scholarly journals Highlight--Small Genomes for the Swift: Of Flight and Intron Size

2012 ◽  
Vol 4 (10) ◽  
pp. 1044-1045
Author(s):  
D. Venton
Keyword(s):  
Intron Size

scholarly journals Selective Constraints on Intron Evolution in Drosophila

Genetics ◽  
2003 ◽  
Vol 165 (4) ◽  
pp. 1843-1851 ◽  
Author(s):  
John Parsch
Keyword(s):  
Drosophila Melanogaster ◽  
Natural Selection ◽  
Common Ancestor ◽  
Length Distribution ◽  
Short Length ◽  
Intron Length ◽  
Intron Evolution ◽  
Intron Size ◽  
Duplicated Genes ◽  
Selective Constraints

AbstractIntron sizes show an asymmetrical distribution in a number of organisms, with a large number of “short” introns clustered around a minimal intron length and a much broader distribution of longer introns. In Drosophila melanogaster, the short intron class is centered around 61 bp. The narrow length distribution suggests that natural selection may play a role in maintaining intron size. A comparison of 15 orthologous introns among species of the D. melanogaster subgroup indicates that, in general, short introns are not under greater DNA sequence or length constraints than long introns. There is a bias toward deletions in all introns (deletion/insertion ratio is 1.66), and the vast majority of indels are of short length (<10 bp). Indels occurring on the internal branches of the phylogenetic tree are significantly longer than those occurring on the terminal branches. These results are consistent with a compensatory model of intron length evolution in which slightly deleterious short deletions are frequently fixed within species by genetic drift, and relatively rare larger insertions that restore intron length are fixed by positive selection. A comparison of paralogous introns shared among duplicated genes suggests that length constraints differ between introns within the same gene. The janusA, janusB, and ocnus genes share two short introns derived from a common ancestor. The first of these introns shows significantly fewer indels than the second intron, although the two introns show a comparable number of substitutions. This indicates that intron-specific selective constraints have been maintained following gene duplication, which preceded the divergence of the D. melanogaster species subgroup.

scholarly journals Effect of intron size on splicing efficiency in retroviral transcripts

1982 ◽  
Vol 10 (19) ◽  
pp. 6177-6190 ◽  
Author(s):  
Bryan R. Cullen ◽  
John J. Kopchick ◽  
Dennis W. Stacey
Keyword(s):  
Intron Size ◽  
Splicing Efficiency ◽  
Retroviral Transcripts

Systematic analysis of intron size and abundance parameters in diverse lineages

2013 ◽  
Vol 56 (10) ◽  
pp. 968-974 ◽  
Author(s):  
Wu JiaYan ◽  
Xiao JingFa ◽  
Wang LingPing ◽  
Zhong Jun ◽  
Yin HongYan ◽  
...  
Keyword(s):  
Intron Size ◽  
Systematic Analysis

scholarly journals Transposon-Derived and Satellite-Derived Repetitive Sequences Play Distinct Functional Roles in Mammalian Intron Size Expansion

2012 ◽  
Vol 8 ◽  
pp. EBO.S9758 ◽  
Author(s):  
Dapeng Wang ◽  
Yao Su ◽  
Xumin Wang ◽  
Hongxing Lei ◽  
Jun Yu
Keyword(s):  
Repetitive Sequences ◽  
Intron Size ◽  
Functional Roles

scholarly journals Comparative Analysis of Teleost Genome Sequences Reveals an Ancient Intron Size Expansion in the Zebrafish Lineage

2011 ◽  
Vol 3 ◽  
pp. 1187-1196 ◽  
Author(s):  
Stephen P. Moss ◽  
Domino A. Joyce ◽  
Stuart Humphries ◽  
Katherine J. Tindall ◽  
David H. Lunt
Keyword(s):  
Comparative Analysis ◽  
Intron Size ◽  
Genome Sequences ◽  
Teleost Genome

scholarly journals Intron Size Correlates Positively With Recombination Rate in Caenorhabditis elegans

Genetics ◽  
2004 ◽  
Vol 166 (3) ◽  
pp. 1585-1590 ◽  
Author(s):  
Anuphap Prachumwat ◽  
Laura DeVincentis ◽  
Michael F. Palopoli
Keyword(s):  
Caenorhabditis Elegans ◽  
Recombination Rate ◽  
Intron Size

scholarly journals Intron Size and Exon Evolution in Drosophila

Genetics ◽  
2005 ◽  
Vol 170 (1) ◽  
pp. 481-485 ◽  
Author(s):  
Gabriel Marais ◽  
Pierre Nouvellet ◽  
Peter D. Keightley ◽  
Brian Charlesworth
Keyword(s):  
Intron Size ◽  
Exon Evolution
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