scholarly journals Heterogenous effect of androgen receptor CAG tract length on testicular germ cell tumor risk: shorter repeats associated with seminoma but not other histologic types

2011 ◽  
Vol 32 (8) ◽  
pp. 1238-1243 ◽  
Author(s):  
Carol A. Davis-Dao ◽  
Kimberly D. Siegmund ◽  
David J. Vandenberg ◽  
Eila C. Skinner ◽  
Gerhard A. Coetzee ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Germ Cell ◽  
Germ Cell Tumor ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Testicular Germ Cell ◽  
Tract Length ◽  
Tumor Risk ◽  
Histologic Types

Abstract 811: Mosaic chromosome Y loss is not associated with testicular germ cell tumor risk

2016 ◽  
Author(s):  
Mitchell J. Machiela ◽  
Casey L. Dagnall ◽  
Anand Pathak ◽  
Jennifer T. Loud ◽  
Stephen J. Chanock ◽  
...  
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Testicular Germ Cell ◽  
Chromosome Y ◽  
Tumor Risk

scholarly journals Meta-Analysis of Gene Expressions in Testicular Germ Cell Tumor Histologies

2020 ◽  
Vol 21 (12) ◽  
pp. 4487
Author(s):  
Finn Edler von Eyben ◽  
Jorge Parraga-Alava
Keyword(s):  
Germ Cell ◽  
Candidate Genes ◽  
Germ Cell Tumor ◽  
Meta Analysis ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Rna Expression ◽  
Tumor Type ◽  
Testicular Germ Cell ◽  
Histologic Types

There is no consensus as to how a precursor lesion, germ cell neoplasia in situ (GCNIS), develops into the histologic types of testicular germ cell tumor type II (TGCT). The present meta-analysis examined RNA expressions of 24 candidate genes in three datasets. They included 203 samples of normal testis (NT) and histologic types of TGCT. The Fisher’s test for combined p values was used for meta-analysis of the RNA expressions in the three datasets. The histologic types differed in RNA expression of PRAME, KIT, SOX17, NANOG, KLF4, POU5F1, RB1, DNMT3B, and LIN28A (p < 0.01). The histologic types had concordant differences in RNA expression of the genes in the three datasets. Eight genes had overlap with a high RNA expression in at least two histologic types. In contrast, only seminoma (SE) had a high RNA expression of KLF4 and only embryonal carcinoma (EC) had a high RNA expression of DNMT3B. In conclusion, the meta-analysis showed that the development of the histologic types of TGCT was driven by changes in RNA expression of candidate genes. According to the RNA expressions of the ten genes, TGCT develops from NT over GCNIS, SE, EC, to the differentiated types of TGCT.

scholarly journals Genetically inferred telomere length and testicular germ cell tumor risk

2021 ◽  
pp. cebp.1775.2020
Author(s):  
Derek W Brown ◽  
Qing Lan ◽  
Nathaniel Rothman ◽  
John Pluta ◽  
Kristian Almstrup ◽  
...  
Keyword(s):  
Germ Cell ◽  
Telomere Length ◽  
Germ Cell Tumor ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Testicular Germ Cell ◽  
Tumor Risk

scholarly journals Mosaic chromosome Y loss and testicular germ cell tumor risk

2017 ◽  
Vol 62 (6) ◽  
pp. 637-640 ◽  
Author(s):  
Mitchell J Machiela ◽  
Casey L Dagnall ◽  
Anand Pathak ◽  
Jennifer T Loud ◽  
Stephen J Chanock ◽  
...  
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Testicular Germ Cell ◽  
Chromosome Y ◽  
Tumor Risk

Insulin-like Growth Factor 1, Insulin-like Growth Factor-Binding Protein 3, and Testicular Germ-Cell Tumor Risk

2008 ◽  
Vol 167 (12) ◽  
pp. 1438-1445 ◽  
Author(s):  
V. M. Chia ◽  
S. M. Quraishi ◽  
B. I. Graubard ◽  
M. V. Rubertone ◽  
R. L. Erickson ◽  
...  
Keyword(s):  
Growth Factor ◽  
Germ Cell ◽  
Germ Cell Tumor ◽  
Binding Protein ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Insulin Like Growth Factor ◽  
Testicular Germ Cell ◽  
Factor Binding ◽  
Tumor Risk

Testicular germ cell tumor with pineal metastases

Neurosurgery ◽  
1990 ◽  
pp. 688 ◽  
Author(s):  
B Delahunt ◽  
H H Teoh ◽  
V Balakrishnan ◽  
J N Nacey ◽  
S P Clark
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Testicular Germ Cell

666 A NOVEL RISK STRATIFICATION SYSTEM FOR CHEMOTHERAPY FAILURE IN TESTICULAR GERM CELL TUMOR

2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Jessica Lubahn ◽  
Nicholas Cost ◽  
Mehrad Adibi ◽  
Adam Romman ◽  
Ganesh Raj ◽  
...  
Keyword(s):  
Risk Stratification ◽  
Germ Cell ◽  
Germ Cell Tumor ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Testicular Germ Cell ◽  
Stratification System ◽  
Risk Stratification System

scholarly journals A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility

2011 ◽  
Vol 20 (15) ◽  
pp. 3109-3117 ◽  
Author(s):  
Peter A. Kanetsky ◽  
Nandita Mitra ◽  
Saran Vardhanabhuti ◽  
David J. Vaughn ◽  
Mingyao Li ◽  
...  
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Testicular Germ Cell ◽  
Tumor Susceptibility ◽  
Independent Locus
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