scholarly journals Antibiotic Prophylaxis for High-Risk Patients With Acute Q Fever: No Definitive Answers Yet

2013 ◽  
Vol 58 (3) ◽  
pp. 446-447 ◽  
Author(s):  
L. M. Kampschreur ◽  
J. J. Oosterheert ◽  
P. C. Wever ◽  
C. P. Bleeker-Rovers
Keyword(s):  
High Risk ◽  
Antibiotic Prophylaxis ◽  
Q Fever ◽  
High Risk Patients ◽  
Risk Patients ◽  
Acute Q Fever

scholarly journals Is extended preoperative antibiotic prophylaxis for high-risk patients necessary before percutaneous nephrolithotomy?

2016 ◽  
Vol 57 (6) ◽  
pp. 417 ◽  
Author(s):  
Aaron M. Potretzke ◽  
Alyssa M. Park ◽  
Tyler M. Bauman ◽  
Jeffrey A. Larson ◽  
Joel M. Vetter ◽  
...  
Keyword(s):  
High Risk ◽  
Antibiotic Prophylaxis ◽  
Percutaneous Nephrolithotomy ◽  
High Risk Patients ◽  
Preoperative Antibiotic Prophylaxis ◽  
Risk Patients

scholarly journals Extended Antibiotic Prophylaxis May Be Linked to Lower Peri-prosthetic Joint Infection Rates in High-Risk Patients: An Evidence-Based Review

2019 ◽  
Vol 15 (3) ◽  
pp. 297-301 ◽  
Author(s):  
Christopher J. DeFrancesco ◽  
Michael C. Fu ◽  
Cynthia A. Kahlenberg ◽  
Andy O. Miller ◽  
Mathias P. Bostrom
Keyword(s):  
High Risk ◽  
Antibiotic Prophylaxis ◽  
Prosthetic Joint Infection ◽  
Joint Infection ◽  
Evidence Based ◽  
Infection Rates ◽  
High Risk Patients ◽  
Prosthetic Joint ◽  
Risk Patients

scholarly journals A selective antibiotic prophylaxis policy for laparoscopic cholecystectomy is effective in minimising infective complications

2013 ◽  
Vol 95 (5) ◽  
pp. 345-348 ◽  
Author(s):  
F Yanni ◽  
P Mekhail ◽  
G Morris-Stiff
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Laparoscopic Cholecystectomy ◽  
High Risk ◽  
Antibiotic Prophylaxis ◽  
Gallstone Disease ◽  
Anaerobic Growth ◽  
Current Evidence ◽  
High Risk Patients ◽  
Risk Patients

Introduction It has been demonstrated previously that the identification of bactibilia during cholecystectomy is associated with the presence of one or more risk factors: acute cholecystitis, common duct stones, emergency surgery, intraoperative findings and age >70 years. Current evidence-based guidance on antibiotic prophylaxis during laparoscopic cholecystectomy (LC) is based on elective procedures and does not take into account these factors. The aim of this study was to assess the effectiveness of a selective antibiotic prophylaxis policy limited to high risk patients undergoing LC with the development of port site infections as the primary endpoint. Methods One hundred consecutive patients undergoing LC under the care of a single consultant surgeon during a one-year period were studied prospectively. Data collected included patient demographics (age, sex) as well as details of the history of gallstone disease to determine those with complex disease and risk factors for bactibilia. A single dose of antibiotics (second generation cephalosporin and metronidazole) was administered on induction to patients with a risk factor present. Information relating to all radiologically or microbiologically confirmed infections was documented. Results Eighty-four of the patients were female and the mean age was 47.7 ±16.0 years. Nineteen LCs were performed as emergencies and the remainder were elective procedures. A risk factor for bactibilia was present in 35 patients. A wound infection was identified in four cases, two of which were Staphylococcus aureus (one methicillin resistant), one was a coagulase negative Staphylococcus and one wound cultured a mixed anaerobic growth. Three of the infections occurred in patients receiving prophylaxis (2 staphylococcal and 1 anaerobic) at intervals of 7, 14 and 19 days respectively. One patient with a body mass index of 32kg/m2 in the ‘no prophylaxis’ group developed a coagulase negative staphylococcal infection at 10 days. No intra or extra-abdominal abdominal infections were identified. Conclusions This study has demonstrated that restricting antibiotic prophylaxis to high risk patients has no detrimental effects in terms of increasing the rate of infections in those with no risk factors. Furthermore, the act of not prescribing to low risk patients will limit costs and the risk of adverse events. It will also reduce the risk of resistance and clostridial infections in this cohort.

Implementation of a Q fever vaccination program for high-risk patients in the Netherlands

Vaccine ◽  
2013 ◽  
Vol 31 (23) ◽  
pp. 2617-2622 ◽  
Author(s):  
Leslie D. Isken ◽  
Marleen Kraaij-Dirkzwager ◽  
Patricia E. Vermeer-de Bondt ◽  
Hans C. Rümke ◽  
Clementine Wijkmans ◽  
...  
Keyword(s):  
High Risk ◽  
The Netherlands ◽  
Q Fever ◽  
Vaccination Program ◽  
High Risk Patients ◽  
Risk Patients

Prevention of infective endocarditis (IE)

2018 ◽  
pp. 127-130
Author(s):  
Abdullah Jibawi ◽  
Mohamed Baguneid ◽  
Arnab Bhowmick
Keyword(s):  
Infective Endocarditis ◽  
High Risk ◽  
Antibiotic Prophylaxis ◽  
High Risk Patients ◽  
Operative Site ◽  
Dental Patients ◽  
Risk Patients ◽  
Current Guidelines ◽  
Dental Work

Infective endocarditis is a serious condition due to bacteraemia resulting from interventions. Current guidelines suggested antibiotic prophylaxis should not be used for routine dental or non-dental patients even in high-risk patients. However, it should be considered for high-risk patients for interventional dental work and also in other circumstances if the operative site suspected to be infective and might result in bacteraemia in high-risk patients.

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