Human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery

Daniel Tornero; Somsak Wattananit; Marita Grønning Madsen; Philipp Koch; James Wood; Jemal Tatarishvili; Yutaka Mine; Ruimin Ge; Emanuela Monni; Karthikeyan Devaraju; Robert F. Hevner; Oliver Brüstle; Olle Lindvall; Zaal Kokaia

doi:10.1093/brain/awt278

Human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery

Brain ◽

10.1093/brain/awt278 ◽

2013 ◽

Vol 136 (12) ◽

pp. 3561-3577 ◽

Cited By ~ 151

Author(s):

Daniel Tornero ◽

Somsak Wattananit ◽

Marita Grønning Madsen ◽

Philipp Koch ◽

James Wood ◽

...

Keyword(s):

Stem Cell ◽

Functional Recovery ◽

Cortical Neurons ◽

Pluripotent Stem Cell ◽

Induced Pluripotent Stem Cell ◽

Induced Pluripotent

Download Full-text

The GluN2B subunit represents a major functional determinant of NMDA receptors in human induced pluripotent stem cell-derived cortical neurons

Stem Cell Research ◽

10.1016/j.scr.2018.02.002 ◽

2018 ◽

Vol 28 ◽

pp. 105-114 ◽

Cited By ~ 2

Author(s):

Ioana Neagoe ◽

Chang Liu ◽

Alexander Stumpf ◽

Yanmei Lu ◽

Dongping He ◽

...

Keyword(s):

Stem Cell ◽

Nmda Receptors ◽

Cortical Neurons ◽

Pluripotent Stem Cell ◽

Induced Pluripotent Stem Cell ◽

Functional Determinant ◽

Induced Pluripotent

Download Full-text

Functional recovery of the murine brain ischemia model using human induced pluripotent stem cell-derived telencephalic progenitors

Brain Research ◽

10.1016/j.brainres.2012.03.049 ◽

2012 ◽

Vol 1459 ◽

pp. 52-60 ◽

Cited By ~ 31

Author(s):

Masanori Gomi ◽

Yasushi Takagi ◽

Asuka Morizane ◽

Daisuke Doi ◽

Masaki Nishimura ◽

...

Keyword(s):

Stem Cell ◽

Brain Ischemia ◽

Functional Recovery ◽

Pluripotent Stem Cell ◽

Induced Pluripotent Stem Cell ◽

Murine Brain ◽

Induced Pluripotent

Download Full-text

Pathological manifestation of the induced pluripotent stem cell‐derived cortical neurons from an early‐onset Alzheimer's disease patient carrying a presenilin‐1 mutation (S170F)

Cell Proliferation ◽

10.1111/cpr.12798 ◽

2020 ◽

Vol 53 (4) ◽

Cited By ~ 2

Author(s):

Ling Li ◽

Hee Jin Kim ◽

Jee Hoon Roh ◽

Minchul Kim ◽

Wonyoung Koh ◽

...

Keyword(s):

Stem Cell ◽

Cortical Neurons ◽

Pluripotent Stem Cell ◽

Disease Patient ◽

Induced Pluripotent Stem Cell ◽

Presenilin 1 ◽

Presenilin 1 Mutation ◽

Early Onset Alzheimer’S Disease ◽

Induced Pluripotent ◽

Pathological Manifestation

Download Full-text

Comparison of Human Induced Pluripotent Stem Cell-Derived Neurons and Rat Primary Cortical Neurons as In Vitro Models of Neurite Outgrowth

Applied In Vitro Toxicology ◽

10.1089/aivt.2015.0025 ◽

2016 ◽

Vol 2 (1) ◽

pp. 26-36 ◽

Cited By ~ 3

Author(s):

Ingrid Druwe ◽

Theresa M. Freudenrich ◽

Kathleen Wallace ◽

Timothy J. Shafer ◽

William R. Mundy

Keyword(s):

