scholarly journals Defective signaling through plexin-A1 compromises the development of the peripheral olfactory system and neuroendocrine reproductive axis in mice

2017 ◽  
Vol 26 (11) ◽  
pp. 2006-2017 ◽  
Author(s):  
Séverine Marcos ◽  
Carine Monnier ◽  
Xavier Rovira ◽  
Corinne Fouveaut ◽  
Nelly Pitteloud ◽  
...  
Keyword(s):  
Olfactory System ◽  
Reproductive Axis ◽  
Peripheral Olfactory System

scholarly journals Structural anomalies of the peripheral olfactory system in psychosis high-risk subjects

2018 ◽  
Vol 195 ◽  
pp. 197-205 ◽  
Author(s):  
Bruce I. Turetsky ◽  
Paul J. Moberg ◽  
Megan Quarmley ◽  
Erich Dress ◽  
Monica E. Calkins ◽  
...  
Keyword(s):  
High Risk ◽  
Olfactory System ◽  
Peripheral Olfactory System ◽  
Structural Anomalies

Age-related changes of the regeneration mode in the mouse peripheral olfactory system following olfactotoxic drug methimazole-induced damage

2011 ◽  
Vol 519 (11) ◽  
pp. 2154-2174 ◽  
Author(s):  
Keigo Suzukawa ◽  
Kenji Kondo ◽  
Kaori Kanaya ◽  
Takashi Sakamoto ◽  
Kenta Watanabe ◽  
...  
Keyword(s):  
Olfactory System ◽  
Age Related ◽  
Peripheral Olfactory System ◽  
Age Related Changes

scholarly journals Sensorimotor pathway controlling stopping behavior during chemotaxis in the Drosophila melanogaster larva

eLife ◽  
2018 ◽  
Vol 7 ◽  
Author(s):  
Ibrahim Tastekin ◽  
Avinash Khandelwal ◽  
David Tadres ◽  
Nico D Fessner ◽  
James W Truman ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Drosophila Melanogaster ◽  
Olfactory System ◽  
Action Selection ◽  
Pivotal Role ◽  
Motor Circuit ◽  
Mechanistic Analysis ◽  
Main Pathway ◽  
Peripheral Olfactory System ◽  
Artificial Activation

Sensory navigation results from coordinated transitions between distinct behavioral programs. During chemotaxis in the Drosophila melanogaster larva, the detection of positive odor gradients extends runs while negative gradients promote stops and turns. This algorithm represents a foundation for the control of sensory navigation across phyla. In the present work, we identified an olfactory descending neuron, PDM-DN, which plays a pivotal role in the organization of stops and turns in response to the detection of graded changes in odor concentrations. Artificial activation of this descending neuron induces deterministic stops followed by the initiation of turning maneuvers through head casts. Using electron microscopy, we reconstructed the main pathway that connects the PDM-DN neuron to the peripheral olfactory system and to the pre-motor circuit responsible for the actuation of forward peristalsis. Our results set the stage for a detailed mechanistic analysis of the sensorimotor conversion of graded olfactory inputs into action selection to perform goal-oriented navigation.

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