scholarly journals Home Screening for Bacterial Vaginosis to Prevent Sexually Transmitted Diseases

2015 ◽  
Vol 62 (5) ◽  
pp. 531-536 ◽  
Author(s):  
Jane R. Schwebke ◽  
Jeannette Y. Lee ◽  
Shelly Lensing ◽  
Susan S. Philip ◽  
Harold C. Wiesenfeld ◽  
...  
Keyword(s):  
Bacterial Vaginosis ◽  
Sexually Transmitted Diseases ◽  
Sexually Transmitted

Can bacterial vaginosis help to find sexually transmitted diseases, especially chlamydial cervicitis?

2009 ◽  
Vol 20 (2) ◽  
pp. 108-111 ◽  
Author(s):  
K Yoshimura ◽  
M Yoshimura ◽  
T Kobayashi ◽  
T Kubo ◽  
T Hachisuga ◽  
...  
Keyword(s):  
Bacterial Vaginosis ◽  
Sexually Transmitted Diseases ◽  
Sexually Transmitted

Coinfection with chlamydia and gonorrhoea among pregnant women with bacterial vaginosis

1996 ◽  
Vol 7 (1) ◽  
pp. 61-64 ◽  
Author(s):  
M. R. Joesoef ◽  
G. Wiknjosastro ◽  
W. Norojono ◽  
H. Sumampouw ◽  
M. Linnan ◽  
...  
Keyword(s):  
Bacterial Vaginosis ◽  
Pregnant Women ◽  
Sexually Transmitted Diseases ◽  
Economic Status ◽  
Sexual Transmission ◽  
Fold Increase ◽  
Gram Stain ◽  
Sexually Transmitted ◽  
Socio Economic Status

The role of sexual transmission of microorganisms in bacterial vaginosis (BV) is controversial. If sexual intercourse were a risk factor for BV, then we would expect that women with BV would also be coinfected with other sexually transmitted diseases (STD). We investigated the prevalence of STD among pregnant women of low socio-economic status with bacterial vaginosis in Indonesia. Among these women, 23.3% had at least one STD (chlamydia, gonorrhoea, syphilis or trichomoniasis). Chlamydial infection was the most prevalent (19.5%), followed by trichomoniasis (3.8%), gonorrhoea (3.2%) and syphilis (0.4%). Compared to the rates of STD observed in a previous study of all pregnant women (with or without BV) in Indonesia, pregnant women with BV have more than a 2-fold increase in chlamydia (19.5% vs 8.2%) and a 6-fold increase in gonorrhoea (3.2% vs 0.5%). Because detection of BV by Gram stain is easy to perform and economical, detection of BV has potential as a prescreening marker for chlamydia and gonorrhoea among asymptomatic pregnant women of low socio-economic status in Indonesia. Further work is needed to evaluate the usefulness of BV as a prescreening marker for chlamydia and gonorrhoea.

scholarly journals Findings Associated with Recurrence of Bacterial Vaginosis among Adolescents Attending Sexually Transmitted Diseases Clinics

2007 ◽  
Vol 20 (4) ◽  
pp. 225-231 ◽  
Author(s):  
Rebecca M. Brotman ◽  
Emily J. Erbelding ◽  
Roxanne M. Jamshidi ◽  
Mark A. Klebanoff ◽  
Jonathan M. Zenilman ◽  
...  
Keyword(s):  
Bacterial Vaginosis ◽  
Sexually Transmitted Diseases ◽  
Sexually Transmitted

scholarly journals Reversible Deficiency of Antimicrobial Polypeptides in Bacterial Vaginosis

2006 ◽  
Vol 74 (10) ◽  
pp. 5693-5702 ◽  
Author(s):  
Erika V. Valore ◽  
Dorothy J. Wiley ◽  
Tomas Ganz
Keyword(s):  
Bacterial Vaginosis ◽  
Sexually Transmitted Diseases ◽  
Lavage Fluid ◽  
Vulvovaginal Candidiasis ◽  
Gardnerella Vaginalis ◽  
Vaginal Fluid ◽  
Sexually Transmitted ◽  
Lactobacillus Jensenii ◽  
Increased Risk ◽  
Antimicrobial Polypeptides

ABSTRACT Bacterial vaginosis is a common condition associated with increased risk of sexually transmitted diseases, including human immunodeficiency virus infections. In contrast, vulvovaginal candidiasis has a much weaker association with sexually transmitted diseases. We found that vaginal lavage fluid from women with bacterial vaginosis is deficient in antimicrobial polypeptides and antimicrobial activity compared to fluid from healthy women or women with vulvovaginal candidiasis. Effective treatment normalized the concentrations of antimicrobial polypeptides in both bacterial vaginosis and in vulvovaginal candidiasis, suggesting that the abnormalities were a result of the diseases. Unlike in vulvovaginal candidiasis, the neutrophil attractant chemokine interleukin-8 (IL-8) was not increased in bacterial vaginosis, accounting for low concentrations of neutrophil-derived defensins in vaginal fluid. In organotypic cultures of human vaginal epithelium containing dendritic cells, treatment with Lactobacillus jensenii, a typical vaginal resident, induced the synthesis of IL-8 mRNA and the epithelial human β-defensin-2 mRNA, but a typical bacterial vaginosis pathogen, Gardnerella vaginalis, had no effect. When the two bacteria were combined, Gardnerella vaginalis did not interfere with the immunostimulatory effect of Lactobacillus jensenii. The loss of normal immunostimulatory flora in bacterial vaginosis is thus associated with a local deficiency of multiple innate immune factors, and this deficiency could predispose individuals to sexually transmitted diseases.

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