scholarly journals HPLC/Fluorometric Detection of Carvedilol in Real Human Plasma Samples Using Liquid–Liquid Extraction

2015 ◽  
pp. bmv157 ◽  
Author(s):  
Bilal Yilmaz ◽  
Sakir Arslan
Keyword(s):  
Human Plasma ◽  
Liquid Extraction ◽  
Fluorometric Detection ◽  
Plasma Samples ◽  
Liquid Liquid Extraction ◽  
Human Plasma Samples

scholarly journals Development of an UPLC-MS/MS Method for Quantitative Analysis of Clotrimazole in Human Plasma Samples

Separations ◽  
2020 ◽  
Vol 7 (4) ◽  
pp. 62
Author(s):  
Lucia Lisi ◽  
Gabriella Maria Pia Ciotti ◽  
Pierluigi Navarra
Keyword(s):  
Human Plasma ◽  
Plasma Concentrations ◽  
Correlation Coefficients ◽  
Ultra Performance Liquid Chromatography ◽  
Plasma Samples ◽  
Nominal Concentration ◽  
Liquid Liquid Extraction ◽  
Human Plasma Samples ◽  
Liquid Chromatography Tandem Mass ◽  
Intravaginal Administration

An ultra-performance liquid chromatography-tandem mass spectrometry method was developed for the quantification of clotrimazole (CTZ) plasma levels after intravaginal administration of the drug given at approved dosages. Plasma samples were extracted by liquid–liquid extraction and a single chromatographic run could be completed within about 2 min. The method was linear over the investigated range (0.488–250 ng/mL) with all the correlation coefficients, R2, greater than 0.9903. All data were in the range of ±15.0% with respect to the nominal concentration for high QC and medium QC, and in the range ±20% with respect to the nominal concentration for low QC. This rapid and sensitive method was validated and could be applied to human plasma samples from a healthy volunteer, showing that the assay is able to detect plasma concentrations of CTZ in the range of those found after the administration of the drug at approved dosages in the clinical setting.

scholarly journals Protocol to analyze circulating small non-coding RNAs by high-throughput RNA sequencing from human plasma samples

2021 ◽  
Vol 2 (3) ◽  
pp. 100606
Author(s):  
Giuseppina E. Grieco ◽  
Guido Sebastiani ◽  
Daniela Fignani ◽  
Noemi Brusco ◽  
Laura Nigi ◽  
...  
Keyword(s):  
Human Plasma ◽  
Rna Sequencing ◽  
High Throughput ◽  
Plasma Samples ◽  
Human Plasma Samples ◽  
Non Coding Rnas

Optimizationvia experimental design of an SPE-HPLC-UV-fluorescence method for the determination of valsartan and its metabolite in human plasma samples

2006 ◽  
Vol 29 (15) ◽  
pp. 2265-2283 ◽  
Author(s):  
Gorka Iriarte ◽  
Nerea Ferreirós ◽  
Izaskun Ibarrondo ◽  
Rosa Maria Alonso ◽  
Miren Itxaso Maguregi ◽  
...  
Keyword(s):  
Experimental Design ◽  
Human Plasma ◽  
Fluorescence Method ◽  
Plasma Samples ◽  
Uv Fluorescence ◽  
Human Plasma Samples

An HPLC Determination of Trimetazidine in Human Plasma Using Liquid‐Liquid Extraction for Sample Clean‐Up

2005 ◽  
Vol 28 (9) ◽  
pp. 1299-1309 ◽  
Author(s):  
Min Kyo Jeoung ◽  
Kyoung Soon Kim ◽  
Chang Soo Kim ◽  
Nam Hee Kim ◽  
Youn‐Bok Chung ◽  
...  
Keyword(s):  
Human Plasma ◽  
Liquid Extraction ◽  
Hplc Determination ◽  
Liquid Liquid Extraction

scholarly journals Comparison of 4-plex to 8-plex iTRAQ Quantitative Measurements of Proteins in Human Plasma Samples

2012 ◽  
Vol 11 (7) ◽  
pp. 3774-3781 ◽  
Author(s):  
Gwenael Pottiez ◽  
Jayme Wiederin ◽  
Howard S. Fox ◽  
Pawel Ciborowski
Keyword(s):  
Human Plasma ◽  
Plasma Samples ◽  
Quantitative Measurements ◽  
Human Plasma Samples
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