scholarly journals Prevalence of Human Papillomavirus, Human Immunodeficiency Virus, and Other Sexually Transmitted Infections Among Men Who Have Sex With Men in Togo: A National Cross-sectional Survey

2018 ◽  
Vol 69 (6) ◽  
pp. 1019-1026 ◽  
Author(s):  
Valentine Marie Ferré ◽  
Fifonsi A Gbeasor-Komlanvi ◽  
Gilles Collin ◽  
Anoumou Claver Dagnra ◽  
Quentin Le Hingrat ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Papillomavirus ◽  
Sub Saharan Africa ◽  
National Study ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Sexually Transmitted ◽  
Increased Risk ◽  
Immunodeficiency Virus ◽  
Sex With Men

Abstract Background Sub-Saharan Africa is a region of both high human immunodeficiency virus (HIV) and anal cancer incidence. We conducted the first national study in Togo to assess human papillomavirus (HPV), HIV, and other sexually transmitted infection (STI) prevalence among men who have sex with men (MSM). Methods A multicentric cross-sectional study was conducted among MSM recruited in 4 Togolese cities. Anal swabs were collected to test HPV, herpes simplex virus (HSV), and 7 STIs. Results Among the 207 MSM, HIV and high-risk HPV (hrHPV) overall prevalence were 26.1% and 44.9%, respectively. The most common hrHPV types were HPV-35 (15.0%) and HPV-16 (13.0%). Prevalence of hrHPV and multiple HPV infections were higher among HIV-infected than among HIV-uninfected MSM (85.2% vs 30.7%, P < 10–5 and 85.2% vs 28.7%, P < 10–5, respectively). Other STIs, except hepatitis B virus, were also more prevalent among HIV-infected MSM (Neisseria gonorrhoeae, P = .03; Mycoplasma genitalium, P = .04; HSV-2, P = .001; and a trend for Chlamydia trachomatis, P = .06). In multivariate analysis (adjusted odds ratio [95% confidence interval]), HIV (10.1 [4.0–25.6]), living in Lomé (2.8 [1.1–7.1]), HSV-2 excretion (26.7 [2.9–244.3]), C. trachomatis (11.7 [2.3–58.9]), and M. genitalium infection (9.6 [3.1–29.9]) were associated with increased risk of hrHPV infection. Conclusions We report a high burden of anal STIs with an unusual hrHPV type distribution among MSM, highlighting the critical need of implementation of a national strategy regarding prevention of STIs and vaccination against HPV.

scholarly journals GAMBARAN SIKAP PENCEGAHAN HIV/AIDS PADA KARYAWAN

2019 ◽  
Vol 2 (2) ◽  
pp. 83
Author(s):  
Liya Muzdalifah ◽  
Triana Arisdiani ◽  
Hermanto Hermanto
Keyword(s):  
Human Immunodeficiency Virus ◽  
Aids Prevention ◽  
Total Sample ◽  
Deficiency Syndrome ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Purposive Sampling ◽  
Sexually Transmitted ◽  
Immunodeficiency Virus ◽  
Hiv Aids

