scholarly journals Genetic and environmental influences on focal brain density in bipolar disorder

Brain ◽  
2010 ◽  
Vol 133 (10) ◽  
pp. 3080-3092 ◽  
Author(s):  
Astrid C. van der Schot ◽  
Ronald Vonk ◽  
Rachel M. Brouwer ◽  
G. Caroline M. van Baal ◽  
Rachel G. H. Brans ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Environmental Influences ◽  
Brain Density

scholarly journals The genetic and environmental influences of event-related gamma oscillations on bipolar disorder

2011 ◽  
Vol 13 (3) ◽  
pp. 260-271 ◽  
Author(s):  
Mei-Hua Hall ◽  
Kevin M Spencer ◽  
Katja Schulze ◽  
Colm McDonald ◽  
Sridevi Kalidindi ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Environmental Influences ◽  
Gamma Oscillations

scholarly journals Genetic and Environmental Influences on Pro-Inflammatory Monocytes in Bipolar Disorder

2009 ◽  
Vol 66 (9) ◽  
pp. 957 ◽  
Author(s):  
Roos C. Padmos ◽  
G. Caroline M. Van Baal ◽  
Ronald Vonk ◽  
Annemarie J. M. Wijkhuijs ◽  
René S. Kahn ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Environmental Influences ◽  
Inflammatory Monocytes

scholarly journals Genetic and environmental influences on circulating NK and T cells and their relation to bipolar disorder

2019 ◽  
Vol 7 (1) ◽  
Author(s):  
G. Snijders ◽  
R. Brouwer ◽  
S. Kemner ◽  
F. Bootsman ◽  
H. A. Drexhage ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
T Cells ◽  
Environmental Influences

scholarly journals Modeling complex genetic and environmental influences on comorbid bipolar disorder with tobacco use disorder

2010 ◽  
Vol 11 (1) ◽  
Author(s):  
Richard C McEachin ◽  
Nancy L Saccone ◽  
Scott F Saccone ◽  
Yelena D Kleyman-Smith ◽  
Tiara Kar ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Tobacco Use ◽  
Environmental Influences ◽  
Tobacco Use Disorder

Navigating Tx of Bipolar Disorder in Pregnancy

Ob Gyn News ◽  
2005 ◽  
Vol 40 (3) ◽  
pp. 11
Author(s):  
DIANA MAHONEY
Keyword(s):  
Bipolar Disorder ◽  
In Pregnancy

Valproate May Help Child With Bipolar Disorder

2005 ◽  
Vol 39 (5) ◽  
pp. 26
Author(s):  
Jeff Evans
Keyword(s):  
Bipolar Disorder

Bipolar Disorder

2017 ◽  
Author(s):  
Robert P. Reiser ◽  
Larry W. Thompson ◽  
Sheri L. Johnson ◽  
Trisha Suppes
Keyword(s):  
Bipolar Disorder

Behavioral Testing of Mice Concerning Anxiety and Depression

2015 ◽  
Vol 223 (3) ◽  
pp. 151-156 ◽  
Author(s):  
Nina Schweinfurth ◽  
Undine E. Lang
Keyword(s):  
Environmental Influences ◽  
Sickness Behavior ◽  
Laboratory Research ◽  
Anxiety And Depression ◽  
Housing Conditions ◽  
Human Beings ◽  
Behavioral Testing ◽  
New Developments ◽  
Animal Trials ◽  
Resilience Factors

Abstract. In the development of new psychiatric drugs and the exploration of their efficacy, behavioral testing in mice has always shown to be an inevitable procedure. By studying the behavior of mice, diverse pathophysiological processes leading to depression, anxiety, and sickness behavior have been revealed. Moreover, laboratory research in animals increased at least the knowledge about the involvement of a multitude of genes in anxiety and depression. However, multiple new possibilities to study human behavior have been developed recently and improved and enable a direct acquisition of human epigenetic, imaging, and neurotransmission data on psychiatric pathologies. In human beings, the high influence of environmental and resilience factors gained scientific importance during the last years as the search for key genes in the development of affective and anxiety disorders has not been successful. However, environmental influences in human beings themselves might be better understood and controllable than in mice, where environmental influences might be as complex and subtle. The increasing possibilities in clinical research and the knowledge about the complexity of environmental influences and interferences in animal trials, which had been underestimated yet, question more and more to what extent findings from laboratory animal research translate to human conditions. However, new developments in behavioral testing of mice involve the animals’ welfare and show that housing conditions of laboratory mice can be markedly improved without affecting the standardization of results.

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