scholarly journals Case–control study and transmission disequilibrium test provide consistent evidence for association between schizophrenia and genetic variation in the 22q11 gene ZDHHC8

2004 ◽  
Vol 13 (23) ◽  
pp. 2991-2995 ◽  
Author(s):  
Wu-Yan Chen ◽  
Yong-Yong Shi ◽  
Yong-Lan Zheng ◽  
Xin-Zhi Zhao ◽  
Guang-Ji Zhang ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Transmission Disequilibrium Test ◽  
Case Control Study ◽  
Case Control ◽  
Transmission Disequilibrium ◽  
Control Study

Genetic polymorphisms associated with pediatric‐onset type 2 diabetes: A family‐based transmission disequilibrium test and case‐control study

2019 ◽  
Vol 20 (3) ◽  
pp. 239-245
Author(s):  
América L. Miranda‐Lora ◽  
Mario Molina‐Díaz ◽  
Miguel Cruz ◽  
Rocío Sánchez‐Urbina ◽  
Nancy L. Martínez‐Rodríguez ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Genetic Polymorphisms ◽  
Transmission Disequilibrium Test ◽  
Case Control Study ◽  
Case Control ◽  
Transmission Disequilibrium ◽  
Family Based ◽  
Control Study ◽  
Pediatric Onset

BDNF Val66Met genetic variation and its plasma level in patients with morbid obesity: A case-control study

Gene ◽  
2019 ◽  
Vol 705 ◽  
pp. 51-54 ◽  
Author(s):  
Mozhdeh Zamani ◽  
Seyed Vahid Hosseini ◽  
Hamid Behrouj ◽  
Mehran Erfani ◽  
Sanaz Dastghaib ◽  
...  
Keyword(s):  
Morbid Obesity ◽  
Genetic Variation ◽  
Plasma Level ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Associations of Genetic Variation in Glyceraldehyde 3-Phosphate Dehydrogenase Gene with Noise-Induced Hearing Loss in a Chinese Population: A Case-Control Study

2020 ◽  
Vol 17 (8) ◽  
pp. 2899 ◽  
Author(s):  
Liu Wan ◽  
Boshen Wang ◽  
Juan Zhang ◽  
Baoli Zhu ◽  
Yuepu Pu
Keyword(s):  
Hearing Loss ◽  
Genetic Variation ◽  
Chinese Population ◽  
Case Control Study ◽  
Quantitative Polymerase Chain Reaction ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Noise Induced Hearing Loss ◽  
Control Study

Objective: The purpose of this paper was to clarify the association between genetic variation in the glyceraldehyde 3-phosphate dehydrogenase (GAPDH) gene and the risk of noise-induced hearing loss (NIHL). Methods: A case-control study (633 cases and 625 controls) was conducted in this study. Logistic regression was used to analyze the relationships between environmental and individual factors and NIHL. Gene expression levels were compared among each GAPDH rs6489721 genotype and between the case and control groups based on real-time fluorescence quantitative Polymerase Chain Reaction (PCR). Results: The T allele of GADPH rs6489721 was significantly associated with NIHL (odds ratio (OR) = 1.262, 95% confidence interval (CI) (1.066, 1.493), p = 0.006) and showed strong associations in the codominant and dominant models (TT vs. CC: OR = 1.586, 95% CI (1.131, 2.225), p = 0.008; TT vs. TC/CC: OR = 1.391, 95% CI (1.073, 1.804), p = 0.013). The expression level of the TT genotype was significantly higher than that of the CC genotype (p = 0.012), and the expression of the case group was also higher than that of the control group (p = 0.013). Conclusions: The homozygous risk allele (TT) of rs6489721 was associated with an enhanced GAPDH expression, resulting in the development of NIHL in a Chinese population.

scholarly journals Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

2014 ◽  
Vol 16 (3) ◽  
Author(s):  
Nichola Johnson ◽  
◽  
Frank Dudbridge ◽  
Nick Orr ◽  
Lorna Gibson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Genetic Variation ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Age At Menarche ◽  
Control Study

Abstract 2767: Genetic variation in obesity-related genes ADBR2, ADBR3, GHRL, HSD11B1, and SHC1 and risk of prostate cancer: A VA case-control study

2011 ◽  
Author(s):  
Elizabeth M. Masko ◽  
Daniel M. Moreira ◽  
Lionel L. Banez ◽  
Cathrine Hoyo ◽  
Delores J. Grant ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Genetic Variation ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

Genetic variation in D7S1875 repeat polymorphism of leptin gene is associated with increased risk for depression: a case-control study from India

2009 ◽  
Vol 26 (9) ◽  
pp. 791-795 ◽  
Author(s):  
Manav Kapoor ◽  
Suman Kapur ◽  
Shipra Mehra ◽  
Urvashi Dube ◽  
Shashwat Sharad ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Case Control Study ◽  
Case Control ◽  
Repeat Polymorphism ◽  
Increased Risk ◽  
Control Study ◽  
Risk For Depression
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