Stem Cell ◽

Neurite Outgrowth ◽

Cortical Neurons ◽

Pluripotent Stem Cell ◽

Induced Pluripotent Stem Cell ◽

In Vitro Models ◽

Primary Cortical Neurons ◽

Induced Pluripotent

Download Full-text

Induction of long-term potentiation and depression phenomena in human induced pluripotent stem cell-derived cortical neurons

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2015.12.087 ◽

2016 ◽

Vol 469 (4) ◽

pp. 856-862 ◽

Cited By ~ 12

Author(s):

A. Odawara ◽

H. Katoh ◽

N. Matsuda ◽

I. Suzuki

Keyword(s):

Stem Cell ◽

Cortical Neurons ◽

Pluripotent Stem Cell ◽

Induced Pluripotent Stem Cell ◽

Long Term Potentiation ◽

Term Potentiation ◽

Induced Pluripotent

Download Full-text

Long-term potentiation and depression phenomena in human induced pluripotent stem cell-derived cortical neurons

Frontiers in Neuroscience ◽

10.3389/conf.fnins.2016.93.00065 ◽

2016 ◽

Vol 10 ◽

Author(s):

Odawara Aoi ◽

Katoh Hiroki ◽

Matsuda Naoki ◽

Suzuki Ikuro

Keyword(s):

Stem Cell ◽

Cortical Neurons ◽

Pluripotent Stem Cell ◽

Induced Pluripotent Stem Cell ◽

Long Term Potentiation ◽

Term Potentiation ◽

Induced Pluripotent

Download Full-text

Synchronous firing patterns of induced pluripotent stem cell-derived cortical neurons depend on the network structure consisting of excitatory and inhibitory neurons

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2018.04.197 ◽

2018 ◽

Vol 501 (1) ◽

pp. 152-157 ◽

Cited By ~ 7

Author(s):

Shoko Iida ◽

Kenta Shimba ◽

Koji Sakai ◽

Kiyoshi Kotani ◽

Yasuhiko Jimbo

Keyword(s):

Stem Cell ◽

Network Structure ◽

Cortical Neurons ◽

Pluripotent Stem Cell ◽

Induced Pluripotent Stem Cell ◽

Inhibitory Neurons ◽

Firing Patterns ◽

Synchronous Firing ◽

Induced Pluripotent

Download Full-text

Rewiring the ischaemic brain with human-induced pluripotent stem cell-derived cortical neurons

Brain ◽

10.1093/brain/awt330 ◽

2013 ◽

Vol 136 (12) ◽

pp. 3525-3527 ◽

Cited By ~ 8

Author(s):

Stefano Pluchino ◽

Luca Peruzzotti-Jametti

Keyword(s):

Stem Cell ◽

Cortical Neurons ◽

Pluripotent Stem Cell ◽

Induced Pluripotent Stem Cell ◽

Ischaemic Brain ◽

Induced Pluripotent

Download Full-text

Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1108077108 ◽

2011 ◽

Vol 108 (40) ◽

pp. 16825-16830 ◽

Cited By ~ 325

Author(s):

S. Nori ◽

Y. Okada ◽

A. Yasuda ◽

O. Tsuji ◽

Y. Takahashi ◽

...

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Stem Cell ◽

Functional Recovery ◽

Pluripotent Stem Cell ◽

Induced Pluripotent Stem Cell ◽

Cord Injury ◽

Induced Pluripotent

Download Full-text

Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics

Human Molecular Genetics ◽

10.1093/hmg/ddv637 ◽

2016 ◽

Vol 25 (5) ◽

pp. 989-1000 ◽

Cited By ~ 52

Author(s):

Adam E. Handel ◽

Satyan Chintawar ◽

Tatjana Lalic ◽

Emma Whiteley ◽

Jane Vowles ◽

...

Keyword(s):

Stem Cell ◽

Single Cell ◽

Cortical Neurons ◽

Pluripotent Stem Cell ◽

Induced Pluripotent Stem Cell ◽

Cortical Layer ◽

Induced Pluripotent ◽

Primary Tissue

Download Full-text