scholarly journals Neoadjuvant chemoradiation radiation dose levels for surgically resectable esophageal cancer: predictors of use and outcomes

2017 ◽  
Vol 31 (5) ◽  
Author(s):  
M Buckstein ◽  
R Rhome ◽  
M Ru ◽  
E Moshier
Keyword(s):  
Esophageal Cancer ◽  
Radiation Dose ◽  
Neoadjuvant Chemoradiation ◽  
Resectable Esophageal ◽  
Resectable Esophageal Cancer ◽  
Dose Levels

Practice patterns in the treatment of locally advanced resectable esophageal carcinoma: A national survey of Canadian thoracic surgeons.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e14695-e14695
Author(s):  
Gordon Buduhan
Keyword(s):  
Esophageal Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Practice Patterns ◽  
Locally Advanced ◽  
Neoadjuvant Chemoradiation ◽  
The Other ◽  
Insufficient Evidence ◽  
Canadian Association ◽  
Resectable Esophageal ◽  
Resectable Esophageal Cancer

e14695 Background: Many institutions have adopted a multimodality strategy for treating locally advanced resectable esophageal cancer including surgery, chemotherapy and radiation. While many neoadjuvant protocols have been studied, there is no well defined standard treatment. In order to determine current practices and clinician opinions regarding treatment of esophageal cancer, a survey study of practicing Canadian thoracic surgeons was performed. Methods: Members of the Canadian Association of Thoracic Surgeons were contacted by email; those who currently treat esophageal cancer were asked to complete an online survey. Three separate emails were sent to maximize participation. Results: The response rate was 54% (56 /104). Of the respondents, 85% exclusively practiced general thoracic surgery, 87% worked at a University-affiliated hospital. We presented a hypothetical patient with bulky, resectable distal esophageal adenocarcinoma with enlarged paraesophageal lymph nodes (T3N1M0). 54% stated that neoadjuvant chemoradiation followed by surgery was their institution’s treatment of choice, while 33% used neoadjuvant chemotherapy plus surgery. When asked to choose the best treatment for this patient based on available evidence, 33% chose neoadjuvant chemoradiation, 33% favored neoadjuvant chemotherapy, 31% were undecided. Regarding neoadjuvant chemotherapy vs. chemoradiation, 63% strongly agreed or agreed there was insufficient evidence to decide whether or not one treatment was superior to the other. 73% strongly agreed or agreed to support a future randomized trial of preoperative chemotherapy vs. preoperative chemoradiation for esophageal cancer patients. Conclusions: Most Canadian thoracic surgeons use either neoadjuvant chemotherapy or chemoradiation followed by surgery for locally advanced resectable esophageal cancer. There is wide variation in practice patterns with no clear standard approach. 63% feel there is insufficient evidence to decide whether or not one treatment is superior to the other, and the majority support a future trial of neoadjuvant chemotherapy vs. chemoradiation. A pilot study is being planned to determine feasibility.

Reduction of heart volume during neoadjuvant chemoradiation in patients with resectable esophageal cancer.

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. 4044-4044
Author(s):  
Nadia Haj Mohammad ◽  
Martijn Kamphuis ◽  
Maarten Hulshof ◽  
Mark van Berge Henegouwen ◽  
Jacques Bergman ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Neoadjuvant Chemoradiation ◽  
Heart Volume ◽  
Resectable Esophageal ◽  
Resectable Esophageal Cancer

scholarly journals Optimal radiation dosing in concurrent neoadjuvant chemoradiation for resectable esophageal cancer: a meta-analysis

2019 ◽  
Vol 10 (3) ◽  
pp. 391-399
Author(s):  
Steven Engel ◽  
Adam Awerbuch ◽  
Deukwoo Kwon ◽  
Omar Picado ◽  
Raphael Yechieli ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Meta Analysis ◽  
Neoadjuvant Chemoradiation ◽  
Resectable Esophageal ◽  
Resectable Esophageal Cancer ◽  
Radiation Dosing

Reduction of heart volume during neoadjuvant chemoradiation in patients with resectable esophageal cancer

2015 ◽  
Vol 114 (1) ◽  
pp. 91-95 ◽  
Author(s):  
Nadia Haj Mohammad ◽  
Martijn Kamphuis ◽  
Maarten C.C.M. Hulshof ◽  
Lotte J. Lutkenhaus ◽  
Suzanne S. Gisbertz ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Neoadjuvant Chemoradiation ◽  
Heart Volume ◽  
Resectable Esophageal ◽  
Resectable Esophageal Cancer
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