scholarly journals MRSA Transmission Dynamics Among Interconnected Acute, Intermediate-Term, and Long-Term Healthcare Facilities in Singapore

2017 ◽  
Vol 64 (suppl_2) ◽  
pp. S76-S81 ◽  
Author(s):  
Angela Chow ◽  
Vanessa W Lim ◽  
Ateeb Khan ◽  
Kerry Pettigrew ◽  
David C. B. Lye ◽  
...  
Keyword(s):  
Transmission Dynamics ◽  
Healthcare Facilities

Discharge of pharmaceuticals into municipal sewers from hospitals and long-term care facilities

2012 ◽  
Vol 47 (2) ◽  
pp. 140-152 ◽  
Author(s):  
Muhammad Riaz ul Haq ◽  
Chris Metcalfe ◽  
Hongxia Li ◽  
Wayne Parker
Keyword(s):  
Long Term Care ◽  
Treatment Plant ◽  
Biological Response ◽  
Care Homes ◽  
Pharmaceutically Active Compounds ◽  
Term Care ◽  
Healthcare Facilities ◽  
Antibiotic Compounds ◽  
Composite Samples

The presence of pharmaceutically active compounds in the aquatic environment has become well established, and their presence is of potential concern because they are designed to produce biological response in the target receptor, may bear intrinsic toxicity (e.g. cytostatic agents, antibiotics) and they possess the potential to foster and maintain drug resistance. For both risk assessment and risk management purposes, it is important to identify the major sources of pharmaceuticals in the environment. Healthcare facilities may be major sources of the discharges of these compounds into municipal sewers. In this study, we investigated the contributions to the wastewater treatment plant (WWTP) influents from two hospitals and two long-term care homes of nine compounds. Twenty-four hour composite samples were collected over 5 consecutive days from the effluents of these facilities. The WWTPs receiving sewage from these facilities were also sampled on the same days to facilitate mass balance calculations. The results showed that the healthcare facilities contributed a greater proportion of the antibiotic compounds to the WWTPs than the other target compounds; with maximum contributions of ciprofloxacin by hospitals and long-term care homes of 26.7 and 37%, respectively.

Modelled evaluation of multi-component meningococcal vaccine (Bexsero®) for the prevention of invasive meningococcal disease in infants and adolescents in the UK

2013 ◽  
Vol 142 (9) ◽  
pp. 2000-2012 ◽  
Author(s):  
J. HUELS ◽  
K. M. CLEMENTS ◽  
L. J. McGARRY ◽  
G. J. HILL ◽  
J. WASSIL ◽  
...  
Keyword(s):  
Meningococcal Disease ◽  
Standard Care ◽  
Demographic Data ◽  
Time Frame ◽  
Transmission Dynamics ◽  
Transmission Model ◽  
Meningococcal Vaccine ◽  
Catch Up ◽  
The Uk

SUMMARYNeisseria meningitidis is the main cause of bacterial meningitis and sepsis in the UK, and can potentially be lethal or cause long-term sequelae. Bexsero® (4CMenB) is a new multi-component vaccine approved by the European Commission for use in individuals aged ⩾2 months. A theoretical transmission model was constructed to assess the long-term effectiveness of Bexsero compared to standard care. The model was populated with UK-specific demographic data and calibrated to ensure that the transmission dynamics of meningococcal disease in the UK were adequately simulated. The model showed the best strategy to be a routine vaccination programme at ages 2, 3, 4, 12 months and 14 years combined with a 5-year catch-up programme in toddlers aged 12–24 months and adolescents aged 15–18 years. This would lead to a 94% reduction in meningococcal cases or 150 000 cases and 15 000 deaths over a 100-year time-frame.

scholarly journals Addressing the quality and scope of paediatric primary care in South Africa: Evaluating contextual impacts of the introduction of the Practical Approach to Care Kit for children (PACK Child)

2020 ◽  
Author(s):  
Jamie Murdoch ◽  
Robyn Curran ◽  
Ruth Cornick ◽  
Sandy Picken ◽  
Max Bachmann ◽  
...  
Keyword(s):  
South Africa ◽  
Primary Care ◽  
Primary Healthcare ◽  
Routine Care ◽  
Health Systems Strengthening ◽  
Psychosocial Issues ◽  
Healthcare Facilities ◽  
Contextual Features ◽  
Child Intervention

