scholarly journals Incomplete Recovery of CD4 Cell Count, CD4 Percentage, and CD4/CD8 Ratio in Patients With Human Immunodeficiency Virus Infection and Suppressed Viremia During Long-term Antiretroviral Therapy

2018 ◽  
Vol 67 (6) ◽  
pp. 927-933 ◽  
Author(s):  
Yoshikazu Mutoh ◽  
Takeshi Nishijima ◽  
Yosuke Inaba ◽  
Noriko Tanaka ◽  
Yoshimi Kikuchi ◽  
...  
2009 ◽  
Vol 37 (3) ◽  
pp. 164-169 ◽  
Author(s):  
Adilha Misson Rua Micheletti ◽  
Valéria de Freitas Dutra ◽  
Eddie Fernando Cândido Murta ◽  
Marina Carvalho Paschoini ◽  
Mário Leon Silva-Vergara ◽  
...  

2017 ◽  
Vol 67 (2) ◽  
pp. 123-129
Author(s):  
Wipawee Nittayananta ◽  
Aree Kanjanaprapas ◽  
Pratanporn Arirachakaran ◽  
Kanokporn Pangsomboon ◽  
Hutcha Sriplung

2010 ◽  
Vol 29 (10) ◽  
pp. 966-968 ◽  
Author(s):  
Jurai Wongsawat ◽  
Thanyawee Puthanakit ◽  
Suparat Kanjanavanit ◽  
Rawiwan Hansudewechakul ◽  
Chaiwat Ngampiyaskul ◽  
...  

Author(s):  
Chioma P. Nnamaniv ◽  
Nkiru N. Ezeama ◽  
Owulo Agada ◽  
Paul N. Obiegbu ◽  
Kenechi O. Nnamani

Objective: Anaemia is a significant complication of human immunodeficiency infection, causing life-threatening symptoms and impairing quality of life. This study aimed to assess the prevalence, severity and associations of anaemia, with cluster of differentiation 4 (CD4+) cell count and use of highly active antiretroviral therapy (HAART), in human immunodeficiency virus-infected patients. Material and Methods: Haemoglobin concentration, CD4+ count, HAART use and other factors were assessed in 372, adult HIV-infected out-patients; enrolled at a tertiary hospital in South-Eastern Nigeria. Anaemia was defined according to World Health Organisation criteria. Independent predictors were determined using bivariate analysis and enter method logistic regression analysis, at a p-value<0.05.Results: Prevalence of anaemia was 76.3% overall; 79.9% in females and 67.6% in males. Median CD4+ cell count was 609.50 (interquartile range 379) cells per microlitre (cells/μl). Females were more likely to be anaemic than males [odds ratio (OR)=1.88, 95% confidence interval (CI) 1.07, 3.31; p-value=0.011]. Furthermore, the odds of being anaemic were higher in participants 50 years or older (OR 3.79, 95% CI 1.36, 10.55; p-value=0.023). A CD4+ count <200 cells/μl. Not being on cotrimoxazole preventive therapy and a low monthly household income were associated with higher odds of anaemia. Tenofovir- and abacavir-based regimens were associated with lower odds of anaemia compared to zidovudine. Conclusion: Gender and the age of patients were independent predictors of anaemia. Pre-treatment screening, and close follow-up monitoring for anaemia as well as increased access to less haematotoxic HAART regimens are needed.


2021 ◽  
Vol 2021 (3) ◽  
Author(s):  
Manish Soneja ◽  
Anivita Aggarwal ◽  
Parul Kodan ◽  
Nitin Gupta

Abstract We report a case of advanced human immunodeficiency virus (HIV) infection with multiple opportunistic infections (Pneumocystis carinii pneumonia, cryptosporidiosis, oesophagal candidiasis and cytomegalovirus infection). The patient was presumed to be adherent on antiretroviral therapy (ART) and was initiated on respective treatments for the opportunistic infections but continued to deteriorate. On further reviewing, he was found to be poorly adherent to ART and was advised enhanced adherence counselling after which his condition improved. We report this case to emphasize the importance of adherence to ART medications in the management of patients with HIV.


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