scholarly journals The IRF5–TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share

2014 ◽  
Vol 24 (2) ◽  
pp. 582-596 ◽  
Author(s):  
Leah C. Kottyan ◽  
Erin E. Zoller ◽  
Jessica Bene ◽  
Xiaoming Lu ◽  
Jennifer A. Kelly ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Autoimmune Disorders ◽  
Systemic Lupus

scholarly journals Autoimmune myelofibrosis: a rare haematological involvement in systemic lupus erythematosus

2019 ◽  
Vol 12 (1) ◽  
pp. bcr-2018-227520 ◽  
Author(s):  
Nabil Belfeki ◽  
Gopinath Shankarasivam ◽  
Damienne Declerck ◽  
Sylvain Diamantis
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Bone Marrow ◽  
Clinical Features ◽  
Bone Marrow Biopsy ◽  
Vitamin K ◽  
Lupus Erythematosus ◽  
Antiphospholipid Antibodies ◽  
Vitamin K Antagonists ◽  
Autoimmune Disorders ◽  
Systemic Lupus

Autoimmune myelofibrosis is a distinct clinicopathological entity that occurs with autoimmune disorders. We report the case of a 44-year-old woman admitted with pancytopenia and clinical features of systemic lupus erythematosus, Sjogren’s syndrome and antiphospholipid antibodies syndrome. Bone marrow biopsy showed decreased global cells and an increase of reticulin fibres on argentic coloration, consistent with myelofibrosis. The JAK2 V617, Myeloproliferative leukemia (MPL) and calreticulin mutations were negative. The patient’s condition improved after treatment with hydroxychloroquine, vitamin K antagonists and prednisone.

Case 54: Polyneuropathy Affecting Large and Small Fibers in Multiple Autoimmune Disorders

2019 ◽  
pp. 294-297
Author(s):  
Peter Novak
Keyword(s):  
Rheumatoid Arthritis ◽  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Orthostatic Intolerance ◽  
Autoimmune Disorders ◽  
Sjögren Syndrome ◽  
Sjogren Syndrome ◽  
Systemic Lupus ◽  
Painful Neuropathy

This patient had diagnoses of multiple autoimmune disorders including Sjögren syndrome, rheumatoid arthritis, and systemic lupus erythematosus. Sjögren syndrome can be accompanied by severe painful neuropathy and dysautonomia. Orthostatic intolerance was due to cerebral autoregulatory failure.

Systemic lupus erythematosus and other autoimmune disorders in children with Noonan syndrome

2005 ◽  
Vol 139A (3) ◽  
pp. 239-242 ◽  
Author(s):  
Elena Lopez-Rangel ◽  
Peter N. Malleson ◽  
David S. Lirenman ◽  
Benjamin Roa ◽  
Joanna Wiszniewska ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Noonan Syndrome ◽  
Autoimmune Disorders ◽  
Systemic Lupus

Autoimmune disorders in patients with idiopathic thrombotic thrombocytopenic purpura

2012 ◽  
Vol 32 (S 01) ◽  
pp. S86-S89 ◽  
Author(s):  
M.-L. John ◽  
I. Scharrer
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Celiac Disease ◽  
General Population ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Patient Group ◽  
Lupus Erythematosus ◽  
Autoimmune Disorders ◽  
Prevalence Rates ◽  
Systemic Lupus ◽  
Thrombocytopenic Purpura

Summary76 German patients suffering from thrombotic thrombocytopenic purpura (TTP) were interrogated about the prevalence of cooccurring autoimmune disorders. In order to analyze a possible association of TTP with the questioned diseases, a comparison of prevalence rates between the patient group and the general population has been made for each disease. Results: Compared to the estimated prevalence rates, the statistical analysis revealed an unexpected high occurrence of the following disorders within the patient group: Hashimoto’s thyroiditis (23.5% within the patients compared to 0.7% within the general population, p<0.001), systemic lupus erythematosus (SLE) (6.5% in patients to 0.025% in the general population, p<0.001), immune thrombocytopenic purpura (ITP) (6.3% in patients to 0.02% in the general population, p < 0.001), psoriasis (9.4% in patients to 2.5% in the general population, p = 0.005) and celiac disease (3.1% in patients to 0.2% in the general population, p = 0.007). Conclusion: These findings confirm the mentioned tendency of autoimmune diseases to co-occur in one individual and argue once more for a genetic susceptibility in idiopathic TTP as well as in autoimmune disorders.

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