scholarly journals Plasma Fluoride Level as a Predictor of Voriconazole-Induced Periostitis in Patients With Skeletal Pain

2014 ◽  
Vol 59 (9) ◽  
pp. 1237-1245 ◽  
Author(s):  
Woo J. Moon ◽  
Erica L. Scheller ◽  
Anupam Suneja ◽  
Jacob A. Livermore ◽  
Anurag N. Malani ◽  
...  
Keyword(s):  
2013 ◽  
Author(s):  
Khulood Hussein ◽  
Hanan Alkadi ◽  
Suzan Lanham-New ◽  
Mohamad Ardawi

Foods ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1265
Author(s):  
Marc H. G. Berntssen ◽  
Lars Thoresen ◽  
Sissel Albrektsen ◽  
Eduardo Grimaldo ◽  
Leif Grimsmo ◽  
...  

Aquaculture produces most of the world’s seafood and is a valuable food source for an increasing global population. Low trophic mesopelagic biomasses have the potential to sustainably supplement aquafeed demands for increased seafood production. The present study is a theoretical whole-chain feed and food safety assessment on ingredients from mesopelagic biomass and the resulting farmed fish fed these ingredients, based on analysis of processed mesopelagic biomass. Earlier theoretical estimations have indicated that several undesirable compounds (e.g., dioxins and metals and fluoride) would exceed the legal maximum levels for feed and food safety. Our measurements on processed mesopelagic biomasses show that only fluoride exceeds legal feed safety limits. Due to high levels of fluoride in crustaceans, their catch proportion will dictate the fluoride level in the whole biomass and can be highly variable. Processing factors are established that can be used to estimate the levels of undesirables in mesopelagic aquafeed ingredients from highly variable species biomass catches. Levels of most the studied undesirables (dioxins, PCBs, organochlorine pesticides, brominated flame retardant, metals, metalloids) were generally low compared to aquafeed ingredients based on pelagic fish. Using a feed-to-fillet aquaculture transfer model, the use of mesopelagic processed aquafeed ingredients was estimated to reduce the level of dioxins and PCBs by ~30% in farmed seafood such as Atlantic salmon.


PEDIATRICS ◽  
1987 ◽  
Vol 79 (4) ◽  
pp. 587-592
Author(s):  
Deborah C. ter Meulen ◽  
Massoud Majd

A retrospective analysis of bone scans of 381 children with unexplained skeletal pain was made. Of these, findings are reported on 358 for whom there were sufficient clinical data. The bone scan results suggested trauma as the cause of pain in 43 patients, inflammatory disease in 73 patients, and neoplasia in ten patients. There was only one false-positive bone scan. Normal findings were obtained from 227 patients, in whom no significant skeletal disease was detected on follow-up, except for juvenile rheumatoid arthritis in 23 patients. Bone scintigraphy is, therefore, an important, noninvasive diagnostic test for evaluating children with obscure bone or joint pain. We recommend that this test be performed early in the evaluation of these children to arrive at the diagnosis expeditiously and with minimal patient discomfort and morbidity.


JAMA ◽  
1952 ◽  
Vol 150 (8) ◽  
pp. 785 ◽  
Author(s):  
Eugene F. Traut
Keyword(s):  

2020 ◽  
Vol 3 (1) ◽  

Background: Thoracic ossification of ligamentum flavum (OLF) caused by skeletal fluorosis is rare [1]. Only six patients had been reported in the English literature. This study is the second study to the best of our knowledge in literature. Aims and Objectives: To evaluate the causation of ossification of ligamentum flavum due to fluorosis in accordance with reports from the first clinical series of this disease. Exact etiopathogenesis of thoracic ossification of yellow ligament is not known and causation due to fluorosis is rare, so this study was hypothesized [2]. Materials and Methods: This is a prospective study of patients with thoracic OLF due to skeletal fluorosis who underwent surgical management at the NIMS hospital between 2017 and 2018. A total of 16 cases were enrolled, (56.25%), 9 males and 7 (43.75%) females, age ranging from 37 to 62 years (mean 50.5 years). Imaging showed OLF together with ossification of interosseous membranes, including interosseous membranes of the forearm (14/16 patients 87.5%).Urinalysis showed a markedly high urinary fluoride level in 15 of 16 patients (93.75%).Ossified ligamentum flavum sent for estimation of fluoride levels in 16 patients showed high fluoride level in the bone ash prepared from the oyl in 15 patients and other structures sent as control were ,spinous process ,interspinous ligaments didn’t show any fluoride deposition. Results: Out of 16 patient 15 patient had fluoride levels more than 6000mg/kg, 7 patient had values between 6,000 – 7,000 mg/kg, 5 patient had values between 7,500 – 9,000 mg/kg and 3 patients had values > 8400 mg/kg. Controls were sent as spinous processes had normal fluoride level between 500-1000 mg/kg and interspinous ligaments sent showed no fluoride levels. Out of 16 patients 9 patients had multiple level dorsal OYL both contiguous and non-contiguous, contiguous in 4 patients and non – contiguous in 5 patients.7 patients had single level dorsal OYL. Most common segment involved in OYL is T9 and D10 level in 14 patients. Sato classification 6 were Type A, 5 were Type B, 3 were Type C, 2 were Type D Conclusion: This is the largest series of ossification of dorsal yellow ligament due to fluorosis. And consideration of fluorosis as one of the important etiological cause for OYL to be kept in mind and all patients with OYL to be screened for Fluorosis and this would also help as a preventive measure for the people around the surroundings of the affected person and would help the society from a crippling disability.


Bone Cancer ◽  
2010 ◽  
pp. 321-332
Author(s):  
Monica Herrera ◽  
Juan Miguel Jimenez-Andrade ◽  
Marina Vardanyan ◽  
Patrick W. Mantyh
Keyword(s):  

Author(s):  
Mahmood Yousefi ◽  
Farzaneh Asghari ◽  
Pietro Zuccarello ◽  
Gea Oliveri Conti ◽  
Aida Ejlali ◽  
...  

Prevalence of fluorosis is a worldwide public health issue, especially in the West Azerbaijan province of Iran. The aim of this study was to investigate fluoride concentration in drinking water resources within Maku city, in both the warm and cold seasons, to perform a health risk assessment. Fluoride were measured using UV-visible spectrophotometry. The spatial distribution was calculated by the software ArcGIS and Hazard Quotients (HQs) were calculated according to the US EPA method. The fluoride concentrations ranged between 0.29 to 6.68 and 0.1 to 11.4 mg/L in the cold and warm seasons, respectively. Based on this report, 30.64 and 48.15% of the samples revealed a fluoride level higher than the permissible level in the cold and warm seasons, respectively. Moreover, results showed that the HQ value in the warm season for different age groups was higher than the HQ value in the cold season. In both seasons, the non-carcinogenic risks of fluoride for the four exposed populations varied according to the order: children > teenagers > adults > infants. The HQ values for three age groups (children, teenager and adults) for both seasons were higher than 1 with a high risk of fluorosis. The results of this study, support the requests that government authorities better manage water supplies to improve health quality.


2019 ◽  
Vol 7 (19) ◽  
pp. 16355-16363 ◽  
Author(s):  
Animesh Halder ◽  
Soumendra Singh ◽  
Aniruddha Adhikari ◽  
Priya Singh ◽  
Probir Kumar Sarkar ◽  
...  

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