scholarly journals GWAS of human bitter taste perception identifies new loci and reveals additional complexity of bitter taste genetics

2013 ◽  
Vol 23 (1) ◽  
pp. 259-267 ◽  
Author(s):  
Mirko Ledda ◽  
Zoltán Kutalik ◽  
Maria C. Souza Destito ◽  
Milena M. Souza ◽  
Cintia A. Cirillo ◽  
...  
Keyword(s):  
Bitter Taste ◽  
Taste Perception ◽  
Taste Genetics

Open questions in sweet, umami and bitter taste genetics

2021 ◽  
Vol 20 ◽  
pp. 174-179
Author(s):  
Davide Risso ◽  
Dennis Drayna ◽  
Sergio Tofanelli ◽  
Gabriella Morini
Keyword(s):  
Bitter Taste ◽  
Open Questions ◽  
Taste Genetics

Taste perception and expression in stomach of bitter taste receptor tas2r38 in obese and lean subjects

Appetite ◽  
2021 ◽  
pp. 105595
Author(s):  
Antonietta Robino ◽  
Natalia Rosso ◽  
Martina Guerra ◽  
Pio Corleone ◽  
Biagio Casagranda ◽  
...  
Keyword(s):  
Bitter Taste ◽  
Taste Receptor ◽  
Taste Perception ◽  
Bitter Taste Receptor

scholarly journals Human Bitter Taste Perception

2005 ◽  
Vol 30 (Supplement 1) ◽  
pp. i14-i15 ◽  
Author(s):  
W. Meyerhof
Keyword(s):  
Bitter Taste ◽  
Taste Perception

scholarly journals Genetic, Functional, and Phenotypic Diversity in TAS2R38-Mediated Bitter Taste Perception

2013 ◽  
Vol 38 (6) ◽  
pp. 475-484 ◽  
Author(s):  
M. Behrens ◽  
H. C. Gunn ◽  
P. C. M. Ramos ◽  
W. Meyerhof ◽  
S. P. Wooding
Keyword(s):  
Bitter Taste ◽  
Phenotypic Diversity ◽  
Taste Perception

scholarly journals Predators’ consumption of unpalatable prey does not vary as a function of bitter taste perception

2019 ◽  
Vol 31 (2) ◽  
pp. 383-392 ◽  
Author(s):  
Liisa Hämäläinen ◽  
Johanna Mappes ◽  
Rose Thorogood ◽  
Janne K Valkonen ◽  
Kaijamari Karttunen ◽  
...  
Keyword(s):  
Body Condition ◽  
Bitter Taste ◽  
Random Sequence ◽  
Parus Major ◽  
Taste Perception ◽  
Response Threshold ◽  
Adult Males ◽  
Taste Response ◽  
Energetic State ◽  
Prey Defenses

Abstract Many prey species contain defensive chemicals that are described as tasting bitter. Bitter taste perception is, therefore, assumed to be important when predators are learning about prey defenses. However, it is not known how individuals differ in their response to bitter taste, and how this influences their foraging decisions. We conducted taste perception assays in which wild-caught great tits (Parus major) were given water with increasing concentrations of bitter-tasting chloroquine diphosphate until they showed an aversive response to bitter taste. This response threshold was found to vary considerably among individuals, ranging from chloroquine concentrations of 0.01 mmol/L to 8 mmol/L. We next investigated whether the response threshold influenced the consumption of defended prey during avoidance learning by presenting birds with novel palatable and defended prey in a random sequence until they refused to attack defended prey. We predicted that individuals with taste response thresholds at lower concentrations would consume fewer defended prey before rejecting them, but found that the response threshold had no effect on the birds’ foraging choices. Instead, willingness to consume defended prey was influenced by the birds’ body condition. This effect was age- and sex-dependent, with adult males attacking more of the defended prey when their body condition was poor, whereas body condition did not have an effect on the foraging choices of juveniles and females. Together, our results suggest that even though taste perception might be important for recognizing prey toxicity, other factors, such as predators’ energetic state, drive the decisions to consume chemically defended prey.

Do People with Lower IQ Have Weaker Taste Perception? A Hidden Supplementary Table in ‘Is the Association Between Sweet and Bitter Perception Due to Genetic Variation?’