AIDS  atau Acquired Immuno Deficiency Syndrome adalah IMS (infeksi menular seksual) viral yang berkembang dari infeksi HIV atau Human Immunodeficiency Virus. HIV/AIDS telah mencapai proporsi epidemik diseluruh dunia. Kasus HIV/AIDS merupakan fenomena gunung es, dengan jumlah orang yang dilaporkan jauh lebih sedikit dibandingkan dengan kejadian yang sesungguhnya. Hal ini terlihat dari jumlah kasus AIDS yang dilaporkan setiap tahunnya yang sangat meningkat secara signifikan. Diperkirakan terdapat sekitar 630.000 ODHA di Indonesia pada tahun 2015. Penelitian bertujuan ini untuk mengetahui gambaran sikap pencegahan HIV/AIDS pada karyawan di Desa Sidorejo. Penelitian deskriptif dengan metode cross sectional. Jumlah sampel sebanyak 263 responden dengan menggunakan purposive sampling. Penelitian ini didapatkan hasil sebagian besar responden memiliki sikap baik tentang HIV/AIDS sebanyak 228 orang atau 86,7%. Penelitian selanjutnya diharapkan dapat dapat digunakan sebagai dasar awal untuk melanjutkan penelitian dibidang sama dengan variabel penelitian lain yang belum diungkap sehingga didapatkan hasil informasi yang lebih luas dan lengkap. Kata kunci : Sikap, HIV/AIDS, karyawan DESCRIPTION OF HIV / AIDS PREVENTION ATTITUDE IN EMPLOYEES ABSTRACTAIDS or Acquired Immuno Deficiency Syndrome is a viral sexually transmitted infection that develops from HIV infection or the Human Immunodeficiency Virus. HIV / AIDS has reached epidemic proportions throughout the world. The case of HIV / AIDS is an iceberg phenomenon, with far fewer people reported compared to actual events. This can be seen from the number of AIDS cases reported each year which has increased significantly. It is estimated that there were around 630,000 PLWHA in Indonesia in 2015. The purpose of this study was to find a picture of HIV / AIDS prevention attitudes among employees in Desa Sidorejo. Descriptive research with cross sectional method. The total sample of 263 respondents using purposive sampling. This study found that the majority of respondents had good attitudes about HIV / AIDS as many as 228 people or 86.7%. Future studies are expected to be able to be used as an initial basis for continuing research in the same field as other research variables that have not been revealed so that the results obtained are more extensive and complete. Keywords: Attitudes, HIV / AIDS, employees

scholarly journals Extragenital Gonorrhoea in Men Who Have Sex with Men: A Retrospective Study in a STI Clinic in Lisbon, Portugal

2018 ◽  
Vol 31 (5) ◽  
pp. 247 ◽  
Author(s):  
Margarida Moura Valejo Coelho ◽  
Eugénia Matos-Pires ◽  
Vasco Serrão ◽  
Ana Rodrigues ◽  
Cândida Fernandes
Keyword(s):  
Human Immunodeficiency Virus ◽  
Retrospective Study ◽  
Neisseria Gonorrhoeae ◽  
Sexually Transmitted Infection ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Sexually Transmitted Infection Clinic ◽  
Immunodeficiency Virus ◽  
Sex With Men ◽  
Infection Clinic

Introduction: Recent studies worldwide reveal a significant prevalence of extragenital infections by Neisseria gonorrhoeae among men who have sex with men. We aimed to analyse the frequency and characteristics of extragenital gonococcal infections diagnosed in men who have sex with men in a walk-in Sexually Transmitted Infection clinic in Lisbon, Portugal.Material and Methods: We conducted a cross-sectional, retrospective study of the anorectal and/or oropharyngeal Neisseria gonorrhoeae infections in men who have sex with men, diagnosed in our Sexually Transmitted Infection clinic between January 2014 and December 2016.Results: We found extragenital infection in 87 cases of gonorrhoea identified in men who have sex with men in this period, including: 49 cases of anorectal disease, 9 of oropharyngeal disease, 13 cases of infection at both extragenital sites, and 16 of simultaneous extragenital and urogenital gonorrhoea. Patients’ ages ranged from 17 to 64 years (median: 28 years). Forty-seven (54%) of the patients did not present with any extragenital symptoms. Thirty (35%) were human immunodeficiency virus-1-positive.Discussion: Since most extragenital Neisseria gonorrhoeae infections are asymptomatic, they may be missed and go untreated unless actively investigated. Current international guidelines recommend the screening of gonorrhoea at extragenital sites in men who have sex with men because anorectal and oropharyngeal infections constitute a potential disease reservoir, and may facilitate transmission and/or acquisition of human immunodeficiency virus infection.Conclusion: Our results highlight the relevance of testing men who have sex with men for Neisseria gonorrhoeae at extragenital sites, regardless of the existence of local complaints. The implementation of adequate screening programmes in Portugal should be considered. We also reinforce the need to raise awareness in the population regarding the adoption of prophylactic measures against transmission of sexually transmitted infections during anal and/or oral sexual exposure.