Abstract Background: Despite significant reductions in mortality, preventable and treatable conditions remain leading causes of death and illness in children in South Africa. The PACK Child intervention, comprising clinical decision support tool (guide), training strategy and health systems strengthening components, was developed to expand on WHO’s Integrated Management of Childhood Illness programme, extending care of children under 5 years to those aged 0-13 years, those with chronic conditions needing regular follow-up, integration of curative and preventive measures and routine care of the well child. In 2017-2018, PACK Child was piloted in 10 primary healthcare facilities in the Western Cape Province. Here we report findings from an investigation into the contextual features of South African primary care that shaped how clinicians delivered the PACK Child intervention within clinical consultations.Methods: Process evaluation using linguistic ethnographic methodology which provides analytical tools for investigating human behaviour, and the shifting meaning of talk and text within context. Methods included semi-structured interviews, focus groups, ethnographic observation, audio-recorded consultations and documentary analysis. Analysis focused on how mapped contextual features structured clinician-caregiver interactions. Results: Primary healthcare facilities demonstrated an institutionalised orientation to minimising risk upheld by provincial documentation, providing curative episodic care to children presenting with acute symptoms, and preventive care including immunisations, feeding and growth monitoring, all in children 5 years or younger. Children with chronic illnesses such as asthma rarely receive routine care. These contextual features constrained the ability of clinicians to use the PACK Child guide to facilitate diagnosis of long-term conditions, elicit and manage psychosocial issues, and navigate use of the guide alongside provincial documentation. Conclusion: Our findings provide evidence that PACK Child is catalysing a transition to an approach that strikes a balance between assessing and minimising risk on the day of acute presentation and a larger remit of care for children over time. However, optimising success of the intervention requires reviewing priorities for paediatric care which will facilitate enhanced skills, knowledge and deployment of clinical staff to better address acute illnesses and long-term health conditions of children of all ages, as well as complex psychosocial issues surrounding the child.

scholarly journals The effect of heterogeneous infectious period and contagiousness on the dynamics ofSalmonellatransmission in dairy cattle

2008 ◽  
Vol 136 (11) ◽  
pp. 1496-1510 ◽  
Author(s):  
C. LANZAS ◽  
S. BRIEN ◽  
R. IVANEK ◽  
Y. LO ◽  
P. P. CHAPAGAIN ◽  
...  
Keyword(s):  
Dairy Cattle ◽  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Transmission Dynamics ◽  
Infectious Period ◽  
Specific Group ◽  
Infection Transmission ◽  
Force Of Infection ◽  
The Impact

SUMMARYThe objective of this study was to address the impact of heterogeneity of infectious period and contagiousness onSalmonellatransmission dynamics in dairy cattle populations. We developed three deterministic SIR-type models with two basic infected stages (clinically and subclinically infected). In addition, model 2 included long-term shedders, which were defined as individuals with low contagiousness but long infectious period, and model 3 included super-shedders (individuals with high contagiousness and long infectious period). The simulated dynamics, basic reproduction number (R0) and critical vaccination threshold were studied. Clinically infected individuals were the main force of infection transmission for models 1 and 2. Long-term shedders had a small impact on the transmission of the infection and on the estimated vaccination thresholds. The presence of super-shedders increasesR0and decreases the effectiveness of population-wise strategies to reduce infection, making necessary the application of strategies that target this specific group.

Device-related infections in long-term healthcare facilities: the challenge of prevention

2014 ◽  
Vol 9 (4) ◽  
pp. 487-495 ◽  
Author(s):  
Nico T Mutters ◽  
Frank Günther ◽  
Alexandra Heininger ◽  
Uwe Frank
Keyword(s):  
Healthcare Facilities

Transmission dynamics of Cryptosporidium in primates and herbivores at the Barcelona zoo: a long-term study

2002 ◽  
Vol 104 (1) ◽  
pp. 19-26 ◽  
Author(s):  
M Gracenea ◽  
M.S Gómez ◽  
J Torres ◽  
E Carné ◽  
J Fernández-Morán
Keyword(s):  
Transmission Dynamics ◽  
Term Study ◽  
Long Term Study

scholarly journals Fistula as a Public Health challenge in Pakistan

2018 ◽  
Vol 13 (2) ◽  
Author(s):  
Shamoon Noushad ◽  
Shershah Syed ◽  
Sadaf Ahmed
Keyword(s):  
Public Health ◽  
Obstetric Fistula ◽  
Secondary Data ◽  
Health Interventions ◽  
Public Health Interventions ◽  
Healthcare Facilities ◽  
Public Health Challenge ◽  
Effective Public Health ◽  
The Impact

Aims: To explore the impact of obstetric fistula in the county and to propose effective public health interventions that can help to prevent the condition with a long-term goal of eradicating the condition. Methods: The survey and analysis included secondary data addressing women's experiences of fistula; dynamics and limitationsdetermining women's access to in healthcare facilities for fistula management; and restraintsof health professional as well as health inequities. Results: It was assessed that recently, many hospitals and organizations in the country go on board on intercessions to address the impact of the illness, however, much importance is on pinpointing and discussing the existing cases rather than focusing on public health interventions that can help to prevent and eventually eradicate the condition in Pakistan.

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