scholarly journals Genome Diversity and Divergence in Drosophila mauritiana : Multiple Signatures of Faster X Evolution

2014 ◽  
Vol 6 (9) ◽  
pp. 2444-2458 ◽  
Author(s):  
Daniel Garrigan ◽  
Sarah B. Kingan ◽  
Anthony J. Geneva ◽  
Jeffrey P. Vedanayagam ◽  
Daven C. Presgraves
Keyword(s):  
Genome Diversity ◽  
Drosophila Mauritiana

scholarly journals Genome Diversity and Divergence in Drosophila mauritiana: Multiple Signatures of Faster X Evolution

2015 ◽  
Vol 7 (5) ◽  
pp. 1331-1331 ◽  
Author(s):  
D. Garrigan ◽  
S. B. Kingan ◽  
A. J. Geneva ◽  
J. P. Vedanayagam ◽  
D. C. Presgraves
Keyword(s):  
Genome Diversity ◽  
Drosophila Mauritiana

scholarly journals Hidden Effects of X Chromosome Introgressions on Spermatogenesis in Drosophila simulans × D. mauritiana Hybrids Unveiled by Interactions Among Minor Genetic Factors

Genetics ◽  
1998 ◽  
Vol 150 (2) ◽  
pp. 745-754 ◽  
Author(s):  
Xulio R Maside ◽  
José P Barral ◽  
Horacio F Naveira
Keyword(s):  
Male Sterility ◽  
X Chromosome ◽  
Seminal Vesicles ◽  
Genetic Dissection ◽  
Research Strategies ◽  
Hybrid Male ◽  
Hybrid Male Sterility ◽  
Epistatic Interactions ◽  
Drosophila Mauritiana ◽  
Chromosome Segments

Abstract One of the most frequent outcomes of interspecific hybridizations in Drosophila is hybrid male sterility. Genetic dissection of this reproductive barrier has revealed that the number of responsible factors is very high and that these factors are frequently engaged in complex epistatic interactions. Traditionally, research strategies have been based on contrasting introgressions of chromosome segments that produce male sterility with those that allow fertility. Few studies have investigated the phenotypes associated with the boundary between fertility and sterility. In this study, we cointrogressed three different X chromosome segments from Drosophila mauritiana into D. simulans. Hybrid males with these three segments are usually fertile, by conventional fertility assays. However, their spermatogenesis shows a significant slowdown, most manifest at lower temperatures. Each of the three introgressed segments retards the arrival of sperm to the seminal vesicles. Other small disturbances in spermatogenesis are evident, which altogether lead to an overall reduction in the amount of motile sperm in their seminal vesicles. These results suggest that a delay in the timing of spermatogenesis, which might be brought about by the cumulative action of many different factors of minor segment, may be the primary cause of hybrid male sterility.

scholarly journals Germline Transformation of Drosophila virilis With the Transposable Element mariner

Genetics ◽  
1996 ◽  
Vol 143 (1) ◽  
pp. 365-374 ◽  
Author(s):  
Allan R Lohe ◽  
Daniel L Hartl
Keyword(s):  
Transposable Element ◽  
Common Ancestor ◽  
Pcr Amplification ◽  
Drosophila Virilis ◽  
Cell Region ◽  
Diverse Species ◽  
Drosophila Mauritiana ◽  
Characteristic 2 ◽  
In Situ Hybridizations

Abstract An important goal in molecular genetics has been to identify a transposable element that might serve as an efficient transformation vector in diverse species of insects. The transposable element mariner occurs naturally in a wide variety of insects. Although virtually all mariner elements are nonfunctional, the Mosl element isolated from Drosophila mauritiana is functional. Mosl was injected into the pole-cell region of embryos of D. virilis, which last shared a common ancestor with D. mauritiana 40 million years ago. Mosl PCR fragments were detected in several pools of DNA from progeny of injected animals, and backcross lines were established. Because Go lines were pooled, possibly only one transformation event was actually obtained, yielding a minimum frequency of 4%. Mosl segregated in a Mendelian fashion, demonstrating chromosomal integration. The copy number increased by spontaneous mobilization. In situ hybridization confirmed multiple polymorphic locations of Mosl. Integration results in a characteristic 2-bp TA duplication. One Mosl element integrated into a tandem array of 370-bp repeats. Some copies may have integrated into heterochromatin, as evidenced by their ability to support PCR amplification despite absence of a signal in Southern and in situ hybridizations.

