scholarly journals The Love Story Between Orai Calcium Entry Channels and Adenylyl Cyclases Gets Even More Complicated

Function ◽  
2021 ◽  
Author(s):  
Aldebaran M Hofer
2019 ◽  
Vol 47 (6) ◽  
pp. 1733-1747 ◽  
Author(s):  
Christina Klausen ◽  
Fabian Kaiser ◽  
Birthe Stüven ◽  
Jan N. Hansen ◽  
Dagmar Wachten

The second messenger 3′,5′-cyclic nucleoside adenosine monophosphate (cAMP) plays a key role in signal transduction across prokaryotes and eukaryotes. Cyclic AMP signaling is compartmentalized into microdomains to fulfil specific functions. To define the function of cAMP within these microdomains, signaling needs to be analyzed with spatio-temporal precision. To this end, optogenetic approaches and genetically encoded fluorescent biosensors are particularly well suited. Synthesis and hydrolysis of cAMP can be directly manipulated by photoactivated adenylyl cyclases (PACs) and light-regulated phosphodiesterases (PDEs), respectively. In addition, many biosensors have been designed to spatially and temporarily resolve cAMP dynamics in the cell. This review provides an overview about optogenetic tools and biosensors to shed light on the subcellular organization of cAMP signaling.


1999 ◽  
Author(s):  
Michelle Le Brun
Keyword(s):  

Author(s):  
Dandy Ashghor Dawudi ◽  
Kamidjan Kamidjan ◽  
Agus Sulton

This research takes the object of Sebening Syahadat by Diva SR, this work is a novel that tells the story of the journey ofa teenager named Sam who is in the process ofsearching for identity. The journey is filled with interesting twits and turns embelissed with a love story that is very suitable if consumed by the younger generation who are learning to find identit. This study aims to reveal the value motives that led Sam’s character in finding his identity, which expected to be a material for reflection for readers, especially young people who are in the process of discovering his identity, the scope of the problem in this study is to reveal the value motives that affect the character’s psyche. Sam is told to have a rascal character.The research method used in this study took a descriptive qualitative approach, data colletion used was a literature study technique with stages of reading, note taking, coding for futher analysis. The analysis technique used is qualitative descriptive analysis technique.The result of the research in this research process indicate that the mental process of Sam’s character influenced by several factors, including: a. Motives in cultural factors (Situasional Factors), b. The motive for love begins with admiration for the attitude of someone who is full of noble values of character, c. The motive of curiosity and fulfillment of his needs for true value.


2011 ◽  
Vol 4 (4) ◽  
pp. 361-384
Author(s):  
Ulises Moreno Tabarez

Representations of Mexican revolutionary hero, Emiliano Zapata, migrate across the Mexico/US borders. His specters inform and reflect sexual identities migrating across these borderlands. Theoretically guided by Madison's model of performative writing and Muñoz's disidentification, this experimental project highlights and challenges the heteronormativity that pervades these migratory representations and the discursive practices that bring them to life. Through a performative writing exercise, I travel through theory and time to (re)present the figure of Zapata in an intimate love story whose backdrop is violence and war.


Diabetes ◽  
1986 ◽  
Vol 35 (11) ◽  
pp. 1206-1214 ◽  
Author(s):  
T. Baba ◽  
T. Ishizaki ◽  
Y. Ido ◽  
K. Aoyagi ◽  
S. Murabayashi ◽  
...  

1997 ◽  
Author(s):  
Michele Dunn Baker
Keyword(s):  

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