scholarly journals Microscopical observations on the cerebral circulation of the blood in the cerebral cortex, by Howard Florey (BA and John Lucas Walker Student; From the Physiological Laboratory, Oxford and Pathological Laboratory, Cambridge). Brain 1925: 48; 43-64

Brain ◽  
2010 ◽  
Vol 133 (4) ◽  
pp. 950-951
Author(s):  
A. Compston
Keyword(s):  
Cerebral Cortex ◽  
Cerebral Circulation ◽  
Physiological Laboratory ◽  
Circulation Of The Blood

scholarly journals VII. The exact histological localisation of the visual area of the human cerebral cortex

1900 ◽  
Vol 193 (185-193) ◽  
pp. 165-222 ◽  
Keyword(s):  
Cerebral Cortex ◽  
County Council ◽  
Visual Area ◽  
Human Cerebral Cortex ◽  
Human Cortex ◽  
Physiological Laboratory ◽  
Sensory Area ◽  
University College ◽  
Cortex Cerebri

The object of the present paper is to define by histological methods the exact limitations of the visuo-sensory area of the human cortex cerebri. The investigation to be described has occupied upwards of three years. It was commenced during the summer of 1896 in the pathological laboratory of the County Asylum, Rainhill, Lancashire; it was continued during the next three years in the physiological laboratory of Mason University College, Birmingham; and it has been completed in the pathological laboratory of the London County Council at Claybury. Owing to the remarkable facilities for research granted to workers in the last-named laboratory, it has been possible to bring this investigation to a much more rapid conclusion than would otherwise have been possible. A general summary of the paper follows this introduction, and it is succeeded for convenience of reference by a list of the sections into which the paper is divided.

scholarly journals XI. An investigation into the functions of the occipital and temporal lobes of the monkey's brain

1888 ◽  
Vol 179 ◽  
pp. 303-327 ◽  
Keyword(s):  
Cerebral Cortex ◽  
Exceptional Case ◽  
Neurological Society ◽  
Temporal Lobes ◽  
Physiological Laboratory ◽  
University College ◽  
The Subject ◽  
Preceding Winter

The experiments which we here record were performed during the preceding winter and spring in the physiological laboratory of University College, but their formal publication has been hitherto deferred because we were desirous of keeping some of the animals in which the lesions had been established under observation during several months, in order that any modification which that lapse of time might produce in the symptoms should be duly recorded. But, although not hitherto published, several of the cases, while still under such observation, have been brought before the notice of both the Physiological and the Neurological Society of London, and have been examined at different times by various persons interested in the subject of cerebral localisation, besides being familiar to the regular workers in the laboratory. In this way we have repeatedly had the opportunity of showing most of the symptoms which we are about to record, nor have we inserted any detail as to the accuracy of which there could, to an unbiased mind, be the slightest doubt. All our experiments have been performed with the view of establishing certain lesions, uni- or bi-lateral, embracing definite areas of the cerebral cortex; and they have been confined, or nearly so, to the occipital and temporal lobes. In the performance of the operations strict antiseptic precautions were employed, the dressings being fixed by a collodion cap. On the fourth or fifth day after the operation this cap and the dressings were removed, and in every case the wound was found to be completely closed, the edges of the skin being closely united, no sign of meningitis nor of any septic mischief being at any time perceptible. In one exceptional case, however, in which the antiseptic precautions had, from over confidence, been relaxed, the asepticism was incomplete, and sloughing of the skin over the seat of operation resulted, so that the animal had to be killed within a few days of the performance of the operation. This case will be mentioned in due course.

Author response for "Microchiropterans have a diminutive cerebral cortex, not an enlarged cerebellum, compared to megachiropterans and other mammals"

2020 ◽  
Author(s):  
Suzana Herculano‐Houzel ◽  
Felipe Barros Cunha ◽  
Jamie L. Reed ◽  
Consolate Kaswera‐Kyamakya ◽  
Emmanuel Gillissen ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Author Response

Oligodendrocytes in Developing Hameter Cerebral Cortex

1976 ◽  
Vol 34 ◽  
pp. 126-127
Author(s):  
MB. Tank Buschmann
Keyword(s):  
Cerebral Cortex ◽  
Optic Nerve ◽  
Frontal Cortex ◽  
Osmium Tetroxide ◽  
Sodium Cacodylate Buffer ◽  
Sodium Cacodylate ◽  
Tissue Samples ◽  
Cacodylate Buffer ◽  
Layer V ◽  
Adult Hamster

Development of oligodendrocytes in rat corpus callosum was described as a sequential change in cytoplasmic density which progressed from light to medium to dark (1). In rat optic nerve, changes in cytoplasmic density were not observed, but significant changes in morphology occurred just prior to and during myelination (2). In our study, the ultrastructural development of oligodendrocytes was studied in newborn, 5-, 10-, 15-, 20-day and adult frontal cortex of the golden hamster (Mesocricetus auratus).Young and adult hamster brains were perfused with paraformaldehyde-glutaraldehyde in sodium cacodylate buffer at pH 7.3 according to the method of Peters (3). Tissue samples of layer V of the frontal cortex were post-fixed in 2% osmium tetroxide, dehydrated in acetone and embedded in Epon-Araldite resin.

Glucuronyl 3-sulfate occurs exclusively on distal unmyelinated terminals of selected sensory neurons in the peripheral nervous system

1995 ◽  
Vol 53 ◽  
pp. 958-959
Author(s):  
S.S. Spicer ◽  
B.A. Schulte
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cerebral Cortex ◽  
Peripheral Nervous System ◽  
Sensory Neurons ◽  
Sensory Nerves ◽  
Tissue Antigens ◽  
The Central Nervous System ◽  
The Brain ◽  
Leu 7

Generation of monoclonal antibodies (MAbs) against tissue antigens has yielded several (VC1.1, HNK- 1, L2, 4F4 and anti-leu 7) which recognize the unique sugar epitope, glucuronyl 3-sulfate (Glc A3- SO4). In the central nervous system, these MAbs have demonstrated Glc A3-SO4 at the surface of neurons in the cerebral cortex, the cerebellum, the retina and other widespread regions of the brain.Here we describe the distribution of Glc A3-SO4 in the peripheral nervous system as determined by immunostaining with a MAb (VC 1.1) developed against antigen in the cat visual cortex. Outside the central nervous system, immunoreactivity was observed only in peripheral terminals of selected sensory nerves conducting transduction signals for touch, hearing, balance and taste. On the glassy membrane of the sinus hair in murine nasal skin, just deep to the ringwurt, VC 1.1 delineated an intensely stained, plaque-like area (Fig. 1). This previously unrecognized structure of the nasal vibrissae presumably serves as a tactile end organ and to our knowledge is not demonstrable by means other than its selective immunopositivity with VC1.1 and its appearance as a densely fibrillar area in H&E stained sections.

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