scholarly journals Coding variants in TREM2 increase risk for Alzheimer's disease

2014 ◽  
Vol 23 (21) ◽  
pp. 5838-5846 ◽  
Author(s):  
Sheng Chih Jin ◽  
Bruno A. Benitez ◽  
Celeste M. Karch ◽  
Breanna Cooper ◽  
Tara Skorupa ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Increase Risk ◽  
Coding Variants

O1-04-05: NOVEL CODING VARIANTS IN TREM2 INCREASE RISK FOR ALZHEIMER'S DISEASE

2014 ◽  
Vol 10 ◽  
pp. P136-P136
Author(s):  
Carlos Cruchaga ◽  
Sheng Chih Jin ◽  
Bruno A. Benitez ◽  
Celeste Karch ◽  
Alison Goate
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Increase Risk ◽  
Coding Variants

scholarly journals Alzheimer's disease BIN1 coding variants increase intracellular Aβ levels by interfering with BACE1 recycling

2021 ◽  
pp. 101056
Author(s):  
Catarina Perdigão ◽  
Mariana A. Barata ◽  
Tatiana Burrinha ◽  
Cláudia Guimas Almeida
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Coding Variants

scholarly journals Nursing students’ knowledge about Alzheimer’s disease

2018 ◽  
Vol 8 (11) ◽  
pp. 83
Author(s):  
Lisa Kirk Wiese ◽  
Christine Lynn Williams
Keyword(s):  
Alzheimer’S Disease ◽  
Older Adults ◽  
Alzheimer's Disease ◽  
Nursing Students ◽  
Basic Knowledge ◽  
Average Life Expectancy ◽  
Essential Information ◽  
Paired Samples ◽  
Age Related ◽  
Increase Risk

Objective: Every 66 seconds a U.S. resident develops Alzheimer’s disease (AD). Future nurses will be caring for the rapidly escalating number of adults turning 65, yet information regarding nursing students’ knowledge about the age-related disease of Alzheimer’s is limited. The purpose of this study was to examine 102 Florida baccalaureate nursing students’ basic and advanced AD knowledge.Methods: A descriptive design using two AD knowledge measures and analysis using paired samples t-test were employed.Results: Although the setting was a region of the U.S. with the highest percentage of older adults, knowledge deficits regarding age-related Alzheimer’s disease were striking. Students’ basic knowledge was significantly higher than their advanced AD knowledge (t(101) = 2.28, p = .027). Only 31% of students identified that high cholesterol may increase risk. Just 20% of students correctly answered that exercise does not prevent AD. About 25% correctly responded that the average life expectancy after the onset of AD is 6-12 years. Only 2% of nursing students correctly identified that persons with AD experience stress from disease-related symptoms. Overall, less than 50% of students correctly answered any item on the measure designed for use among health care providers.Conclusions: To better prepare nursing students to care for the increasing numbers of older adults facing risk of AD, updated curricula targeting dementia-related illnesses are essential. Information is offered regarding current state of the science resources of benefit to faculty, students, and practicing nurses, such as experiential learning and Hartford Institute of Geriatric Nursing collaborative programs.

Rare Variants in PLD3 Increase Risk for Alzheimer’s Disease in Han Chinese

2018 ◽  
Vol 64 (1) ◽  
pp. 55-59 ◽  
Author(s):  
Meng-Shan Tan ◽  
Jun-Xia Zhu ◽  
Xi-Peng Cao ◽  
Jin-Tai Yu ◽  
Lan Tan
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Rare Variants ◽  
Han Chinese ◽  
Increase Risk

scholarly journals In vivo testing of the role of Alzheimer’s disease coding variants

2020 ◽  
Vol 16 (S3) ◽  
Author(s):  
Michael Sasner ◽  
Adrian L. Oblak ◽  
Dylan Garceau ◽  
Kevin P. Kotredes ◽  
Christoph Preuss ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
In Vivo Testing ◽  
Coding Variants

Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease

2014 ◽  
Vol 35 (12) ◽  
pp. 2883.e3-2883.e10 ◽  
Author(s):  
Petroula Proitsi ◽  
Michelle K. Lupton ◽  
Latha Velayudhan ◽  
Gillian Hunter ◽  
Stephen Newhouse ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Alzheimer’S Disease ◽  
Type 2 Diabetes ◽  
Alzheimer's Disease ◽  
Type 2 Diabetes Mellitus ◽  
Increased Risk ◽  
Increase Risk

scholarly journals Poor self-rated health did not increase risk of permanent nursing placement or mortality in people with mild Alzheimer’s disease

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Anni Brit Sternhagen Nielsen ◽  
Volkert Siersma ◽  
Gunhild Waldemar ◽  
Frans Boch Waldorff
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Self Rated Health ◽  
Increase Risk
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