scholarly journals Genome-Wide Analysis of Evolutionary Markers of Human Influenza A(H1N1)pdm09 and A(H3N2) Viruses May Guide Selection of Vaccine Strain Candidates

2015 ◽  
Vol 7 (12) ◽  
pp. 3472-3483 ◽  
Author(s):  
Sergei S. Belanov ◽  
Dmitrii Bychkov ◽  
Christian Benner ◽  
Samuli Ripatti ◽  
Teija Ojala ◽  
...  
Keyword(s):  
Vaccine Strain ◽  
Influenza A ◽  
Human Influenza ◽  
Genome Wide Analysis ◽  
Genome Wide ◽  
Influenza A H1n1 ◽  
Selection Of

scholarly journals Virological analysis of fatal influenza cases in the United Kingdom during the early wave of influenza in winter 2010/11

2011 ◽  
Vol 16 (1) ◽  
Author(s):  
J Ellis ◽  
M Galiano ◽  
R Pebody ◽  
A Lackenby ◽  
CI Thompson ◽  
...  
Keyword(s):  
United Kingdom ◽  
Vaccine Strain ◽  
Influenza A ◽  
Influenza Season ◽  
Severe Illness ◽  
Influenza B ◽  
The United Kingdom ◽  
Influenza A H1n1 ◽  
Influenza Activity ◽  
Children And Young Adults

The 2010/11 winter influenza season is underway in the United Kingdom, with co-circulation of influenza A(H1N1)2009 (antigenically similar to the current 2010/11 vaccine strain), influenza B (mainly B/Victoria/2/87 lineage, similar to the 2010/11 vaccine strain) and a few sporadic influenza A(H3N2) viruses. Clinical influenza activity has been increasing. Severe illness, resulting in hospitalisation and deaths, has occurred in children and young adults and has predominantly been associated with influenza A(H1N1)2009, but also influenza B viruses.

Antigenic and genomic characterization of human influenza A and B viruses circulating in Argentina after the introduction of influenza A(H1N1)pdm09

2014 ◽  
Vol 63 (12) ◽  
pp. 1626-1637 ◽  
Author(s):  
Mara L. Russo ◽  
Andrea V. Pontoriero ◽  
Estefania Benedetti ◽  
Andrea Czech ◽  
Martin Avaro ◽  
...  
Keyword(s):  
Southern Hemisphere ◽  
Influenza A ◽  
Vaccine Virus ◽  
Influenza Viruses ◽  
World Health ◽  
Influenza Surveillance ◽  
Human Influenza ◽  
Surveillance Network ◽  
Influenza A H1n1 ◽  
Health Organization

This study was conducted as part of the Argentinean Influenza and other Respiratory Viruses Surveillance Network, in the context of the Global Influenza Surveillance carried out by the World Health Organization (WHO). The objective was to study the activity and the antigenic and genomic characteristics of circulating viruses for three consecutive seasons (2010, 2011 and 2012) in order to investigate the emergence of influenza viral variants. During the study period, influenza virus circulation was detected from January to December. Influenza A and B, and all current subtypes of human influenza viruses, were present each year. Throughout the 2010 post-pandemic season, influenza A(H1N1)pdm09, unexpectedly, almost disappeared. The haemagglutinin (HA) of the A(H1N1)pdm09 viruses studied were segregated in a different genetic group to those identified during the 2009 pandemic, although they were still antigenically closely related to the vaccine strain A/California/07/2009. Influenza A(H3N2) viruses were the predominant strains circulating during the 2011 season, accounting for nearly 76 % of influenza viruses identified. That year, all HA sequences of the A(H3N2) viruses tested fell into the A/Victoria/208/2009 genetic clade, but remained antigenically related to A/Perth/16/2009 (reference vaccine recommended for this three-year period). A(H3N2) viruses isolated in 2012 were antigenically closely related to A/Victoria/361/2011, recommended by the WHO as the H3 component for the 2013 Southern Hemisphere formulation. B viruses belonging to the B/Victoria lineage circulated in 2010. A mixed circulation of viral variants of both B/Victoria and B/Yamagata lineages was detected in 2012, with the former being predominant. A(H1N1)pdm09 viruses remained antigenically closely related to the vaccine virus A/California/7/2009; A(H3N2) viruses continually evolved into new antigenic clusters and both B lineages, B/Victoria/2/87-like and B/Yamagata/16/88-like viruses, were observed during the study period. The virological surveillance showed that the majority of the circulating strains during the study period were antigenically related to the corresponding Southern Hemisphere vaccine strains except for the 2012 A(H3N2) viruses.

scholarly journals Antigenic Patterns and Evolution of the Human Influenza A (H1N1) Virus

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Mi Liu ◽  
Xiang Zhao ◽  
Sha Hua ◽  
Xiangjun Du ◽  
Yousong Peng ◽  
...  
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
Human Influenza ◽  
Influenza A H1n1

scholarly journals Pathogenesis and Chronologic Localization of the Human Influenza A (H1N1) Virus in Cotton Rats

2011 ◽  
Vol 2 (1) ◽  
pp. 15-22 ◽  
Author(s):  
Donghyok Kwon ◽  
Kyeongcheol Shin ◽  
Jin-Young Shin ◽  
Joo-Yeon Lee ◽  
Yooncheol Ha ◽  
...  
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
Human Influenza ◽  
Influenza A H1n1 ◽  
Cotton Rats

scholarly journals Genetic Makeup of Amantadine-Resistant and Oseltamivir-Resistant Human Influenza A/H1N1 Viruses

2010 ◽  
Vol 48 (4) ◽  
pp. 1085-1092 ◽  
Author(s):  
H. Zaraket ◽  
R. Saito ◽  
Y. Suzuki ◽  
T. Baranovich ◽  
C. Dapat ◽  
...  
Keyword(s):  
Influenza A ◽  
Human Influenza ◽  
Influenza A H1n1 ◽  
Genetic Makeup

Recent human influenza A (H1N1) viruses are closely related genetically to strains isolated in 1950

Nature ◽  
1978 ◽  
Vol 274 (5669) ◽  
pp. 334-339 ◽  
Author(s):  
Katsuhisa Nakajima ◽  
Ulrich Desselberger ◽  
Peter Palese
Keyword(s):  
Influenza A ◽  
Human Influenza ◽  
Influenza A H1n1

scholarly journals Effectiveness of Common Household Cleaning Agents in Reducing the Viability of Human Influenza A/H1N1

PLoS ONE ◽  
2010 ◽  
Vol 5 (2) ◽  
pp. e8987 ◽  
Author(s):  
Jane S. Greatorex ◽  
Rosanna F. Page ◽  
Martin D. Curran ◽  
Paul Digard ◽  
Joanne E. Enstone ◽  
...  
Keyword(s):  
Influenza A ◽  
Human Influenza ◽  
Cleaning Agents ◽  
Influenza A H1n1 ◽  
Household Cleaning
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