scholarly journals Pilot study to introduce a notification card for partner notification of sexually transmitted infections in Catalonia, Spain, June 2010 to June 2011

2013 ◽  
Vol 18 (27) ◽  
Author(s):  
M J Tuneu ◽  
X Vallès ◽  
D Carnicer-Pont ◽  
M J Barberá ◽  
P Godoy ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Partner Notification ◽  
Cross Sectional Study ◽  
Sexual Partners ◽  
Chlamydia Infection ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Sexually Transmitted ◽  
Immunodeficiency Virus ◽  
Sex With Men

We conducted a cross-sectional study in 10 primary care centres in Catalonia, to determine applicability, acceptability and effectiveness of partner notification cards used by patients diagnosed of a sexually transmitted infection (STI) and to characterise these and their sexual partners. Statutorily notifiable STIs included Chlamydia infection, gonorrhoea, syphilis, human immunodeficiency virus (HIV) infection or other STIs as deemed necessary by the treating physician. Between June 2010 and June 2011, 219 index cases were enrolled, of whom 130 were men (59.4%), 71 of them men who have sex with men (54.6%). Chlamydia infection (41.1%), gonorrhoea (17.8%) and syphilis (16.0%) were the STIs most frequently diagnosed. HIV infection accounted for 4% of cases. A total of 687 sexual partners were reported, and 300 of these were traceable through the notification card (45.7%). Those who did not report traceable contacts were older (mean age: 34 years versus 31 years, p=0.03). The main reason for not distributing the card was anonymous sexual intercourse (38%). Patient referral notification cards can reach a high percentage of sexual partners at risk. However, only few notified sexual partners attended participating health centres. Internet-based partner notification may be considered in order to reach those partners not otherwise traceable.

scholarly journals Human Immunodeficiency Virus (HIV)-Negative Men Who Have Sex With Men Have Higher CD8+ T-Cell Counts and Lower CD4+/CD8+ T-Cell Ratios Compared With HIV-Negative Heterosexual Men

2020 ◽  
Author(s):  
Sebastiaan O Verboeket ◽  
Ferdinand W Wit ◽  
Eveline Verheij ◽  
Rosan A van Zoest ◽  
Neeltje A Kootstra ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cell ◽  
Cd8 T Cell ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Cell Counts ◽  
Immunodeficiency Virus ◽  
Sex With Men ◽  
Use Behavior ◽  
Hiv Negative

Abstract Background We previously reported T-cell senescence to be similar in people with human immunodeficiency virus (PWH) with suppressed viremia (predominantly men who have sex with men [MSM]) and human immunodeficiency virus (HIV)-negative otherwise comparable controls but greater than in healthy blood donors. This led us to compare CD4+ and CD8+ T-cell counts and CD4+/CD8+ ratios between HIV-negative MSM and men who only have sex with women (MSW) and relate observed differences in behavioral factors and infectious exposures, including cytomegalovirus (CMV) infection. Methods In 368 HIV-negative MSM and 72 HIV-negative MSW, T lymphocyte phenotyping was performed 3 times biennially. Baseline CMV serology and sexually transmitted infection (STI) incidence and/or STI seroprevalence, sexual, and substance-use behavior data were collected during study visits. Results Men who have sex with men, compared with MSW, had higher CD8+ counts (551 vs 437 cells/mm3, P &lt; .001), similar CD4+ counts (864 vs 880 cells/mm3, P = .5), and lower CD4+/CD8+ ratios (1.84 vs 2.47, P &lt; .001). Differences were most pronounced for MSM with &gt;10 recent sex partners and partly explained by higher CMV seroprevalence in MSM. Conclusions These findings suggest that factors other than HIV may, in both PWH and certain HIV-negative MSM, contribute to a low CD4+/CD8+ ratio. Whether this, like in PWH, contributes to comorbidity risk in HIV-negative MSM requires further study.

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