A Systematic Review and Meta-regression of Temporal Trends in Adult CD4+ Cell Count at Presentation to HIV Care, 1992-2011

2013 ◽  
Vol 57 (7) ◽  
pp. 1027-1037 ◽  
Author(s):  
C. R. Lesko ◽  
S. R. Cole ◽  
A. Zinski ◽  
C. Poole ◽  
M. J. Mugavero
Keyword(s):  
Systematic Review ◽  
Cell Count ◽  
Temporal Trends ◽  
Hiv Care ◽  
Cd4 Cell Count ◽  
Meta Regression ◽  
Cd4 Cell

scholarly journals CD4 Cell Count Threshold for Cryptococcal Antigen Screening of HIV-Infected Individuals: A Systematic Review and Meta-analysis

2018 ◽  
Vol 66 (suppl_2) ◽  
pp. S152-S159 ◽  
Author(s):  
Nathan Ford ◽  
Zara Shubber ◽  
Joseph N Jarvis ◽  
Tom Chiller ◽  
Greg Greene ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cell Count ◽  
Meta Analysis ◽  
Cd4 Cell Count ◽  
Cryptococcal Antigen ◽  
Cd4 Cell

Effect of Probiotic Supplementation on CD4 Cell Count in HIV-Infected Patients: A Systematic Review and Meta-analysis

2017 ◽  
Vol 15 (5) ◽  
pp. 776-788 ◽  
Author(s):  
Asma Kazemi ◽  
Kurosh Djafarian ◽  
John R. Speakman ◽  
Parviz Sabour ◽  
Sepideh Soltani ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cell Count ◽  
Meta Analysis ◽  
Probiotic Supplementation ◽  
Cd4 Cell Count ◽  
Cd4 Cell

scholarly journals The Continuing Value of CD4 Cell Count Monitoring for Differential HIV Care and Surveillance

10.2196/11136 ◽  
2019 ◽  
Vol 5 (1) ◽  
pp. e11136 ◽  
Author(s):  
Brian Rice ◽  
Andrew Boulle ◽  
Sandra Schwarcz ◽  
Amir Shroufi ◽  
George Rutherford ◽  
...  
Keyword(s):  
Cell Count ◽  
Hiv Care ◽  
Cd4 Cell Count ◽  
Cd4 Cell

scholarly journals Immediate Blood Draw for CD4+ Cell Count Is Associated with Linkage to Care in Durban, South Africa: Findings from Pathways to Engagement in HIV Care

PLoS ONE ◽  
2016 ◽  
Vol 11 (10) ◽  
pp. e0162085 ◽  
Author(s):  
Susie Hoffman ◽  
Theresa M. Exner ◽  
Naomi Lince-Deroche ◽  
Cheng-Shiun Leu ◽  
Jessica L. Phillip ◽  
...  
Keyword(s):  
South Africa ◽  
Cell Count ◽  
Linkage To Care ◽  
Hiv Care ◽  
Blood Draw ◽  
Cd4 Cell Count ◽  
Engagement In Hiv Care ◽  
Cd4 Cell

Late HIV presentation – missed opportunities and factors associated with a changing pattern over time

2016 ◽  
Vol 28 (8) ◽  
pp. 814-821 ◽  
Author(s):  
Sarah O’Connell ◽  
Julia Enkelmann ◽  
Corinna Sadlier ◽  
Colm Bergin
Keyword(s):  
Hiv Testing ◽  
Cell Count ◽  
Demographic Data ◽  
Hiv Care ◽  
Late Presenters ◽  
Cd4 Cell Count ◽  
Factors Associated ◽  
Cell Counts ◽  
Cd4 Cell ◽  
Over Time

Delayed diagnosis of HIV infection has negative clinical, economic and public health implications. The study primary aim was to identify factors associated with late HIV presentation (Late Presenters [LPS], CD4 cell count < 350 cells/mm3). A secondary aim was to identify changing trends of late HIV presentation from 2002 to 2014 at our centre. A retrospective cohort study was performed. Demographic data and CD4 cell count of new HIV diagnoses presenting to our ambulatory HIV service over four time-periods from 2002 to 2014 were recorded. Proportion of LPS and factors associated with late presentation were compared using Graphpad Instat. In 2014, of 231 new patients attending for HIV care, 75 (32.6%) were late presenters versus 146 (66.4%) in 2002. This indicates a decreasing proportion of LPS from 2002 to 2014. However, the proportion of those with CD4 cell counts <200 on presentation at these two time intervals remain unchanged. The overall proportion of male LPS has increased over time and the proportion of LPS in the men who have sex with men (MSM) cohort has decreased over time, reflecting increased frequency of both HIV testing and diagnoses in MSM in recent years. The proportion of heterosexual LPS has not changed significantly in the same time period and LPS were older in 2014 versus 2002. The proportion of LPS defined by CD4 cell count remains higher than is justifiable in an era of increased HIV testing and awareness. Further targets for HIV testing to decrease rates of LPS include non-traditional risk groups including heterosexual and older patient cohorts. LPS rates are lower than rates found internationally, and it is possible that consensus definition of LPS needs to be revised.

scholarly journals The HIV treatment cascade in people living with HIV in Iran in 2014: Mixed-method study to measure losses and reasons

2019 ◽  
Vol 30 (13) ◽  
pp. 1257-1264 ◽  
Author(s):  
Nima Ghalehkhani ◽  
Behnam Farhoudi ◽  
Mohammad Mehdi Gouya ◽  
Hamid Sharifi ◽  
SeyedAhmad SeyedAlinaghi ◽  
...  
Keyword(s):  
Cell Count ◽  
Hiv Treatment ◽  
Hiv Care ◽  
People Living With Hiv ◽  
Cd4 Cell Count ◽  
Treatment Cascade ◽  
Cascade Analysis ◽  
Hiv Treatment Cascade ◽  
Living With Hiv ◽  
Cd4 Cell

The study assessed the HIV treatment cascade of people living with HIV (PLWH) in Iran and the reasons for gaps in HIV services in 2014. We did the cascade analysis using the WHO HIV test–treat–retain cascade analysis tool (2014). To measure the gaps, we checked the records for all PLWH reported to the national HIV surveillance till September 2014 to define how many were alive, linked to HIV care, assessed for CD4 cell count, started antiretroviral therapy (ART), and reported to be alive up to five years after ART. To assess the reasons for gaps in the cascade, we ran desk review, four focus group discussions and 51 in-depth interviews with key informants including PLWH. Spectrum model estimated 75,700 PLWH in Iran, of whom only 22,647 people (%30) were diagnosed. Of those who were diagnosed with HIV, 16,266 people (%72) had enrolled in HIV care. About 13% of all PLWH were retained in HIV care and only 9% (6745 people) had ever been tested for CD4 cell count. Only 8% (6018 people) of all PLWH had received ART by September 2014. We found the biggest gap in the HIV treatment cascade to be HIV diagnosis as only 30% of PLWH have been diagnosed. Innovative strategies to improve HIV testing, particularly those that work best for key populations, are critical to reach the 90–90-90 targets.

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