scholarly journals Diversity of SARS-CoV-2 isolates driven by pressure and health index

2021 ◽  
Vol 149 ◽  
Author(s):  
R. K. Sanayaima Singh ◽  
Md. Zubbair Malik ◽  
R. K. Brojen Singh
Keyword(s):  
Fractal Dimension ◽  
Severe Acute Respiratory Syndrome ◽  
Mutation Rate ◽  
Hurst Exponent ◽  
Viral Genome ◽  
Critical Pressure ◽  
Genome Organisation ◽  
Health Index ◽  
Genome Diversity ◽  
Fast Spreading

Abstract One of the main concerns about the fast spreading coronavirus disease 2019 (Covid-19) pandemic is how to intervene. We analysed severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) isolates data using the multifractal approach and found a rich in viral genome diversity, which could be one of the root causes of the fast Covid-19 pandemic and is strongly affected by pressure and health index of the hosts inhabited regions. The calculated mutation rate (mr) is observed to be maximum at a particular pressure, beyond which mr maintains diversity. Hurst exponent and fractal dimension are found to be optimal at a critical pressure (Pm), whereas, for P > Pm and P < Pm, we found rich genome diversity relating to complicated genome organisation and virulence of the virus. The values of these complexity measurement parameters are found to be increased linearly with health index values.

scholarly journals Complete nucleotide sequence of the A+T-rich region of Drosophila mauritiana mitochondrial DNA

2006 ◽  
Vol 81 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Kanako Sugihara ◽  
Ryoko Yui ◽  
Yoko Ibaragi ◽  
Etsuko T. Matsuura
Keyword(s):  
Mitochondrial Dna ◽  
Nucleotide Sequence ◽  
Complete Nucleotide Sequence ◽  
Rich Region ◽  
Drosophila Mauritiana

Sa536 GENOME DIVERSITY OF INTESTINAL ESCHERICHIA COLI STRAINS FROM PATIENTS WITH CROHN'S DISEASE AND HEALTHY INDIVIDUALS

2021 ◽  
Vol 160 (6) ◽  
pp. S-539
Author(s):  
Maria Siniagina ◽  
Maria Markelova ◽  
Alexander Laikov ◽  
Dilyara Khusnutdinova ◽  
Eugenia A. Boulygina ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Healthy Individuals ◽  
Genome Diversity

scholarly journals Genome diversity in the Neolithic Globular Amphorae culture and the spread of Indo-European languages

2017 ◽  
Vol 284 (1867) ◽  
pp. 20171540 ◽  
Author(s):  
Francesca Tassi ◽  
Stefania Vai ◽  
Silvia Ghirotto ◽  
Martina Lari ◽  
Alessandra Modi ◽  
...  
Keyword(s):  
Approximate Bayesian Computation ◽  
Cultural Influences ◽  
Archaeological Record ◽  
Genome Diversity ◽  
Early Neolithic ◽  
Late Neolithic ◽  
Demographic Models ◽  
European Languages ◽  
Complete Sequences ◽  
Approximate Bayesian

It is unclear whether Indo-European languages in Europe spread from the Pontic steppes in the late Neolithic, or from Anatolia in the Early Neolithic. Under the former hypothesis, people of the Globular Amphorae culture (GAC) would be descended from Eastern ancestors, likely representing the Yamnaya culture. However, nuclear (six individuals typed for 597 573 SNPs) and mitochondrial (11 complete sequences) DNA from the GAC appear closer to those of earlier Neolithic groups than to the DNA of all other populations related to the Pontic steppe migration. Explicit comparisons of alternative demographic models via approximate Bayesian computation confirmed this pattern. These results are not in contrast to Late Neolithic gene flow from the Pontic steppes into Central Europe. However, they add nuance to this model, showing that the eastern affinities of the GAC in the archaeological record reflect cultural influences from other groups from the East, rather than the movement of people.

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