scholarly journals Tolerance of Benznidazole in a United States Chagas Disease Clinic

2015 ◽  
Vol 60 (8) ◽  
pp. 1237-1240 ◽  
Author(s):  
D. A. Miller ◽  
S. Hernandez ◽  
L. Rodriguez De Armas ◽  
S. J. Eells ◽  
M. M. Traina ◽  
...  
Keyword(s):  
United States ◽  
Chagas Disease ◽  
Disease Clinic

scholarly journals Current knowledge of Chagas-related heart disease among pediatric cardiologists in the United States

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sanchi Malhotra ◽  
Imran Masood ◽  
Noberto Giglio ◽  
Jay D. Pruetz ◽  
Pia S. Pannaraj
Keyword(s):  
United States ◽  
Differential Diagnosis ◽  
Heart Disease ◽  
Chagas Disease ◽  
Latin American ◽  
Current Knowledge ◽  
Parasitic Infection ◽  
The United States ◽  
Cardiac Complications ◽  
The U.S

Abstract Background Chagas disease is a pathogenic parasitic infection with approximately 8 million cases worldwide and greater than 300,000 cases in the United States (U.S.). Chagas disease can lead to chronic cardiomyopathy and cardiac complications, with variable cardiac presentations in pediatrics making it difficult to recognize. The purpose of our study is to better understand current knowledge and experience with Chagas related heart disease among pediatric cardiologists in the U.S. Methods We prospectively disseminated a 19-question survey to pediatric cardiologists via 3 pediatric cardiology listservs. The survey included questions about demographics, Chagas disease presentation and experience. Results Of 139 responses, 119 cardiologists treat pediatric patients in the U.S. and were included. Most providers (87%) had not seen a case of Chagas disease in their practice; however, 72% also had never tested for it. The majority of knowledge-based questions about Chagas disease cardiac presentations were answered incorrectly, and 85% of providers expressed discomfort with recognizing cardiac presentations in children. Most respondents selected that they would not include Chagas disease on their differential diagnosis for presentations such as conduction anomalies, myocarditis and/or apical aneurysms, but would be more likely to include it if found in a Latin American immigrant. Of respondents, 87% agreed that they would be likely to attend a Chagas disease-related lecture. Conclusions Pediatric cardiologists in the U.S. have seen very few cases of Chagas disease, albeit most have not sent testing or included it in their differential diagnosis. Most individuals agreed that education on Chagas disease would be worth-while.

Prognostic impact of Chagas disease in the United States

2009 ◽  
Vol 157 (1) ◽  
pp. 22-29 ◽  
Author(s):  
José Milei ◽  
Roberto Andrés Guerri-Guttenberg ◽  
Daniel Rodolfo Grana ◽  
Rubén Storino
Keyword(s):  
United States ◽  
Chagas Disease ◽  
The United States ◽  
Prognostic Impact

Fernandis, Sarah A. Collins

2013 ◽  
Author(s):  
Wilma Peebles-Wilkins
Keyword(s):  
Public Health ◽  
United States ◽  
Venereal Disease ◽  
Health Department ◽  
The United States ◽  
Black Communities ◽  
Disease Clinic ◽  
Social Settlement ◽  
Civic Leader ◽  
The City

Sarah Fernandis (1863–1951) was a civic leader and organizer of public health activities in Black communities. She founded the first black social settlement in the United States. In 1920, she became the first Black social worker employed in the City Venereal Disease Clinic of the Baltimore Health Department.

scholarly journals Chagas Disease Serological Test Performance in U.S. Blood Donor Specimens

2019 ◽  
Vol 57 (12) ◽  
Author(s):  
Jeffrey D. Whitman ◽  
Christina A. Bulman ◽  
Emma L. Gunderson ◽  
Amanda M. Irish ◽  
Rebecca L. Townsend ◽  
...  
Keyword(s):  
United States ◽  
South America ◽  
Central America ◽  
Chagas Disease ◽  
Blood Donor ◽  
Test Performance ◽  
Chronic Phase ◽  
High Specificity ◽  
The United States ◽  
Confirmatory Test

ABSTRACT Chagas disease affects an estimated 300,000 individuals in the United States. Diagnosis in the chronic phase requires positive results from two different IgG serological tests. Three enzyme-linked immunosorbent assays (ELISAs) (Hemagen, Ortho, and Wiener) and one rapid test (InBios) are FDA cleared, but comparative data in U.S. populations are sparse. We evaluated 500 seropositive and 300 seronegative blood donor plasma samples. Country of birth was known for 255 seropositive specimens, which were grouped into regions as follows: Mexico (n = 94), Central America (n = 88), and South America (n = 73). Specimens were tested by the four FDA-cleared IgG serological assays. Test performance was evaluated by two comparators and latent class analysis. InBios had the highest sensitivity (97.4% to 99.3%) but the lowest specificity (87.5% to 92.3%). Hemagen had the lowest sensitivity (88.0% to 92.0%) but high specificity (99.0% to 100.0%). The level of sensitivity was intermediate for Ortho (92.4% to 96.5%) and Wiener (94.0% to 97.1%); both had high specificity (98.8% to 100.0% and 96.7% to 99.3%, respectively). The levels of antibody reactivity and clinical sensitivity were lowest in donors from Mexico, intermediate in those from Central America, and highest in those from South America. Our findings provide an initial evidence base to improve laboratory diagnosis of Chagas disease in the United States. The best current testing algorithm would employ a high-sensitivity screening test followed by a high-specificity confirmatory test.

scholarly journals Trends and associated characteristics for Chagas disease among women of reproductive age in the United States, 2002 to 2017

2020 ◽  
Vol 11 ◽  
pp. e00167
Author(s):  
Chioma Ikedionwu ◽  
Deepa Dongarwar ◽  
Manvir Kaur ◽  
Lisa Nunez ◽  
Annabella Awazi ◽  
...  
Keyword(s):  
United States ◽  
Chagas Disease ◽  
The United States ◽  
Reproductive Age ◽  
Women Of Reproductive Age

scholarly journals Proposed multidimensional framework for understanding Chagas disease healthcare barriers in the United States

2019 ◽  
Vol 13 (9) ◽  
pp. e0007447 ◽  
Author(s):  
Colin Forsyth ◽  
Sheba Meymandi ◽  
Ilan Moss ◽  
Jason Cone ◽  
Rachel Cohen ◽  
...  
Keyword(s):  
United States ◽  
Chagas Disease ◽  
The United States ◽  
Healthcare Barriers

Chagas' disease in the United States

1992 ◽  
Vol 123 (6) ◽  
pp. 1724 ◽  
Author(s):  
Pedro A. Reyes
Keyword(s):  
United States ◽  
Chagas Disease ◽  
The United States
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