scholarly journals Loss of endogenous androgen receptor protein accelerates motor neuron degeneration and accentuates androgen insensitivity in a mouse model of X-linked spinal and bulbar muscular atrophy

2006 ◽  
Vol 15 (14) ◽  
pp. 2225-2238 ◽  
Author(s):  
Patrick S. Thomas ◽  
Gregory S. Fraley ◽  
Vincent Damien ◽  
Lillie B. Woodke ◽  
Francisco Zapata ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Mouse Model ◽  
Motor Neuron ◽  
Muscular Atrophy ◽  
Receptor Protein ◽  
Motor Neuron Degeneration ◽  
Neuron Degeneration ◽  
Androgen Insensitivity ◽  
Androgen Receptor Protein

scholarly journals Verapamil Ameliorates Motor Neuron Degeneration and Improves Lifespan in the SOD1G93A Mouse Model of ALS by Enhancing Autophagic Flux

2019 ◽  
Vol 10 (6) ◽  
pp. 1159 ◽  
Author(s):  
Xiaojie Zhang ◽  
Sheng Chen ◽  
Kaili Lu ◽  
Feng Wang ◽  
Jiangshan Deng ◽  
...  
Keyword(s):  
Mouse Model ◽  
Motor Neuron ◽  
Autophagic Flux ◽  
Motor Neuron Degeneration ◽  
Neuron Degeneration ◽  
Sod1g93a Mouse

scholarly journals Resolution of pathogenic R-loops rescues motor neuron degeneration in spinal muscular atrophy

Brain ◽  
2019 ◽  
Vol 143 (1) ◽  
pp. 2-5
Author(s):  
Niko Hensel ◽  
Nora Tula Detering ◽  
Lisa Marie Walter ◽  
Peter Claus
Keyword(s):  
Spinal Muscular Atrophy ◽  
Motor Neuron ◽  
Muscular Atrophy ◽  
Motor Neuron Degeneration ◽  
Neuron Degeneration

This scientific commentary refers to ‘ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy’, by Kannan et al. (doi: 10.1093/brain/awz373).

scholarly journals Neuroprotective Effects of Toll-Like Receptor 4 Antagonism in Spinal Cord Cultures and in a Mouse Model of Motor Neuron Degeneration

2012 ◽  
Vol 18 (6) ◽  
pp. 971-981 ◽  
Author(s):  
Massimiliano De Paola ◽  
Alessandro Mariani ◽  
Paolo Bigini ◽  
Marco Peviani ◽  
Giovanni Ferrara ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Mouse Model ◽  
Motor Neuron ◽  
Toll Like Receptor ◽  
Motor Neuron Degeneration ◽  
Toll Like Receptor 4 ◽  
Neuron Degeneration ◽  
Neuroprotective Effects

Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy

1998 ◽  
Vol 44 (2) ◽  
pp. 249-254 ◽  
Author(s):  
Mei Li ◽  
Shigeru Miwa ◽  
Yasushi Kobayashi ◽  
Diane E. Merry ◽  
Masahiko Yamamoto ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Muscular Atrophy ◽  
Receptor Protein ◽  
Nuclear Inclusions ◽  
Androgen Receptor Protein
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