scholarly journals The Full Globin Repertoire of Turtles Provides Insights into Vertebrate Globin Evolution and Functions

2015 ◽  
Vol 7 (7) ◽  
pp. 1896-1913 ◽  
Author(s):  
Kim Schwarze ◽  
Abhilasha Singh ◽  
Thorsten Burmester
Keyword(s):  
Globin Evolution

Globin evolution in some species of the genus bufo

1984 ◽  
Vol 78 (1) ◽  
pp. 21-25
Author(s):  
P. Cardellini ◽  
G. Casas Andreu ◽  
D Goenarso ◽  
L. Guidolin ◽  
R. Martino ◽  
...  
Keyword(s):  
Globin Evolution

scholarly journals Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals

BMC Biology ◽  
2008 ◽  
Vol 6 (1) ◽  
Author(s):  
Vidushi S Patel ◽  
Steven JB Cooper ◽  
Janine E Deakin ◽  
Bob Fulton ◽  
Tina Graves ◽  
...  
Keyword(s):  
Globin Genes ◽  
Beta Globin ◽  
Globin Evolution

scholarly journals Globins in the marine annelid Platynereis dumerilii shed new light on hemoglobin evolution in bilaterians

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Solène Song ◽  
Viktor Starunov ◽  
Xavier Bailly ◽  
Christine Ruta ◽  
Pierre Kerner ◽  
...  
Keyword(s):  
Vascular System ◽  
Large Family ◽  
Early Gene ◽  
Last Common Ancestor ◽  
Globin Genes ◽  
Single Clade ◽  
Platynereis Dumerilii ◽  
Globin Evolution ◽  
Using Data ◽  
Animal Size

Abstract Background How vascular systems and their respiratory pigments evolved is still debated. While many animals present a vascular system, hemoglobin exists as a blood pigment only in a few groups (vertebrates, annelids, a few arthropod and mollusk species). Hemoglobins are formed of globin sub-units, belonging to multigene families, in various multimeric assemblages. It was so far unclear whether hemoglobin families from different bilaterian groups had a common origin. Results To unravel globin evolution in bilaterians, we studied the marine annelid Platynereis dumerilii, a species with a slow evolving genome. Platynereis exhibits a closed vascular system filled with extracellular hemoglobin. Platynereis genome and transcriptomes reveal a family of 19 globins, nine of which are predicted to be extracellular. Extracellular globins are produced by specialized cells lining the vessels of the segmental appendages of the worm, serving as gills, and thus likely participate in the assembly of a previously characterized annelid-specific giant hemoglobin. Extracellular globin mRNAs are absent in smaller juveniles, accumulate considerably in growing and more active worms and peak in swarming adults, as the need for O2 culminates. Next, we conducted a metazoan-wide phylogenetic analysis of globins using data from complete genomes. We establish that five globin genes (stem globins) were present in the last common ancestor of bilaterians. Based on these results, we propose a new nomenclature of globins, with five clades. All five ancestral stem-globin clades are retained in some spiralians, while some clades disappeared early in deuterostome and ecdysozoan evolution. All known bilaterian blood globin families are grouped in a single clade (clade I) together with intracellular globins of bilaterians devoid of red blood. Conclusions We uncover a complex “pre-blood” evolution of globins, with an early gene radiation in ancestral bilaterians. Circulating hemoglobins in various bilaterian groups evolved convergently, presumably in correlation with animal size and activity. However, all hemoglobins derive from a clade I globin, or cytoglobin, probably involved in intracellular O2 transit and regulation. The annelid Platynereis is remarkable in having a large family of extracellular blood globins, while retaining all clades of ancestral bilaterian globins.

scholarly journals Globins in the marine Annelid Platynereis dumerilii shed new light on hemoglobin evolution in Bilaterians

2019 ◽  
Author(s):  
Solène Song ◽  
Viktor Starunov ◽  
Xavier Bailly ◽  
Christine Ruta ◽  
Pierre Kerner ◽  
...  
Keyword(s):  
Vascular System ◽  
Large Family ◽  
Early Gene ◽  
Last Common Ancestor ◽  
Globin Genes ◽  
Single Clade ◽  
Platynereis Dumerilii ◽  
Globin Evolution ◽  
Using Data ◽  
Animal Size

AbstractBackgroundHow vascular systems and their respiratory pigments evolved is still debated. While many animals present a vascular system, hemoglobin exists as a blood pigment only in a few groups (Vertebrates, Annelids, a few Arthropod and Mollusk species). Hemoglobins are formed of globin sub-units, belonging to multigene families, in various multimeric assemblages. It was so far unclear whether hemoglobin families from different Bilaterian groups had a common origin.ResultsTo unravel globin evolution in Bilaterians, we studied the marine Annelid Platynereis dumerilii, a species with a slow evolving genome. Platynereis exhibits a closed vascular system filled with extracellular hemoglobin. Platynereis genome and transcriptomes reveal a family of 19 globins, nine of which are predicted to be extracellular. Extracellular globins are produced by specialized cells lining the vessels of the segmental appendages of the worm, serving as gills, and thus likely participate in the assembly of the giant hexagonal bilayer hemoglobin of the worm. Extracellular globin mRNAs are absent in smaller juvenile, accumulate considerably in growing and more active worms and peak in swarming adults, as the need for O2 culminates. Next, we conducted a Metazoan-wide phylogenetic analysis of globins using data from complete genomes. We establish that five globin genes (stem globins) were present in the last common ancestor of Bilaterians. Based on these results, we propose a new nomenclature of globins, with five clades. All five ancestral stem-globin clades are retained in some Spiralians, while some clades disappeared early in Deuterostome and Ecdysozoan evolution. All known Bilaterian blood globin families are grouped in a single clade (clade I) together with intracellular globins of Bilaterians devoid of red blood.ConclusionsWe uncover a complex “pre-blood” evolution of globins, with an early gene radiation in ancestral Bilaterians. Circulating hemoglobins in various bilaterian groups evolved convergently, presumably in correlation with animal size and activity. However, all hemoglobins derive from a clade I globin, or cytoglobin, probably involved in intracellular O2 transit and regulation (clade I). The Annelid Platynereis is remarkable in having a large family of extracellular blood globins, while retaining all clades of ancestral Bilaterian globins.

scholarly journals The globin gene family of the cephalochordate amphioxus: implications for chordate globin evolution

2010 ◽  
Vol 10 (1) ◽  
pp. 370 ◽  
Author(s):  
Bettina Ebner ◽  
Georgia Panopoulou ◽  
Serge N Vinogradov ◽  
Laurent Kiger ◽  
Michael C Marden ◽  
...  
Keyword(s):  
Gene Family ◽  
Globin Gene ◽  
Globin Evolution
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