Breast Cancer Diagnosis Using Multi-Stage Weight Adjustment In The MLP Neural Network

2020 ◽  
Author(s):  
Amin Rezaeipanah ◽  
Gholamreza Ahmadi

Abstract Breast cancer is the most common kind of cancer, which is the cause of death among the women worldwide. There is evidence that shows that the early detection and treatment can increase the survival rate of patients who suffered this disease. Therefore, this paper proposes an automatic breast cancer diagnosis technique using a genetic algorithm for simultaneous feature selection and parameter optimization of an Multi Layer Perceptron (MLP) neural network. The aim of this paper is to propose a hybrid classification algorithm based on Multi-stage Weights Adjustment in the MLP (MWAMLP) neural network in two parts to improve the breast cancer diagnosis. In the first part, the three classifiers are trained simultaneously on the learning dataset. The output of the first part classifier together with the learning dataset is placed in a new dataset. This dataset uses a hybrid classifier method to model the mapping between the outputs of each ordinary classifier of the first part with real output labels. The proposed algorithm is implemented with three different variations of the backpropagation (BP) technique, namely the Levenberg–Marquardt, resilient BP and gradient descent with momentum for fine tuning of the weight of MLP neural network and their performances are compared. Interestingly, one of the proposed algorithms titled MWAMLP-RP produces the best and on average, 99.35% and 98.74% correct classification, respectively, on the Wisconsin Breast Cancer Database dataset, which is comparable with the obtained results from the methods titled GP-DLNN, GAANN and CAFS and other works found in the literature.

2019 ◽  
Vol 2019 ◽  
pp. 1-16 ◽  
Author(s):  
Lian Zou ◽  
Shaode Yu ◽  
Tiebao Meng ◽  
Zhicheng Zhang ◽  
Xiaokun Liang ◽  
...  

This study reviews the technique of convolutional neural network (CNN) applied in a specific field of mammographic breast cancer diagnosis (MBCD). It aims to provide several clues on how to use CNN for related tasks. MBCD is a long-standing problem, and massive computer-aided diagnosis models have been proposed. The models of CNN-based MBCD can be broadly categorized into three groups. One is to design shallow or to modify existing models to decrease the time cost as well as the number of instances for training; another is to make the best use of a pretrained CNN by transfer learning and fine-tuning; the third is to take advantage of CNN models for feature extraction, and the differentiation of malignant lesions from benign ones is fulfilled by using machine learning classifiers. This study enrolls peer-reviewed journal publications and presents technical details and pros and cons of each model. Furthermore, the findings, challenges and limitations are summarized and some clues on the future work are also given. Conclusively, CNN-based MBCD is at its early stage, and there is still a long way ahead in achieving the ultimate goal of using deep learning tools to facilitate clinical practice. This review benefits scientific researchers, industrial engineers, and those who are devoted to intelligent cancer diagnosis.


2021 ◽  
Vol 24 (67) ◽  
pp. 147-156
Author(s):  
Amin Rezaeipanah ◽  
Neda Boroumand

Nowadays, breast cancer is one of the leading causes of death women in the worldwide. If breast cancer is detected at the beginning stage, it can ensure long-term survival. Numerous methods have been proposed for the early prediction of this cancer, however, efforts are still ongoing given the importance of the problem. Artificial Neural Networks (ANN) have been established as some of the most dominant machine learning algorithms, where they are very popular for prediction and classification work. In this paper, an Intelligent Ensemble Classification method based on Multi-Layer Perceptron neural network (IEC-MLP) is proposed for breast cancer diagnosis. The proposed method is split into two stages, parameters optimization and ensemble classification. In the first stage, the MLP Neural Network (MLP-NN) parameters, including optimal features, hidden layers, hidden nodes and weights, are optimized with an Evolutionary Algorithm (EA) for maximize the classification accuracy. In the second stage, an ensemble classification algorithm of MLP-NN is applied to classify the patient with optimized parameters. Our proposed IEC-MLP method which can not only help to reduce the complexity of MLP-NN and effectively selection the optimal feature subset, but it can also obtain the minimum misclassification cost. The classification results were evaluated using the IEC-MLP for different breast cancer datasets and the prediction results obtained were very promising (98.74% accuracy on the WBCD dataset). Meanwhile, the proposed method outperforms the GAANN and CAFS algorithms and other state-of-the-art classifiers. In addition, IEC-MLP could also be applied to other cancer diagnosis.


2016 ◽  
pp. 203-214 ◽  
Author(s):  
Ahmad Al-Khasawneh

Breast cancer is the second leading cause of cancer deaths in women worldwide. Early diagnosis of this illness can increase the chances of long-term survival of cancerous patients. To help in this aid, computerized breast cancer diagnosis systems are being developed. Machine learning algorithms and data mining techniques play a central role in the diagnosis. This paper describes neural network based approaches to breast cancer diagnosis. The aim of this research is to investigate and compare the performance of supervised and unsupervised neural networks in diagnosing breast cancer. A multilayer perceptron has been implemented as a supervised neural network and a self-organizing map as an unsupervised one. Both models were simulated using a variety of parameters and tested using several combinations of those parameters in independent experiments. It was concluded that the multilayer perceptron neural network outperforms Kohonen's self-organizing maps in diagnosing breast cancer even with small data sets.


Author(s):  
Ahmad Al-Khasawneh

Breast cancer is the second leading cause of cancer deaths in women worldwide. Early diagnosis of this illness can increase the chances of long-term survival of cancerous patients. To help in this aid, computerized breast cancer diagnosis systems are being developed. Machine learning algorithms and data mining techniques play a central role in the diagnosis. This paper describes neural network based approaches to breast cancer diagnosis. The aim of this research is to investigate and compare the performance of supervised and unsupervised neural networks in diagnosing breast cancer. A multilayer perceptron has been implemented as a supervised neural network and a self-organizing map as an unsupervised one. Both models were simulated using a variety of parameters and tested using several combinations of those parameters in independent experiments. It was concluded that the multilayer perceptron neural network outperforms Kohonen's self-organizing maps in diagnosing breast cancer even with small data sets.


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