scholarly journals Persistence of Nasopharyngeal Pneumococcal Vaccine Serotypes and Increase of Nonvaccine Serotypes Among Vaccinated Infants and Their Mothers 5 Years After Introduction of Pneumococcal Conjugate Vaccine 13 in The Gambia

2018 ◽  
Vol 68 (9) ◽  
pp. 1512-1521 ◽  
Author(s):  
Effua Usuf ◽  
Christian Bottomley ◽  
Ebrima Bojang ◽  
Isatou Cox ◽  
Abdoulie Bojang ◽  
...  
Keyword(s):  
Conjugate Vaccine ◽  
Pneumococcal Vaccine ◽  
Pneumococcal Conjugate Vaccine ◽  
The Gambia ◽  
Vaccine Serotypes

scholarly journals Etiology of Bacterial Meningitis Among Children <5 Years Old in Côte d’Ivoire: Findings of Hospital-based Surveillance Before and After Pneumococcal Conjugate Vaccine Introduction

2019 ◽  
Vol 69 (Supplement_2) ◽  
pp. S114-S120 ◽  
Author(s):  
Catherine Boni-Cisse ◽  
Sheikh Jarju ◽  
Rowan E Bancroft ◽  
Nicaise A Lepri ◽  
Hamidou Kone ◽  
...  
Keyword(s):  
Bacterial Meningitis ◽  
Conjugate Vaccine ◽  
Cote D'ivoire ◽  
Pneumococcal Conjugate Vaccine ◽  
Côte D’Ivoire ◽  
Type B ◽  
Cote D’Ivoire ◽  
Vaccine Serotypes ◽  
Vaccine Introduction ◽  
Côte D'ivoire

Abstract Background Bacterial meningitis remains a major disease affecting children in Côte d’Ivoire. Thus, with support from the World Health Organization (WHO), Côte d’Ivoire has implemented pediatric bacterial meningitis (PBM) surveillance at 2 sentinel hospitals in Abidjan, targeting the main causes of PBM: Streptococcus pneumoniae (pneumococcus), Haemophilus influenzae, and Neisseria meningitidis (meningococcus). Herein we describe the epidemiological characteristics of PBM observed in Côte d’Ivoire during 2010–2016. Methods Cerebrospinal fluid (CSF) was collected from children aged <5 years admitted to the Abobo General Hospital or University Hospital Center Yopougon with suspected meningitis. Microbiology and polymerase chain reaction (PCR) techniques were used to detect the presence of pathogens in CSF. Where possible, serotyping/grouping was performed to determine the specific causative agents. Results Overall, 2762 cases of suspected meningitis were reported, with CSF from 39.2% (1083/2762) of patients analyzed at the WHO regional reference laboratory in The Gambia. In total, 82 (3.0% [82/2762]) CSF samples were positive for bacterial meningitis. Pneumococcus was the main pathogen responsible for PBM, accounting for 69.5% (52/82) of positive cases. Pneumococcal conjugate vaccine serotypes 5, 18C, 19F, and 6A/B were identified post–vaccine introduction. Emergence of H. influenzae nontypeable meningitis was observed after H. influenzae type b vaccine introduction. Conclusions Despite widespread use and high coverage of conjugate vaccines, pneumococcal vaccine serotypes and H. influenzae type b remain associated with bacterial meningitis among children aged <5 years in Côte d’Ivoire. This reinforces the need for enhanced surveillance for vaccine-preventable diseases to determine the prevalence of bacterial meningitis and vaccine impact across the country.

First Otitis Media and Pneumococcal Conjugate Vaccine Serotypes in Infants

2018 ◽  
Vol 37 (12) ◽  
pp. e351-e352 ◽  
Author(s):  
Ron Dagan ◽  
Stephen Pelton ◽  
Lauren Bakaletz ◽  
Robert Cohen
Keyword(s):  
Otitis Media ◽  
Conjugate Vaccine ◽  
Pneumococcal Conjugate Vaccine ◽  
Vaccine Serotypes

Costs of vaccine delivery in the Gambia before and after, pentavalent and pneumococcal conjugate vaccine introductions

Vaccine ◽  
2014 ◽  
Vol 32 (17) ◽  
pp. 1975-1981 ◽  
Author(s):  
E. Usuf ◽  
G. Mackenzie ◽  
Y. Lowe-Jallow ◽  
B. Boye ◽  
D. Atherly ◽  
...  
Keyword(s):  
Conjugate Vaccine ◽  
Pneumococcal Conjugate Vaccine ◽  
Vaccine Delivery ◽  
The Gambia ◽  
Before And After

scholarly journals Colonization with 19F and other pneumococcal conjugate vaccine serotypes in children in St. Louis, Missouri, USA

Vaccine ◽  
2017 ◽  
Vol 35 (34) ◽  
pp. 4389-4395 ◽  
Author(s):  
Michelle McFarland ◽  
Taylor P. Szasz ◽  
Julie Y. Zhou ◽  
Kara Motley ◽  
Janardan S. Sivapalan ◽  
...  
Keyword(s):  
Conjugate Vaccine ◽  
Pneumococcal Conjugate Vaccine ◽  
Vaccine Serotypes
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