

Abstract. In order to investigate the secretion of renin from the Leydig cells of human testis, plasma renin activity (PRA) in left internal spermatic vein (ISV) and cubital vein (CV) was measured at the time of surgical repair of varicocele in 19 patients aged from 21 to 39 years. Ten of them were given a single im administration of hCG (10000 IU/m2) 4 days before the operation, whereas the remaining nine were not treated. Although mean PRA levels in CV in treated and non-treated groups were similar (1.25 ± 0.45 and 1.14 ± 0.38 nmol/l per h, respectively), mean PRA level of ISV in the treated group (3.52 ± 0.76 nmol/l per h) was significantly higher than that in the non-treated group (1.30 ± 0.32 nmol/l per h) (P < 0.01); serum testosterone levels in the same ISV were also much higher in the treated than in non-treated group (P < 0.001). These data show the following results; 1) under basal conditions, no release of renin from Leydig cells into testicular blood flow could be observed; 2) after treatment with hCG, the secretion of renin into the ISV seemed to be demonstrable. The present results suggest for the first time the secretion of hCG-induced renin from the human testis in vivo.


1997 ◽  
pp. 670-674 ◽  
Author(s):  
Y Sahin ◽  
F Kelestimur

OBJECTIVE: To determine the frequency of late-onset adrenal hyperplasia (LOCAH) due to 21-hydroxylase (21-OH) and 11 beta-hydroxylase (11 beta-OH) deficiency in women with clinical and biochemical features of polycystic ovary syndrome (PCOS). DESIGN: Eighty-three consecutively selected women with PCOS and eighteen normal women were included in the study. METHODS: Ultrasound, clinical and hormonal parameters were used to define PCOS. Basal FSH, LH, testosterone, free testosterone, androstenedione, dehydroepiandrosterone sulfate (DHEA-S), sex hormone-binding globulin (SHBG) and cortisol levels were measured. Serum 17-hydroxyprogesterone (17-OHP) and 11-deoxycortisol (11-DOC) levels were also measured before, 30 and 60 min after a single bolus injection of 0.25 mg ACTH (1-24) at 0900 h during the mid-follicular phase of the cycle. ACTH-stimulated 17-OHP levels > 30 nmol/l were considered as the criteria of 21-OH deficiency. The diagnosis 11 beta-OH deficiency was made if the adrenal 11-DOC response to ACTH stimulation exceeded threefold the 95th percentile of controls. RESULTS: Basal serum testosterone, free testosterone, androstenedione, DHEA-S, cortisol and 11-DOC levels were significantly higher in PCOS than in control subjects. ACTH-stimulated 17-OHP (P < 0.05) and 11-DOC (P < 0.0005) levels were found to be significantly higher in patients with PCOS than in controls. Seven (8.4%) patients had an 11-DOC response to ACTH higher than threefold the 95th percentile of controls, while no patients showed evidence of 21-OH deficiency. CONCLUSIONS: We have found that 8.4% of the women with clinical and biochemical features of PCOS could be presumed to have 11 beta-OH deficiency. No patients among the women with PCOS showed evidence of 21-OH deficiency. 11 beta-OH deficiency is unexpectedly more common than 21-OH deficiency in women with PCOS.


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