scholarly journals Can Intra-Y Gene Conversion Oppose the Degeneration of the Human Y Chromosome?: A Simulation Study

2010 ◽  
Vol 2 (0) ◽  
pp. 347-357 ◽  
Author(s):  
G. A. B. Marais ◽  
P. R. A. Campos ◽  
I. Gordo
Keyword(s):  
Gene Conversion ◽  
Y Chromosome ◽  
Simulation Study ◽  
Human Y Chromosome

The degenerate Y chromosome – can conversion save it?

2004 ◽  
Vol 16 (5) ◽  
pp. 527 ◽  
Author(s):  
Jennifer A. Marshall Graves
Keyword(s):  
Gene Conversion ◽  
Y Chromosome ◽  
Genetic Drift ◽  
Sex Chromosome ◽  
Chromosome Differentiation ◽  
Y Chromosomes ◽  
Speed Up ◽  
Selection For ◽  
Human Y Chromosome

The human Y chromosome is running out of time. In the last 300 million years, it has lost 1393 of its original 1438 genes, and at this rate it will lose the last 45 in a mere 10 million years. But there has been a proposal that perhaps rescue is at hand in the form of recently discovered gene conversion within palindromes. However, I argue here that although conversion will increase the frequency of variation of the Y (particularly amplification) between Y chromosomes in a population, it will not lead to a drive towards a more functional Y. The forces of evolution have made the Y a genetically isolated, non-recombining entity, vulnerable to genetic drift and selection for favourable new variants sharing the Y with damaging mutations. Perhaps it will even speed up the decline of the Y chromosome and the onset of a new round of sex-chromosome differentiation. The struggle to preserve males may perhaps lead to hominid speciation.

scholarly journals Copy number variation arising from gene conversion on the human Y chromosome

2017 ◽  
Vol 137 (1) ◽  
pp. 73-83 ◽  
Author(s):  
Wentao Shi ◽  
Andrea Massaia ◽  
Sandra Louzada ◽  
Ruby Banerjee ◽  
Pille Hallast ◽  
...  
Keyword(s):  
Copy Number Variation ◽  
Gene Conversion ◽  
Y Chromosome ◽  
Copy Number ◽  
Number Variation ◽  
Human Y Chromosome

scholarly journals Association of the Human Y Chromosome with Cholesterol Levels in the General Population

2004 ◽  
Vol 24 (2) ◽  
pp. 308-312 ◽  
Author(s):  
Fadi J. Charchar ◽  
Maciej Tomaszewski ◽  
Beata Lacka ◽  
Jaroslaw Zakrzewski ◽  
Ewa Zukowska-Szczechowska ◽  
...  
Keyword(s):  
General Population ◽  
Y Chromosome ◽  
Cholesterol Levels ◽  
Human Y Chromosome

scholarly journals A Back Migration from Asia to Sub-Saharan Africa Is Supported by High-Resolution Analysis of Human Y-Chromosome Haplotypes

2002 ◽  
Vol 70 (5) ◽  
pp. 1197-1214 ◽  
Author(s):  
Fulvio Cruciani ◽  
Piero Santolamazza ◽  
Peidong Shen ◽  
Vincent Macaulay ◽  
Pedro Moral ◽  
...  
Keyword(s):  
High Resolution ◽  
Y Chromosome ◽  
Sub Saharan Africa ◽  
High Resolution Analysis ◽  
Resolution Analysis ◽  
Sub Saharan ◽  
Human Y Chromosome

DA/DAPI-Fluorescent heteromorphism of human Y chromosome

1988 ◽  
Vol 79 (1) ◽  
pp. 36-38 ◽  
Author(s):  
M. S. Lin ◽  
A. Zhang ◽  
M. G. Wilson ◽  
A. Fujimoto
Keyword(s):  
Y Chromosome ◽  
Human Y Chromosome

Human Y chromosome isn't wasting away

Lab Animal ◽  
2012 ◽  
Vol 41 (4) ◽  
pp. 89-89
Author(s):  
Monica Harrington
Keyword(s):  
Y Chromosome ◽  
Human Y Chromosome

Additional deletion in sex-determining region of human Y chromosome resolves paradox of X,t(Y;22) female

Nature ◽  
1990 ◽  
Vol 346 (6281) ◽  
pp. 279-281 ◽  
Author(s):  
David C. Page ◽  
Elizabeth M. C. Fisher ◽  
Barbara McGillivray ◽  
Laura G. Brown
Keyword(s):  
Y Chromosome ◽  
Human Y Chromosome
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