scholarly journals The Immunomodulatory Nutritional Intervention NR100157 Reduced CD4+ T-Cell Decline and Immune Activation: A 1-Year Multicenter Randomized Controlled Double-Blind Trial in HIV-Infected Persons Not Receiving Antiretroviral Therapy (The BITE Study)

2013 ◽  
Vol 57 (1) ◽  
pp. 139-146 ◽  
Author(s):  
P. Cahn ◽  
K. Ruxrungtham ◽  
B. Gazzard ◽  
R.S. Diaz ◽  
A. Gori ◽  
...  
2017 ◽  
Vol 61 (12) ◽  
Author(s):  
Sergio Serrano-Villar ◽  
Giorgia Caruana ◽  
Alexander Zlotnik ◽  
José A. Pérez-Molina ◽  
Santiago Moreno

ABSTRACT A low CD4/CD8 ratio during treated HIV infection reflects heightened immune activation and predicts death. The effects of different antiretroviral therapy regimens on CD4/CD8 ratio recovery remains unclear. We performed a post hoc analysis of the MERIT study, a randomized, double-blind trial of maraviroc versus efavirenz in combination with zidovudine-lamivudine in treatment-naive HIV-infected individuals. We found higher rates of CD4/CD8 ratio normalization with efavirenz, which was driven by a greater CD8+ T-cell decline.


2009 ◽  
Vol 201 (6) ◽  
pp. S127-S128 ◽  
Author(s):  
Avi Harlev ◽  
Barak Aricha-Tamir ◽  
Roy Kessous ◽  
Savyona Ben Ayun ◽  
Arnon Wiznitzer ◽  
...  

2016 ◽  
Vol 194 ◽  
pp. 774-780 ◽  
Author(s):  
Yong-jun Ahn ◽  
Joon-Shik Shin ◽  
Jinho Lee ◽  
Yoon Jae Lee ◽  
Me-riong Kim ◽  
...  

2001 ◽  
Vol 18 (6) ◽  
pp. 389-393 ◽  
Author(s):  
U. R. Döpfmer ◽  
M. R. Schenk ◽  
S. Kuscic ◽  
D. H. Beck ◽  
S. Döpfmer ◽  
...  

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