Visual and Verbal Serial List Learning in Patients with Statistically-Determined Mild Cognitive Impairment

Background/Aims: The aim of this study was to examine the associations between different cognitive domains and hand function in older people diagnosed with mild cognitive impairment (MCI) or dementia. Methods: This study is cross-sectional, including 98 community-living older people aged ≥65 years with MCI or dementia. Assessments of hand function included grip strength, the Finger Tapping Test, and the Grooved Pegboard. Cognitive assessments were the Mini-Mental State Examination, the Clock Drawing Test, and Trail Making Tests A and B, as well as a 10-word List Learning Test. Statistical analyses were based on descriptive statistics and univariable and multivariable analyses. Results: Sixty participants were diagnosed with MCI and 38 were diagnosed with dementia. The mean age was 78.8 years (SD 7.4). Analyses of hand function, cognitive tests, and demographic factors showed an association between cognitive tests, in particular executive function (EF), and hand function. Conclusions: The findings indicated an association between physical and cognitive function. Among the cognitive domains, declines in EF were most related to a reduced physical function.

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Comparison between the Story Recall Test and the Word-List Learning Test in Korean patients with mild cognitive impairment and early stage of Alzheimer's disease

Journal of Clinical and Experimental Neuropsychology ◽

10.1080/13803395.2011.645020 ◽

2012 ◽

Vol 34 (4) ◽

pp. 396-404 ◽

Cited By ~ 21

Author(s):

Min Jae Baek ◽

Hyun Jung Kim ◽

SangYun Kim

Keyword(s):

Alzheimer’S Disease ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Recall Test ◽

Early Stage ◽

Word List ◽

Story Recall ◽

Korean Patients ◽

List Learning ◽

Learning Test

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Diagnostic utility of the NAB List Learning test in Alzheimer’s disease and amnestic mild cognitive impairment

Journal of the International Neuropsychological Society ◽

10.1017/s1355617708090176 ◽

2009 ◽

Vol 15 (1) ◽

pp. 121-129 ◽

Cited By ~ 28

Author(s):

BRANDON E. GAVETT ◽

SABRINA J. POON ◽

AL OZONOFF ◽

ANGELA L. JEFFERSON ◽

ANIL K. NAIR ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Learning Performance ◽

Diagnostic Utility ◽

Operating Characteristics ◽

Promising Tool ◽

List Learning ◽

Learning Test

AbstractMeasures of episodic memory are often used to identify Alzheimer’s disease (AD) and mild cognitive impairment (MCI). The Neuropsychological Assessment Battery (NAB) List Learning test is a promising tool for the memory assessment of older adults due to its simplicity of administration, good psychometric properties, equivalent forms, and extensive normative data. This study examined the diagnostic utility of the NAB List Learning test for differentiating cognitively healthy, MCI, and AD groups. One hundred fifty-three participants (age: range, 57–94 years;M= 74 years;SD,8 years; sex: 61% women) were diagnosed by a multidisciplinary consensus team as cognitively normal, amnestic MCI (aMCI; single and multiple domain), or AD, independent of NAB List Learning performance. In univariate analyses, receiver operating characteristics curve analyses were conducted for four demographically-corrected NAB List Learning variables. Additionally, multivariate ordinal logistic regression and fivefold cross-validation was used to create and validate a predictive model based on demographic variables and NAB List Learning test raw scores. At optimal cutoff scores, univariate sensitivity values ranged from .58 to .92 and univariate specificity values ranged from .52 to .97. Multivariate ordinal regression produced a model that classified individuals with 80% accuracy and good predictive power. (JINS, 2009,15, 121–129.)

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