scholarly journals ‘Fight Antibiotic Resistance—It’s in Your Hands’: Call From the World Health Organization for 5th May 2017

2017 ◽  
Vol 64 (12) ◽  
pp. 1780-1783 ◽  
Author(s):  
Daniela Pires ◽  
Marlieke Elizabeth Adriana de Kraker ◽  
Ermira Tartari ◽  
Mohamed Abbas ◽  
Didier Pittet
Keyword(s):  
Antibiotic Resistance ◽  
World Health Organization ◽  
World Health ◽  
The World ◽  
Health Organization

scholarly journals Evaluation of Emerging Antimicrobials Resistance in Nosocomial Infections Caused by E. Coli: The Comparison Results of Observed Cases and Compartmental Model

2021 ◽  
Author(s):  
Mahshid Nasehi ◽  
Babak Eshrati ◽  
Hamidreza Baradaran ◽  
Leila Janani ◽  
Sasan Ghorbani-Kalkhajeh ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Antimicrobial Resistance ◽  
World Health Organization ◽  
Nosocomial Infections ◽  
World Health ◽  
Antibiotic Resistant ◽  
Microbial Resistance ◽  
E Coli ◽  
The World ◽  
Health Organization

Abstract Background: The World Health Organization repeatedly emphasizes the spread and association of nosocomial infections with microbial resistance. In a 2014 report, the World Health Organization cited microbial resistance as a global threat. In recent years, the world has seen the rapid growth of antibiotic-resistant E. coli in most areas, which poses a serious threat to public health. A high percentage of bacteria that cause nosocomial infections have been resistant to treatment. The most common bacterial agent among these nosocomial infections is E. coli. This bacterium is one of the main causes of nosocomial infections among hospitalized patients. One of the most important goals of the Global Antimicrobial Resistance and Use Surveillance System (GLASS) is timely identification and transmission of Emerging Antimicrobial Resistance (EAR) or outbreak of antibiotic resistance. One of the main ways to identify this "emerging" at the national or local level is to identify deviations from the expected resistance in drug compounds. As a result, if the observed cases of a drug-resistant pathogen are significantly higher than expected, it could indicate "emerging".Purpose: This study aimed to identify and transmit EAR or outbreak of antibiotic resistance among antibiotics used in the treatment of nosocomial infections caused by E. coli. This was done by comparing the observed cases of resistant E. coli with the predicted cases of resistant E. coli, which were predicted by the compartment model.Methods: This is a hospital-based study that used data from the nosocomial infection survelliance system to investigate observed cases of antibiotic resistance. In this study, the results of 12,954 antibiogram tests related to 57 hospitals located in 31 provinces of Iran were divided into two parts (results related to the first half of 2017 and results related to the second half of 2017). The model was developed in the second half of the year to predict expected cases. Before developeing model to predict the expected cases of resistant E. coli, the validity of the model was evaluated by implementing the model in the first half of the year. Finally, the predicted cases of resistant E. coli were compared with those observed in 2017. If the difference between the two was statistically significant, it indicated the outbreak of E.coli. This model evaluated 11 antibiotics recommended by the World Health Organization that are used to treat nosocomial infections caused by E. coli.Results: The results of this study showed that the outbreak of E. coli resistant to ampicillin and ceftazidime occurred in 2017 in hospitals of Iran. This means that resistance to ampicillin and ceftazidime antibiotics in nosocomial infections caused by E. coli is higher than expected and has become "emerging".Conclusion: This study showed how the outbreak of antibiotic resistance in the country's hospitals can be investigated. Using the method of this study, we can investigate the outbreak of antibiotic-resistant E. coli in the coming years and in different substrates. The results of this study showed that the administration and use of antibiotics should be reconsidered.

scholarly journals Evaluation of Emerging Antimicrobials Resistance in Nosocomial Infections Caused by E. Coli: the Comparison Results of Observed Cases and Compartmental Model

