scholarly journals Circulating cell-free fetal DNA in maternal serum appears to originate from cyto- and syncytio-trophoblastic cells. Case report

2004 ◽  
Vol 19 (3) ◽  
pp. 723-724 ◽  
Author(s):  
E. Flori
Keyword(s):  
Case Report ◽  
Maternal Serum ◽  
Fetal Dna ◽  
Trophoblastic Cells ◽  
Cell Free Fetal Dna

Down syndrome and cell-free fetal DNA in archived maternal serum

2002 ◽  
Vol 187 (5) ◽  
pp. 1217-1221 ◽  
Author(s):  
Thomas Lee ◽  
Erik S. LeShane ◽  
Geralyn M. Messerlian ◽  
Jacob A. Canick ◽  
Antonio Farina ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Maternal Serum ◽  
Fetal Dna ◽  
Cell Free Fetal Dna

scholarly journals Applications of Cell-Free Fetal DNA in Maternal Serum

2012 ◽  
Vol 3 (2) ◽  
pp. 33-39 ◽  
Author(s):  
Saeid Ghorbian
Keyword(s):  
Prenatal Diagnosis ◽  
Single Gene ◽  
Late Pregnancy ◽  
Maternal Serum ◽  
Maternal Circulation ◽  
Fetal Dna ◽  
Noninvasive Prenatal Diagnosis ◽  
Cell Free Fetal Dna ◽  
Paternity Determination ◽  
Free Circulating Dna

ABSTRACT Cell-free fetal DNA (cffDNA) is available in the maternal circulation throughout pregnancy and can be used for noninvasive prenatal diagnosis including, determination of fetal sex, identification of specific single gene disorders, typing of fetal blood groups (RhD), paternity determination and potentially routine use for Down's syndrome (DS) testing of all pregnancies. I searched published literature on the PubMed and databases on Scopus interface systematically using keyword's cffDNA, noninvasive diagnosis, fetal DNA in the maternal serum. Reference lists from the papers were also searched. cffDNA representing only 3% of the total cell-free circulating DNA in early and rising to 12% in late pregnancy, clinical investigations has already demonstrated the potential advantage, such as improving safety, earlier diagnosis and comparative ease of testing using cffDNA technology. The discovery of cffDNA circulating in the maternal serum has opened the door to noninvasive prenatal diagnosis testing with novel clinical implications. How to cite this article Ghorbian S. Applications of Cell-Free Fetal DNA in Maternal Serum. Int J Infertility Fetal Med 2012;3(2):33-39.

Fraction of cell-free fetal DNA in the maternal serum as a predictor of abnormal placental invasion-a pilot study

2013 ◽  
Vol 33 (11) ◽  
pp. 1050-1053 ◽  
Author(s):  
Amber Samuel ◽  
Clarissa Bonanno ◽  
Arnold Oliphant ◽  
Annette Batey ◽  
Jason D. Wright
Keyword(s):  
Pilot Study ◽  
Maternal Serum ◽  
Fetal Dna ◽  
Cell Free Fetal Dna ◽  
Placental Invasion

22 Fetal down syndrome is associated with increased cell-free fetal DNA levels in archived maternal serum samples

2001 ◽  
Vol 185 (6) ◽  
pp. S79 ◽  
Author(s):  
Thomas Lee ◽  
Erik Leshane ◽  
Geralyn Messerlian ◽  
Jacob Canick ◽  
Marshall Carpenter ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Maternal Serum ◽  
Serum Samples ◽  
Fetal Dna ◽  
Cell Free Fetal Dna

Cell-free fetal DNA in the maternal serum and plasma: current and evolving applications

2009 ◽  
Vol 21 (2) ◽  
pp. 175-179 ◽  
Author(s):  
Neil D Avent ◽  
Tracey E Madgett ◽  
Deborah G Maddocks ◽  
Peter W Soothill
Keyword(s):  
Maternal Serum ◽  
Plasma Current ◽  
Fetal Dna ◽  
Cell Free Fetal Dna

563: Fraction of cell-free fetal DNA in the maternal serum as a predictor of abnormal placental invasion

2013 ◽  
Vol 208 (1) ◽  
pp. S241
Author(s):  
Amber Samuel ◽  
Clarissa Bonanno ◽  
Tom Musci ◽  
Anette Batey ◽  
Jason Wright
Keyword(s):  
Maternal Serum ◽  
Fetal Dna ◽  
Cell Free Fetal Dna ◽  
Placental Invasion

179: The utility of maternal serum analyte screening in the era of cell-free fetal DNA (cffDNA)

2014 ◽  
Vol 210 (1) ◽  
pp. S101 ◽  
Author(s):  
Kimberly Herrera ◽  
Dawnette Lewis ◽  
Janelle Foroutan ◽  
Lorien King ◽  
Brianne Bimson ◽  
...  
Keyword(s):  
Maternal Serum ◽  
Fetal Dna ◽  
Cell Free Fetal Dna
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