scholarly journals Imbalance in habitual versus goal directed neural systems during symptom provocation in obsessive-compulsive disorder

Brain ◽  
2015 ◽  
Vol 138 (3) ◽  
pp. 798-811 ◽  
Author(s):  
Paula Banca ◽  
Valerie Voon ◽  
Martin D. Vestergaard ◽  
Gregor Philipiak ◽  
Inês Almeida ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Neural Systems ◽  
Obsessive Compulsive ◽  
Symptom Provocation ◽  
Compulsive Disorder

scholarly journals Hyperactivation of the Frontal Control Network Revealed by Symptom Provocation in Obsessive-Compulsive Disorder Using EEG Microstate and sLORETA Analyses

2018 ◽  
Vol 77 (4) ◽  
pp. 176-185 ◽  
Author(s):  
Masafumi Yoshimura ◽  
Roberto D. Pascual-Marqui ◽  
Keiichiro Nishida ◽  
Yuichi Kitaura ◽  
Hiroshi Mii ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Control Network ◽  
Obsessive Compulsive ◽  
Symptom Provocation ◽  
Compulsive Disorder

scholarly journals Neural correlates of symptom provocation in pediatric obsessive-compulsive disorder

2019 ◽  
Vol 24 ◽  
pp. 102034 ◽  
Author(s):  
Fern Jaspers-Fayer ◽  
Sarah Yao Lin ◽  
Elaine Chan ◽  
Rhonda Ellwyn ◽  
Ryan Lim ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Neural Correlates ◽  
Obsessive Compulsive ◽  
Symptom Provocation ◽  
Compulsive Disorder

Patterns of Neural Response to Emotive Stimuli Distinguish the Different Symptom Dimensions of Obsessive-Compulsive Disorder

CNS Spectrums ◽  
2004 ◽  
Vol 9 (4) ◽  
pp. 275-283 ◽  
Author(s):  
Mary L. Phillips ◽  
David Mataix-Cols
Keyword(s):  
Treatment Response ◽  
Obsessive Compulsive Disorder ◽  
Emotion Perception ◽  
Anterior Cingulate ◽  
Neural Systems ◽  
Obsessive Compulsive ◽  
Specific Symptom ◽  
Symptom Dimensions ◽  
Related Material ◽  
Compulsive Disorder

ABSTRACTDespite its heterogeneous symptomatology, obsessive-compulsive disorder (OCD) is currently conceptualized as a unitary diagnostic entity. Recent factor-analytic studies have identified several OCD symptom dimensions that are associated with different demographic variables, comorbidity, patterns of genetic transmission, and treatment response. Functional abnormalities in neural systems important for emotion perception, including the orbitofrontal cortex, lateral prefrontal cortex, anterior cingulate gyrus, and limbic regions, have been reported in OCD. In this review, we discuss the extent to which neurobiological markers may distinguish these different symptom dimensions and whether specific symptom dimensions, such as contamination/washing, are associated with abnormalities in emotion and, in particular, disgust, perception in OCD. Also discussed are findings that indicate that anxiety can be induced in healthy volunteers in response to OCD symptom-related material, and that associated increases in activity within neural systems important for emotion perception occur to washing- and hoarding-related material in particular in these subjects. Further examination of neural responses during provocation of different symptom dimensions in OCD patients will help determine the extent to which specific abnormalities in neural systems underlying emotion perception are associated with different symptom dimensions and predict treatment response in OCD.

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