scholarly journals Simulated climate warming and mitochondrial haplogroup modulate testicular small non-coding RNA expression in the neotropical pseudoscorpion,Cordylochernes scorpioides

2018 ◽  
Vol 4 (4) ◽  
Author(s):  
Eleanor J Su-Keene ◽  
Melvin M Bonilla ◽  
Michael V Padua ◽  
David W Zeh ◽  
Jeanne A Zeh
Keyword(s):  
Climate Warming ◽  
Rna Expression ◽  
Mitochondrial Haplogroup ◽  
Non Coding Rna ◽  
Simulated Climate ◽  
Cordylochernes Scorpioides

Long non-coding RNA expression profiles in human parathyroid tumors

2017 ◽  
Author(s):  
Annamaria Morotti ◽  
Irene Forno ◽  
Valentina Andre ◽  
Andrea Terrasi ◽  
Chiara Verdelli ◽  
...  
Keyword(s):  
Expression Profiles ◽  
Rna Expression ◽  
Parathyroid Tumors ◽  
Non Coding Rna ◽  
Long Non Coding Rna

scholarly journals Methylation status of nc886 epiallele reflects periconceptional conditions and is associated with glucose metabolism through nc886 RNAs

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Saara Marttila ◽  
Leena E. Viiri ◽  
Pashupati P. Mishra ◽  
Brigitte Kühnel ◽  
Pamela R. Matias-Garcia ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Methylation Status ◽  
Induced Pluripotent Stem Cell ◽  
Methylation Pattern ◽  
Rna Expression ◽  
Non Coding Rna ◽  
Mother’S Age ◽  
Induced Pluripotent ◽  
Metastable Epiallele

Abstract Background Non-coding RNA 886 (nc886) is coded from a maternally inherited metastable epiallele. We set out to investigate the determinants and dynamics of the methylation pattern at the nc886 epiallele and how this methylation status associates with nc886 RNA expression. Furthermore, we investigated the associations between the nc886 methylation status or the levels of nc886 RNAs and metabolic traits in the YFS and KORA cohorts. The association between nc886 epiallele methylation and RNA expression was also validated in induced pluripotent stem cell (iPSC) lines. Results We confirm that the methylation status of the nc886 epiallele is mostly binomial, with individuals displaying either a non- or hemi-methylated status, but we also describe intermediately and close to fully methylated individuals. We show that an individual’s methylation status is associated with the mother’s age and socioeconomic status, but not with the individual’s own genetics. Once established, the methylation status of the nc886 epiallele remains stable for at least 25 years. This methylation status is strongly associated with the levels of nc886 non-coding RNAs in serum, blood, and iPSC lines. In addition, nc886 methylation status associates with glucose and insulin levels during adolescence but not with the indicators of glucose metabolism or the incidence of type 2 diabetes in adulthood. However, the nc886-3p RNA levels also associate with glucose metabolism in adulthood. Conclusions These results indicate that nc886 metastable epiallele methylation is tuned by the periconceptional conditions and it associates with glucose metabolism through the expression of the ncRNAs coded in the epiallele region.

scholarly journals Characterization of long non-coding RNA expression profiles in lymph node metastasis of early-stage cervical cancer

2016 ◽  
Vol 35 (6) ◽  
pp. 3185-3197 ◽  
Author(s):  
CHUNLIANG SHANG ◽  
WENHUI ZHU ◽  
TIANYU LIU ◽  
WEI WANG ◽  
GUANGXIN HUANG ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Lymph Node ◽  
Early Stage ◽  
Expression Profiles ◽  
Rna Expression ◽  
Node Metastasis ◽  
Non Coding Rna ◽  
Early Stage Cervical Cancer ◽  
Long Non Coding Rna

Genome-wide analysis of long non-coding RNA expression profiles in keratinocytes from psoriasis skin

2021 ◽  
Author(s):  
Longlong Luo ◽  
Nupur khera ◽  
Andor Pivarcsi ◽  
Ankit Srivastava ◽  
Lorenzo Pasquali ◽  
...  
Keyword(s):  
Expression Profiles ◽  
Rna Expression ◽  
Genome Wide Analysis ◽  
Non Coding Rna ◽  
Genome Wide ◽  
Long Non Coding Rna
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