scholarly journals Phase 1 Safety and Pharmacokinetics Study of MK-2048/Vicriviroc (MK-4176)/MK-2048A Intravaginal Rings

2018 ◽  
Vol 68 (7) ◽  
pp. 1136-1143 ◽  
Author(s):  
Craig J Hoesley ◽  
Beatrice A Chen ◽  
Peter L Anderson ◽  
Charlene S Dezzutti ◽  
Julie Strizki ◽  
...  
Keyword(s):  
Phase 1 ◽  
Intravaginal Rings ◽  
Pharmacokinetics Study

scholarly journals Phase 1, open‐label, dose escalation, safety, and pharmacokinetics study of ME‐344 as a single agent in patients with refractory solid tumors

Cancer ◽  
2014 ◽  
Vol 121 (7) ◽  
pp. 1056-1063 ◽  
Author(s):  
Johanna C. Bendell ◽  
Manish R. Patel ◽  
Jeffrey R. Infante ◽  
Carla D. Kurkjian ◽  
Suzanne F. Jones ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Dose Escalation ◽  
Phase 1 ◽  
Single Agent ◽  
Open Label ◽  
Pharmacokinetics Study ◽  
Label Dose

Treatment with PF-04449913, an oral smoothened antagonist, in patients with myeloid malignancies: a phase 1 safety and pharmacokinetics study

2015 ◽  
Vol 2 (8) ◽  
pp. e339-e346 ◽  
Author(s):  
Giovanni Martinelli ◽  
Vivian G Oehler ◽  
Cristina Papayannidis ◽  
Rachel Courtney ◽  
M Naveed Shaik ◽  
...  
Keyword(s):  
Phase 1 ◽  
Myeloid Malignancies ◽  
Pharmacokinetics Study

scholarly journals Phase 1 Pharmacokinetic Trial of 2 Intravaginal Rings Containing Different Dose Strengths of Vicriviroc (MK-4176) and MK-2048

2018 ◽  
Vol 68 (7) ◽  
pp. 1129-1135 ◽  
Author(s):  
Albert Y Liu ◽  
Jingyang Zhang ◽  
Peter L Anderson ◽  
Theresa Wagner ◽  
Zhenyu Pan ◽  
...  
Keyword(s):  
Phase 1 ◽  
Intravaginal Rings

Rationalization and internalization

2001 ◽  
Vol 60 (4) ◽  
pp. 215-230 ◽  
Author(s):  
Jean-Léon Beauvois
Keyword(s):  
Phase 1 ◽  
Facilitatory Effect ◽  
Phase 2 ◽  
Causal Explanations ◽  
Reduction Effect ◽  
Dissonance Reduction

After having been told they were free to accept or refuse, pupils aged 6–7 and 10–11 (tested individually) were led to agree to taste a soup that looked disgusting (phase 1: initial counter-motivational obligation). Before tasting the soup, they had to state what they thought about it. A week later, they were asked whether they wanted to try out some new needles that had supposedly been invented to make vaccinations less painful. Agreement or refusal to try was noted, along with the size of the needle chosen in case of agreement (phase 2: act generalization). The main findings included (1) a strong dissonance reduction effect in phase 1, especially for the younger children (rationalization), (2) a generalization effect in phase 2 (foot-in-the-door effect), and (3) a facilitatory effect on generalization of internal causal explanations about the initial agreement. The results are discussed in relation to the distinction between rationalization and internalization.

Phase 1: In the Beginning

2004 ◽  
Author(s):  
Carl L. Henderson
Keyword(s):  
Phase 1 ◽  
In The Beginning
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