scholarly journals An fMRI Study of Functional Abnormalities in the Verbal Working Memory System and the Relationship to Clinical Symptoms in Chronic Schizophrenia

2009 ◽  
Vol 20 (1) ◽  
pp. 46-60 ◽  
Author(s):  
Ryu-ichiro Hashimoto ◽  
KangUk Lee ◽  
Alexander Preus ◽  
Robert W. McCarley ◽  
Cynthia G. Wible
Keyword(s):  
Working Memory ◽  
Clinical Symptoms ◽  
Verbal Working Memory ◽  
Chronic Schizophrenia ◽  
Memory System ◽  
Fmri Study ◽  
The Relationship

scholarly journals The Relationship between Executive Functions and Language Production in 5–6-Year-Old Children: Insights from Working Memory and Storytelling

2020 ◽  
Vol 10 (2) ◽  
pp. 52
Author(s):  
Aleksander Veraksa ◽  
Daria Bukhalenkova ◽  
Natalia Kartushina ◽  
Ekaterina Oshchepkova
Keyword(s):  
Working Memory ◽  
Language Production ◽  
Working Memory Capacity ◽  
Narrative Structure ◽  
Verbal Working Memory ◽  
Memory Capacity ◽  
Story Retelling ◽  
Grammatical Accuracy ◽  
The Relationship ◽  
Global Indicators

This study examined the relationship between working memory capacity and narrative abilities in 5–6-year-old children. 269 children were assessed on their visual and verbal working memory and performed in a story retelling and a story creation (based on a single picture and on a series of pictures) tasks. The stories were evaluated on their macrostructure and microstructure. The results revealed a significant relationship between both components (verbal and visual) of working memory and the global indicators of a story’s macrostructure—such as semantic completeness, semantic adequacy, programming and narrative structure—and with the indicators of a story’s microstructure, such as grammatical accuracy and number of syntagmas. Yet, this relationship was systematically stronger for verbal working memory, as compared to visual working memory, suggesting that a well-developed verbal working memory leads to lexically and grammatically more accurate language production in preschool children.

Increased frontocerebellar activation in alcoholics during verbal working memory: an fMRI study

NeuroImage ◽  
2003 ◽  
Vol 19 (4) ◽  
pp. 1510-1520 ◽  
Author(s):  
John E Desmond ◽  
S.H.Annabel Chen ◽  
Eve DeRosa ◽  
Michelle R Pryor ◽  
Adolf Pfefferbaum ◽  
...  
Keyword(s):  
Working Memory ◽  
Verbal Working Memory ◽  
Fmri Study

Decreased processing speed might account for working memory span deficit in schizophrenia, and might mediate the associations between working memory span and clinical symptoms

2014 ◽  
Vol 29 (8) ◽  
pp. 473-478 ◽  
Author(s):  
G. Brébion ◽  
C. Stephan-Otto ◽  
E. Huerta-Ramos ◽  
J. Usall ◽  
M. Perez del Olmo ◽  
...  
Keyword(s):  
Working Memory ◽  
Processing Speed ◽  
Memory Impairment ◽  
Negative Symptoms ◽  
Memory Span ◽  
Clinical Symptoms ◽  
Verbal Working Memory ◽  
Motor Speed ◽  
Speed Measure ◽  
Cognitive Speed

AbstractObjectiveVerbal working memory span is decreased in patients with schizophrenia, and this might contribute to impairment in higher cognitive functions as well as to the formation of certain clinical symptoms. Processing speed has been identified as a crucial factor in cognitive efficiency in this population. We tested the hypothesis that decreased processing speed underlies the verbal working memory deficit in patients and mediates the associations between working memory span and clinical symptoms.MethodForty-nine schizophrenia inpatients recruited from units for chronic and acute patients, and forty-five healthy participants, were involved in the study. Verbal working memory span was assessed by means of the letter-number span. The Digit Copy test was used to assess motor speed, and the Digit Symbol Substitution Test to assess cognitive speed.ResultsThe working memory span was significantly impaired in patients (F(1,90) = 4.6, P < 0.05). However, the group difference was eliminated when either the motor or the cognitive speed measure was controlled (F(1,89) = 0.03, P = 0.86, and F(1,89) = 0.03, P = 0.88). In the patient group, working memory span was significantly correlated with negative symptoms (r = –0.52, P < 0.0001) and thought disorganisation (r = –0.34, P < 0.025) scores. Regression analyses showed that the association with negative symptoms was no longer significant when the motor speed measure was controlled (β = –0.12, P = 0.20), while the association with thought disorganisation was no longer significant when the cognitive speed measure was controlled (β = –0.10, P = 0.26).ConclusionsDecrement in motor and cognitive speed plays a significant role in both the verbal working memory impairment observed in patients and the associations between verbal working memory impairment and clinical symptoms.

The Relationship Between Age, Verbal Working Memory, and Language Comprehension.

2004 ◽  
Vol 19 (4) ◽  
pp. 601-616 ◽  
Author(s):  
Gayle DeDe ◽  
David Caplan ◽  
Karen Kemtes ◽  
Gloria Waters
Keyword(s):  
Working Memory ◽  
Language Comprehension ◽  
Verbal Working Memory ◽  
The Relationship

Processing efficiency of a verbal working memory system is modulated by amphetamine: an fMRI investigation

2005 ◽  
Vol 180 (4) ◽  
pp. 634-643 ◽  
Author(s):  
Christine M. Tipper ◽  
Tara A. Cairo ◽  
Todd S. Woodward ◽  
Anthony G. Phillips ◽  
Peter F. Liddle ◽  
...  
Keyword(s):  
Working Memory ◽  
Verbal Working Memory ◽  
Memory System ◽  
Processing Efficiency

scholarly journals Acute Ketamine Administration Alters the Brain Responses to Executive Demands in a Verbal Working Memory Task: an fMRI Study

2004 ◽  
Vol 29 (6) ◽  
pp. 1203-1214 ◽  
Author(s):  
R A E Honey ◽  
G D Honey ◽  
C O'Loughlin ◽  
S R Sharar ◽  
D Kumaran ◽  
...  
Keyword(s):  
Working Memory ◽  
Memory Task ◽  
Verbal Working Memory ◽  
Brain Responses ◽  
Fmri Study ◽  
The Brain
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