2020 ◽  
Vol 23 (2) ◽  
pp. 123-124
Author(s):  
Liang-Dar Hwang
Keyword(s):  
Genetic Variation ◽  
Genetic Association ◽  
Taste Perception ◽  
Taste Genetics

AbstractThis paper is about Nick’s contribution to the field of taste genetics, how I became involved and how a study on the genetic association between the perception of sweetness and bitterness ended up examining the influence of intelligence on taste perception.

scholarly journals Bitter Taste Sensitivity Is Determined by TAS2R38 Haplotype, Associated with Saturated Fat Intake and Is Lower in Overweight and Obese Compared to Normal Weight UK adults

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1271-1271
Author(s):  
Leta Pilic ◽  
Catherine Anna-Marie Graham ◽  
Nisrin Hares ◽  
Megan Brown ◽  
Jonathan Kean ◽  
...  
Keyword(s):  
Dietary Fat ◽  
Bitter Taste ◽  
Saturated Fat ◽  
Normal Weight ◽  
Taste Perception ◽  
Taste Sensitivity ◽  
Lower Sensitivity ◽  
Fat Intake ◽  
Fat Taste ◽  
Total Fat

Abstract Objectives Taste perception (sensitivity) may be determined by genetic variations in taste receptors and it affects food intake. Lower fat taste sensitivity is associated with higher dietary fat intake and body mass index (BMI). Recently, associations between bitter and fat taste sensitivity have been reported whereby bitter taste perception may be involved in textural perception of dietary fat. However, it is not clear if lower sensitivity to bitter taste would lead to an actual higher fat intake. Our objectives were to explore the associations between haplotypes in the bitter taste receptor TAS2R38, bitter taste sensitivity and fat intake and if bitter taste sensitivity is lower in individuals with higher BMI. Methods Ethical approval was obtained from the St Mary's and Oxford Brookes University Ethics Committee. Eighty-eight healthy Caucasian participants (44% male and 56% female; mean BMI 24.9 ± 4.8 kg/m2 and mean age 35 ± 14 years) completed this cross-sectional study. Height and weight were measured and genotyping performed for rs713598, rs1726866, rs10246939 genetic variants in the TAS2R38. Haplotypes were determined with Haploview software. Participants rated the intensity of a phenylthiocarbamide (PTC) impregnated strip on the general Labelled Magnitude Scale (gLMS) to determine bitter taste sensitivity and were classified as bitter tasters and non-tasters. Dietary fat intake was calculated from the EPIC-Norfolk Food Frequency Questionnaire and expressed as % total energy intake. Results TAS2R38 haplotypes were associated with bitter taster status (P < 0.005). PTC ratings of intensity were negatively correlated with % saturated fat (SFA) intake (rs = −0.256, P = 0.016). %SFA and %total fat (rs = 0.656, P < 0.005) and %total fat and energy intake (kcal) (rs = 0.225, P = 0.035) were positively correlated. Normal weight participants rated PTC strips as more intense compared to overweight and obese participants (mean rank 53 vs. 41, P = 0.033). Conclusions Bitter taste perception is determined by genetics and lower sensitivity to this taste is associated with higher intake of SFA. Lower bitter taste sensitivity in overweight/obese participants suggests that impaired bitter taste may be associated with an overall unhealthier and more energy dense dietary pattern. Funding Sources St Mary's and Oxford Brookes University.

Bitter Taste Perception and Dietary Intake Patterns in Irish Children

2013 ◽  
Vol 6 (1) ◽  
pp. 43-58 ◽  
Author(s):  
Sinead A. O'Brien ◽  
Emma L. Feeney ◽  
Amalia G.M. Scannell ◽  
Anne Markey ◽  
Eileen R. Gibney
Keyword(s):  
Dietary Intake ◽  
Bitter Taste ◽  
Taste Perception

scholarly journals Receptor Polymorphism and Genomic Structure Interact to Shape Bitter Taste Perception

PLoS Genetics ◽  
2015 ◽  
Vol 11 (9) ◽  
pp. e1005530 ◽  
Author(s):  
Natacha Roudnitzky ◽  
Maik Behrens ◽  
Anika Engel ◽  
Susann Kohl ◽  
Sophie Thalmann ◽  
...  
Keyword(s):  
Bitter Taste ◽  
Genomic Structure ◽  
Taste Perception ◽  
Receptor Polymorphism
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