scholarly journals A fully humanized transgenic mouse model of Huntington disease

2012 ◽  
Vol 22 (1) ◽  
pp. 18-34 ◽  
Author(s):  
Amber L. Southwell ◽  
Simon C. Warby ◽  
Jeffrey B. Carroll ◽  
Crystal N. Doty ◽  
Niels H. Skotte ◽  
...  
Keyword(s):  
Mouse Model ◽  
Transgenic Mouse ◽  
Huntington Disease ◽  
Transgenic Mouse Model

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

10.1038/77528 ◽  
2000 ◽  
Vol 6 (7) ◽  
pp. 797-801 ◽  
Author(s):  
Minghua Chen ◽  
Victor O. Ona ◽  
Mingwei Li ◽  
Robert J. Ferrante ◽  
Klaus B. Fink ◽  
...  
Keyword(s):  
Mouse Model ◽  
Transgenic Mouse ◽  
Huntington Disease ◽  
Caspase 3 ◽  
Transgenic Mouse Model ◽  
Caspase 1

Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease

2006 ◽  
Vol 21 (2) ◽  
pp. 392-403 ◽  
Author(s):  
Jacqueline Shehadeh ◽  
Herman B. Fernandes ◽  
Melinda M. Zeron Mullins ◽  
Rona K. Graham ◽  
Blair R. Leavitt ◽  
...  
Keyword(s):  
Nmda Receptor ◽  
Mouse Model ◽  
Transgenic Mouse ◽  
Huntington Disease ◽  
Neuronal Apoptosis ◽  
Receptor Activation ◽  
Transgenic Mouse Model ◽  
Nmda Receptor Activation

Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease

2011 ◽  
Vol 41 (2) ◽  
pp. 249-260 ◽  
Author(s):  
Jessica M. Simpson ◽  
Joana Gil-Mohapel ◽  
Mahmoud A. Pouladi ◽  
Mohamed Ghilan ◽  
Yuanyun Xie ◽  
...  
Keyword(s):  
Mouse Model ◽  
Transgenic Mouse ◽  
Huntington Disease ◽  
Transgenic Mouse Model ◽  
Hippocampal Neurogenesis ◽  
Adult Hippocampal Neurogenesis

P38 MAPK is involved in enhanced NMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease

2012 ◽  
Vol 45 (3) ◽  
pp. 999-1009 ◽  
Author(s):  
Jing Fan ◽  
Clare M. Gladding ◽  
Liang Wang ◽  
Lily Y.J. Zhang ◽  
Alexandra M. Kaufman ◽  
...  
Keyword(s):  
Nmda Receptor ◽  
Mouse Model ◽  
Transgenic Mouse ◽  
P38 Mapk ◽  
Huntington Disease ◽  
Transgenic Mouse Model
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