scholarly journals Impairments of auditory scene analysis in Alzheimer's disease

Brain ◽  
2011 ◽  
Vol 135 (1) ◽  
pp. 190-200 ◽  
Author(s):  
J. C. Goll ◽  
L. G. Kim ◽  
G. R. Ridgway ◽  
J. C. Hailstone ◽  
M. Lehmann ◽  
...  
2015 ◽  
Vol 7 ◽  
pp. 699-708 ◽  
Author(s):  
Hannah L. Golden ◽  
Jennifer L. Agustus ◽  
Johanna C. Goll ◽  
Laura E. Downey ◽  
Catherine J. Mummery ◽  
...  

Brain ◽  
2020 ◽  
Vol 143 (9) ◽  
pp. 2689-2695 ◽  
Author(s):  
Chris J D Hardy ◽  
Keir X X Yong ◽  
Johanna C Goll ◽  
Sebastian J Crutch ◽  
Jason D Warren

Abstract Although posterior cortical atrophy is often regarded as the canonical ‘visual dementia’, auditory symptoms may also be salient in this disorder. Patients often report particular difficulty hearing in busy environments; however, the core cognitive process—parsing of the auditory environment (‘auditory scene analysis’)—has been poorly characterized. In this cross-sectional study, we used customized perceptual tasks to assess two generic cognitive operations underpinning auditory scene analysis—sound source segregation and sound event grouping—in a cohort of 21 patients with posterior cortical atrophy, referenced to 15 healthy age-matched individuals and 21 patients with typical Alzheimer’s disease. After adjusting for peripheral hearing function and performance on control tasks assessing perceptual and executive response demands, patients with posterior cortical atrophy performed significantly worse on both auditory scene analysis tasks relative to healthy controls and patients with typical Alzheimer’s disease (all P < 0.05). Our findings provide further evidence of central auditory dysfunction in posterior cortical atrophy, with implications for our pathophysiological understanding of Alzheimer syndromes as well as clinical diagnosis and management.


2014 ◽  
Vol 78 (3) ◽  
pp. 361-378 ◽  
Author(s):  
Mona Isabel Spielmann ◽  
Erich Schröger ◽  
Sonja A. Kotz ◽  
Alexandra Bendixen

Author(s):  
Meghan Goodchild ◽  
Stephen McAdams

The study of timbre and orchestration in music research is underdeveloped, with few theories to explain instrumental combinations and orchestral shaping. This chapter will outline connections between the orchestration practices of the nineteenth and early twentieth centuries and perceptual principles based on recent research in auditory scene analysis and timbre perception. Analyses of orchestration treatises and musical scores reveal an implicit understanding of auditory grouping principles by which many orchestral effects and techniques function. We will explore how concurrent grouping cues result in blended combinations of instruments, how sequential grouping into segregated melodies or stratified (foreground and background) layers is influenced by timbral similarities and dissimilarities, and how segmental grouping cues create formal boundaries and expressive gestural shaping through changes in instrumental textures. This exploration will be framed within an examination of historical and contemporary discussion of orchestral effects and techniques.


Sign in / Sign up

Export Citation Format

Share Document