2021 ◽  
Author(s):  
Mahshid Nasehi ◽  
Babak Eshrati ◽  
Hamid Reza Baradaran ◽  
Leila Janani ◽  
Sasan Ghorbani Kalkhajeh ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Antimicrobial Resistance ◽  
World Health Organization ◽  
Nosocomial Infections ◽  
World Health ◽  
Antibiotic Resistant ◽  
Microbial Resistance ◽  
E Coli ◽  
The World ◽  
Health Organization

Abstract Background: The World Health Organization repeatedly emphasizes the spread and association of nosocomial infections with microbial resistance. In a 2014 report, the World Health Organization cited microbial resistance as a global threat. In recent years, the world has seen the rapid growth of antibiotic-resistant E. coli in most areas, which poses a serious threat to public health. A high percentage of bacteria that cause nosocomial infections have been resistant to treatment. The most common bacterial agent among these nosocomial infections is E. coli. This bacterium is one of the main causes of nosocomial infections among hospitalized patients. One of the most important goals of the Global Antimicrobial Resistance and Use Surveillance System (GLASS) is timely identification and transmission of Emerging Antimicrobial Resistance (EAR) or outbreak of antibiotic resistance. One of the main ways to identify this "emerging" at the national or local level is to identify deviations from the expected resistance in drug compounds. As a result, if the observed cases of a drug-resistant pathogen are significantly higher than expected, it could indicate "emerging".Purpose: This study aimed to identify and transmit EAR or outbreak of antibiotic resistance among antibiotics used in the treatment of nosocomial infections caused by E. coli. This was done by comparing the observed cases of resistant E. coli with the predicted cases of resistant E. coli, which were predicted by the compartment model.Methods: This is a hospital-based study that used data from the nosocomial infection survelliance system to investigate observed cases of antibiotic resistance. In this study, the results of 12,954 antibiogram tests related to 57 hospitals located in 31 provinces of Iran were divided into two parts (results related to the first half of 2017 and results related to the second half of 2017). The model was developed in the second half of the year to predict expected cases. Before developeing model to predict the expected cases of resistant E. coli, the validity of the model was evaluated by implementing the model in the first half of the year. Finally, the predicted cases of resistant E. coli were compared with those observed in 2017. If the difference between the two was statistically significant, it indicated the outbreak of E.coli. This model evaluated 11 antibiotics recommended by the World Health Organization that are used to treat nosocomial infections caused by E. coli.Results: The results of this study showed that the outbreak of E. coli resistant to ampicillin and ceftazidime occurred in 2017 in hospitals of Iran. This means that resistance to ampicillin and ceftazidime antibiotics in nosocomial infections caused by E. coli is higher than expected and has become "emerging".Conclusion: This study showed how the outbreak of antibiotic resistance in the country's hospitals can be investigated. Using the method of this study, we can investigate the outbreak of antibiotic-resistant E. coli in the coming years and in different substrates. The results of this study showed that the administration and use of antibiotics should be reconsidered.

scholarly journals Whole-Genome Sequencing of Pathogenic Bacteria—New Insights into Antibiotic Resistance Spreading

2021 ◽  
Vol 9 (12) ◽  
pp. 2624
Author(s):  
Andrey Shelenkov
Keyword(s):  
Antibiotic Resistance ◽  
Antimicrobial Resistance ◽  
World Health Organization ◽  
Genome Sequencing ◽  
Pathogenic Bacteria ◽  
World Health ◽  
Whole Genome ◽  
Opportunistic Bacteria ◽  
The World ◽  
Health Organization

In recent years, the acquisition of antimicrobial resistance (AMR) by both pathogenic and opportunistic bacteria has become a major problem worldwide, which was already noticed as a global healthcare threat by the World Health Organization [...]

scholarly journals Antibiotic Resistance in Malaysia, and its Public Health Implications

2019 ◽  
Vol 9 (2) ◽  
pp. 534-541
Author(s):  
A.M. Meer Ahmad
Keyword(s):  
Public Health ◽  
Antibiotic Resistance ◽  
World Health Organization ◽  
World Health ◽  
Health Awareness ◽  
Health Implications ◽  
The Us ◽  
The World ◽  
Health Organization ◽  
Hospital Acquired

