scholarly journals Editorial Commentary: Toward New Tools to Assess Rare Invasive Fungal Diseases in Critically Ill Patients

2016 ◽  
Vol 63 (10) ◽  
pp. 1318-1319
Author(s):  
Julien Textoris ◽  
Javier Yugueros-Marcos ◽  
Françoise Gay-Andrieu
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Fungal Diseases ◽  
Editorial Commentary ◽  
Invasive Fungal Diseases

scholarly journals Performance of Existing Definitions and Tests for the Diagnosis of Invasive Fungal Diseases other than Invasive Candidiasis and Invasive Aspergillosis in Critically Ill, Adult Patients: A Systematic Review with Qualitative Evidence Synthesis

2021 ◽  
Vol 7 (3) ◽  
pp. 176
Author(s):  
Daniele Giacobbe ◽  
Andrea Cortegiani ◽  
Ilias Karaiskos ◽  
Toine Mercier ◽  
Sofia Tejada ◽  
...  
Keyword(s):  
At Risk ◽  
Invasive Aspergillosis ◽  
Critically Ill ◽  
Systematic Reviews ◽  
Invasive Candidiasis ◽  
Fungal Diseases ◽  
Adult Patients ◽  
Qualitative Evidence Synthesis ◽  
Invasive Fungal Diseases ◽  
Populations At Risk

The Fungal Infections Definitions in Intensive Care Unit (ICU) patients (FUNDICU) project aims to provide standard sets of definitions for invasive fungal diseases (IFDs) in critically ill, adult patients, including invasive aspergillosis (IA), invasive candidiasis (IC), Pneumocystis jirovecii pneumonia (PJP), and other non-IA, non-IC IFDs. The first step of the project was the conduction of separated systematic reviews of the characteristics and applicability to critically ill, adult patients outside classical populations at risk (hematology patients, solid organ transplant recipients) of available definitions and diagnostic tests for IFDs. We report here the results of two systematic reviews exploring the performance of available definitions and tests, for PJP and for other non-IA, non-IC IFDs. Starting from 2585 and 4584 records for PJP and other IFDs, respectively, 89 and 61 studies were deemed as eligible for full-text evaluation. However, only two studies for PJP and no studies for other IFDs met the FUNDICU protocol criteria for inclusion in qualitative synthesis. Currently, there is no sufficient solid data for directly evaluating the performance of existing definitions and laboratory tests for the diagnosis of PJP and other non-IA, non-IC IFDs in critically ill adult patients outside classical populations at risk.

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