scholarly journals The Different Neural Correlates of Action and Functional Knowledge in Semantic Memory: An fMRI Study

2007 ◽  
Vol 18 (4) ◽  
pp. 740-751 ◽  
Author(s):  
N. Canessa ◽  
F. Borgo ◽  
S. F. Cappa ◽  
D. Perani ◽  
A. Falini ◽  
...  
Keyword(s):  
Semantic Memory ◽  
Neural Correlates ◽  
Fmri Study ◽  
Functional Knowledge

Reduced functional connectivity in brain networks underlying paired associates memory encoding in schizophrenia

2021 ◽  
Author(s):  
Meighen Roes ◽  
Abhijit Mahesh Chinchani ◽  
Todd Woodward
Keyword(s):  
Semantic Memory ◽  
Biological Marker ◽  
Principal Component ◽  
Neural Correlates ◽  
Healthy Controls ◽  
Linguistic Processing ◽  
Paired Associates ◽  
Fmri Study ◽  
Reduced Activity ◽  
Language Network

Patients with schizophrenia exhibit deficits in associative learning and semantic memory. The current functional magnetic resonance imaging (fMRI) study investigated the neural correlates of successful versus unsuccessful semantic associative encoding in schizophrenia compared to healthy controls. Publicly shared fMRI data from the UCLA Consortium for Neuropsychiatric Phenomics LA5C study were analyzed. Forty-four patients with schizophrenia and 78 healthy controls performed a paired-associates encoding task. Constrained principal component analysis for fMRI (fMRI-CPCA) revealed three distinct functional networks recruited during encoding: a responding (RESP) network, a linguistic processing/attention network (LANG/ATTN), and the default mode network (DMN). Relative to healthy controls, patients showed aberrant activity in all three networks; namely, hypo-activation in the LANG/ATTN network during successful encoding, lower peak activation and weaker post-activation suppression of the RESP network, and weaker suppression in the DMN during successful encoding. Independent of group effects, a pattern of stronger anticorrelating LANG/ATTN-DMN activity during successful encoding significantly predicted subsequent retrieval of paired associates. Together with previous observations of language network hypoactivation during controlled semantic associative memory processes, these results suggest that reduced activity in linguistic processing areas is a reliable biological marker associated with impaired semantic memory in schizophrenia.

Neural correlates of episodic and semantic memory retrieval in borderline personality disorder: An fMRI study

2009 ◽  
Vol 171 (2) ◽  
pp. 94-105 ◽  
Author(s):  
Christoph Mensebach ◽  
Thomas Beblo ◽  
Martin Driessen ◽  
Katja Wingenfeld ◽  
Markus Mertens ◽  
...  
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Semantic Memory ◽  
Memory Retrieval ◽  
Neural Correlates ◽  
Borderline Personality ◽  
Fmri Study

The neural correlates of romantic love following rejection: An fMRI study

2006 ◽  
Author(s):  
Arthur Aron ◽  
Helen Fisher ◽  
Greg Strong ◽  
Deb Mashek ◽  
HaiFang Li ◽  
...  
Keyword(s):  
Romantic Love ◽  
Neural Correlates ◽  
Fmri Study

Neural correlates of conflict resolution in an object-based Simon effect: An fMRI study

2013 ◽  
Author(s):  
Antonello Pellicano ◽  
Houpand Horoufchin ◽  
Harshal Patel ◽  
Iring Koch ◽  
Ferdinand Binkofski
Keyword(s):  
Conflict Resolution ◽  
Simon Effect ◽  
Neural Correlates ◽  
Object Based ◽  
Fmri Study

Neural correlates of intuition: an event-related fMRI study of implicit perception of semantic coherence

2004 ◽  
Vol 31 (S 1) ◽  
Author(s):  
R Ilg ◽  
K Vogeley ◽  
T Goschke ◽  
A Bolte ◽  
NJ Shah ◽  
...  
Keyword(s):  
Neural Correlates ◽  
Semantic Coherence ◽  
Fmri Study ◽  
Implicit Perception

Neural Correlates in Patients with Major Affective Disorders: An fMRI Study

2018 ◽  
Vol 16 (8) ◽  
Author(s):  
Gianluca Serafini ◽  
Maurizio Pompili ◽  
Andrea Romano ◽  
Denise Erbuto ◽  
Dorian A. Lamis ◽  
...  
Keyword(s):  
Affective Disorders ◽  
Neural Correlates ◽  
Fmri Study

scholarly journals Effects of ketamine on brain function during metacognition of episodic memory

2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Mirko Lehmann ◽  
Claudia Neumann ◽  
Sven Wasserthal ◽  
Johannes Schultz ◽  
Achilles Delis ◽  
...  
Keyword(s):  
Episodic Memory ◽  
Parietal Lobe ◽  
Memory Task ◽  
Reaction Times ◽  
Neural Correlates ◽  
Double Blind ◽  
Lingual Gyrus ◽  
States Of Consciousness ◽  
Fmri Study ◽  
Confidence Ratings

Abstract Only little research has been conducted on the pharmacological underpinnings of metacognition. Here, we tested the modulatory effects of a single intravenous dose (100 ng/ml) of the N-methyl-D-aspartate-glutamate-receptor antagonist ketamine, a compound known to induce altered states of consciousness, on metacognition and its neural correlates. Fifty-three young, healthy adults completed two study phases of an episodic memory task involving both encoding and retrieval in a double-blind, placebo-controlled fMRI study. Trial-by-trial confidence ratings were collected during retrieval. Effects on the subjective state of consciousness were assessed using the 5D-ASC questionnaire. Confirming that the drug elicited a psychedelic state, there were effects of ketamine on all 5D-ASC scales. Acute ketamine administration during retrieval had deleterious effects on metacognitive sensitivity (meta-d′) and led to larger metacognitive bias, with retrieval performance (d′) and reaction times remaining unaffected. However, there was no ketamine effect on metacognitive efficiency (meta-d′/d′). Measures of the BOLD signal revealed that ketamine compared to placebo elicited higher activation of posterior cortical brain areas, including superior and inferior parietal lobe, calcarine gyrus, and lingual gyrus, albeit not specific to metacognitive confidence ratings. Ketamine administered during encoding did not significantly affect performance or brain activation. Overall, our findings suggest that ketamine impacts metacognition, leading to significantly larger metacognitive bias and deterioration of metacognitive sensitivity as well as unspecific activation increases in posterior hot zone areas of the neural correlates of consciousness.

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