The World Health Organization (WHO) notes high-rates of resistance among bacteria associated with common illness in all the WHO-regions - both hospital-acquired and community-acquired (WHO 2014). An estimated 2 million cases of antibiotic-resistance are reported in the US annually, causing 23,000 deaths. With reference to such, the US CDC states that about 30% of the total-annual 150 million prescriptions for antibiotics is not justified. There is a need for greater prudence in the use involving joint-efforts in surveillance, public health awareness additionally, and in formulating clear policies on procurement and prudent use. Keywords: Antibiotic Resistance, Public Health, prescriptions

scholarly journals Uji Resistensi Terhadap Beberapa Antibiotika pada Escherichia coli yang Diisolasi dari Kucing di Klinik Hewan Kota Bogor

2020 ◽  
Vol 7 (3) ◽  
pp. 203
Author(s):  
Yamin Yaddi ◽  
Safika Safika ◽  
Fachriyan Hasmi Pasaribu
Keyword(s):  
Escherichia Coli ◽  
Antibiotic Resistance ◽  
World Health Organization ◽  
Animal Health ◽  
World Health Organisation ◽  
World Health ◽  
Health Concern ◽  
Resistance To Antibiotics ◽  
The World ◽  
Health Organization

ABSTRAKPermasalahan resistensi Antibiotika pada hewan kesayangan menjadi kendala kesehatan hewan di seluruh dunia. World Health Organisation (WHO) menyebutkan bahwa pada masa mendatang resistensi antibiotika akan menjadi tantangan yang terbesar dalam dunia kesehatan. Penelitian ini bertujuan untuk mengukur tingkat resistensi antibiotika terhadap Escherichia coli yang diisolasi dari kucing pada klinik hewan di Kota Bogor. Hasil penelitian menunjukan bahwa resistensi Escherichia coli tertinggi terjadi pada golongan β-laktam (ampisilin 66% dan amoksisilin 60%) yang diikuti oleh golongan tetrasiklin (oksitetrasiklin 54% dan dosisiklin 24%), serta golongan kuinolon (enrofloksasin 38% dan ciprofloksasin 28%). Hasil dari penelitian ini diharapkan dapat menjadi pertimbangan medis bagi praktisi hewan kesayangan dalam penggunaan antibiotika.Kata Kunci: Escherichia coli, klinik hewan, kucing, resistensi antibiotikaABSTRACTThe problem of antibiotic resistance in pets is obstacles to animal health throughout the world. World Health Organization (WHO) states that in the future, antibiotic resistance will become the biggest challenge in the health concern. This study aims to measure the level of Escherichia coli resistance to antibiotics which is isolated from cats on veterinary clinics in Bogor City. The results showed that the highest resistance of Escherichia coli occurred in the β-lactam group (ampicillin 66% and amoxicillin 60%) followed by tetracycline (oxytetracycline 54% and doxycycline 24%), and quinolone group (enrofloxacin 38% and ciprofloxacin 28%). This study is expected to become medical considerations for pet practitioners in the use of antibiotics.Keywords: animal clinic, antibiotic resistance, cats, Escherichia coli

Erstes Instrument zur standardisierten Erfassung der Teilhabe Behinderter

2017 ◽  
Vol 79 (07) ◽  
pp. 526-527
Keyword(s):  
World Health Organization ◽  
World Health ◽  
The World ◽  
Health Organization ◽  
Menschen Mit Behinderung

Coenen M et al. [Recommendation for the collection and analysis of data on participation and disability from the perspective of the World Health Organization]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2016; 59: 1060–1067 Um eine gleichberechtigte Teilhabe an der Gesellschaft von Menschen mit Behinderung zu ermöglichen, werden zunächst Daten zu vorhandenen Einschränkungen gebraucht. Erst wenn diese detailliert erhoben wurden, können Konzepte zur Beseitigung von Problemen entwickelt werden. Ein standardisiertes Erhebungsinstrument für alle Aspekte der Funktionsfähigkeit fehlte jedoch bisher.

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