scholarly journals Magnetic resonance imaging lesion pattern in Guadeloupean parkinsonism is distinct from progressive supranuclear palsy

Brain ◽  
2010 ◽  
Vol 133 (8) ◽  
pp. 2410-2425 ◽  
Author(s):  
S. Lehericy ◽  
A. Hartmann ◽  
A. Lannuzel ◽  
D. Galanaud ◽  
C. Delmaire ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Progressive Supranuclear Palsy ◽  
Resonance Imaging ◽  
Lesion Pattern ◽  
Magnetic Resonance Imaging Lesion

scholarly journals Post-Mortem 7.0-Tesla Magnetic Resonance Imaging of the Hippocampus in Progressive Supranuclear Palsy with and without Cerebral Amyloid Angiopathy

NeuroSci ◽  
2020 ◽  
Vol 1 (2) ◽  
pp. 115-120
Author(s):  
Jacques De Reuck ◽  
Florent Auger ◽  
Nicolas Durieux ◽  
Claude-Alain Maurage ◽  
Vincent Deramecourt ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Progressive Supranuclear Palsy ◽  
Cerebral Amyloid Angiopathy ◽  
Amyloid Angiopathy ◽  
Post Mortem ◽  
Resonance Imaging ◽  
Cerebral Amyloid ◽  
Magnetic Resonance Imaging Mri ◽  
Neuropathological Examination

Introduction and Purpose: Cerebral amyloid angiopathy (CAA) can be observed in patients with progressive supranuclear palsy (PSP), though to a lesser degree than in Alzheimer’s disease. The present post-mortem 7.0-tesla magnetic resonance imaging (MRI) evaluates whether CAA has an influence on the degree of hippocampal atrophy (HA) and on the incidence of associated micro-infarcts (HMIs) and cortical micro-bleeds (HMBs). Material and Methods: Eight brains with PSP-CAA were compared to 20 PSP brains without CAA. In addition to the neuropathological examination, the hippocampus was evaluated on the most representative coronal section with T2 and T2*-weighted MRI sequences. The average degree of HA was determined in both groups. The incidence of HMIs and HMBs was also compared as well as the frequency of cortical micro-infarcts (CoMIs) and cortical micro-bleeds (CoMBs) in the hemispheric neocortex. Results: The neuropathological examination showed a higher incidence of lacunar infarcts in the PSP-CAA brains compared to the PSP ones. With magnetic resonance imaging (MRI), the severity of HA and the incidence of HMIs and HMBs was similar between both groups. Additionally, the frequency of CoMIs and CoMBs in the neocortex was comparable. Conclusions: The association of CAA in PSP brains has no influence on the degree of HA and on the incidence of the small cerebrovascular lesions in the hippocampus as well as in the neocortex.

scholarly journals Lesion Pattern on Magnetic Resonance Imaging and Stroke Etiology in Multi-territorial Infarctions

2018 ◽  
Vol 24 (3) ◽  
pp. 94-97
Author(s):  
Ethem Murat Arsava ◽  
Lala Mehdikhanova ◽  
Rahşan Göçmen ◽  
Kader Karlı Oğuz ◽  
Mehmet Akif Topçuoğlu
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Stroke Etiology ◽  
Lesion Pattern

Magnetic Resonance Imaging Biomarkers Distinguish Normal Pressure Hydrocephalus From Progressive Supranuclear Palsy

2020 ◽  
Vol 35 (8) ◽  
pp. 1406-1415 ◽  
Author(s):  
Andrea Quattrone ◽  
Alessia Sarica ◽  
Domenico La Torre ◽  
Maurizio Morelli ◽  
Basilio Vescio ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Progressive Supranuclear Palsy ◽  
Normal Pressure Hydrocephalus ◽  
Normal Pressure ◽  
Imaging Biomarkers ◽  
Resonance Imaging

scholarly journals Alternating flexed-extended posturing in progressive supranuclear palsy

2019 ◽  
Vol 11 (3) ◽  
Author(s):  
Nobuyuki Ishii ◽  
Hitoshi Mochizuki
Keyword(s):  
Magnetic Resonance Imaging ◽  
Nursing Home ◽  
Magnetic Resonance ◽  
Progressive Supranuclear Palsy ◽  
Late Stage ◽  
Cerebral Atrophy ◽  
The Other ◽  
Resonance Imaging ◽  
History Of ◽  
The Brain

A 69-year-old man who had been bedridden in nursing home because of a 5-year history of progressive supranuclear palsy (PSP) was admitted due to aspiration pneumonia. Besides neck dystonia in extension, he showed “alternating flexed–extended posturing”, in which the arm was flexed on one side and extended on the other. Magnetic resonance imaging of the brain revealed global cerebral atrophy that predominantly affected the cortex and midbrain. The mechanisms of complex posturing in late-stage PSP may sometimes be related to decortication and decerebration as well as dystonia, and “alternating flexed–extended posturing” might be one of the phenotypes of pathological progression in PSP.

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