scholarly journals fMRI revealed neural substrate for reversible working memory dysfunction in subclinical hypothyroidism

Brain ◽  
2006 ◽  
Vol 129 (11) ◽  
pp. 2923-2930 ◽  
Author(s):  
D.-F. Zhu ◽  
Z.-X. Wang ◽  
D.-R. Zhang ◽  
Z.-L. Pan ◽  
S. He ◽  
...  
Keyword(s):  
Working Memory ◽  
Subclinical Hypothyroidism ◽  
Memory Dysfunction ◽  
Neural Substrate

ERP and behavioral indices of working memory dysfunction in schizophrenia

1996 ◽  
Vol 39 (7) ◽  
pp. 565 ◽  
Author(s):  
D.C. Javitt ◽  
A-M. Shelley ◽  
E. Leiderman ◽  
L. March ◽  
N. Cowan ◽  
...  
Keyword(s):  
Working Memory ◽  
Memory Dysfunction ◽  
Behavioral Indices

Neural substrate and underlying mechanisms of working memory: insights from brain stimulation studies

2021 ◽  
Author(s):  
Zakia Z Haque ◽  
Ranshikha Samandra ◽  
Farshad Alizadeh Mansouri
Keyword(s):  
Working Memory ◽  
Brain Stimulation ◽  
Cognitive Functions ◽  
Cognitive Abilities ◽  
Relevant Information ◽  
Brain Regions ◽  
Electrophysiological Recording ◽  
Great Opportunity ◽  
Neural Substrate ◽  
Underlying Mechanisms

The concept of working memory refers to a collection of cognitive abilities and processes involved in the short-term storage of task-relevant information to guide the ongoing and upcoming behaviour and therefore describes an important aspect of executive control of behaviour for achieving goals. Deficits in working memory and related cognitive abilities have been observed in patients with brain damage or neuropsychological disorders and therefore it is important to better understand neural substrate and underlying mechanisms of working memory. Working memory relies on neural mechanisms that enable encoding, maintenance and manipulation of stored information as well as integrating them with ongoing and future goals. Recently, a surge in brain stimulation studies have led to development of various non-invasive techniques for localized stimulation of prefrontal and other cortical regions in humans. These brain stimulation techniques can potentially be tailored to influence neural activities in particular brain regions and modulate cognitive functions and behaviour. Combined use of brain stimulation with neuroimaging and electrophysiological recording have provided a great opportunity to monitor neural activity in various brain regions and non-invasively intervene and modulate cognitive functions in cognitive tasks. These studies have shed more light on the neural substrate and underlying mechanisms of working memory in humans. Here, we review findings and insight from these brain stimulation studies about the contribution of brain regions, and particularly prefrontal cortex, to working memory.

Encoding vs trace decay: Specifying the mechanism underlying auditory working memory dysfunction in schizophrenia

1997 ◽  
Vol 24 (1-2) ◽  
pp. 238
Author(s):  
Anne-Marie Shelley ◽  
Daniel C. Javitt ◽  
Herbert G. Vaughan ◽  
Gail Silipo
Keyword(s):  
Working Memory ◽  
Memory Dysfunction

Neurobiological evidence of everyday working memory dysfunction in ptsd using pet and high-density eeg

2000 ◽  
Vol 34 (s1) ◽  
pp. A13-A13
Author(s):  
C R Clark ◽  
A C McFarlane ◽  
P Morris ◽  
G F Egan ◽  
D L Weber ◽  
...  
Keyword(s):  
Working Memory ◽  
High Density ◽  
Memory Dysfunction

scholarly journals Contribution of Impaired Early-Stage Visual Processing to Working Memory Dysfunction in Adolescents With Schizophrenia

2007 ◽  
Vol 64 (11) ◽  
pp. 1229 ◽  
Author(s):  
Corinna Haenschel ◽  
Robert A. Bittner ◽  
Fabian Haertling ◽  
Anna Rotarska-Jagiela ◽  
Konrad Maurer ◽  
...  
Keyword(s):  
Working Memory ◽  
Visual Processing ◽  
Early Stage ◽  
Memory Dysfunction

scholarly journals Persistent working memory dysfunction following traumatic brain injury: Evidence for a time-dependent mechanism

Neuroscience ◽  
2009 ◽  
Vol 159 (2) ◽  
pp. 483-491 ◽  
Author(s):  
M.M. Hoskison ◽  
A.N. Moore ◽  
B. Hu ◽  
S. Orsi ◽  
N. Kobori ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Working Memory ◽  
Brain Injury ◽  
Time Dependent ◽  
Memory Dysfunction ◽  
Dependent Mechanism

Behavioural studies of spatial working memory dysfunction in schizophrenia: A quantitative literature review

2007 ◽  
Vol 150 (2) ◽  
pp. 111-121 ◽  
Author(s):  
Danijela Piskulic ◽  
James S. Olver ◽  
Trevor R. Norman ◽  
Paul Maruff
Keyword(s):  
Working Memory ◽  
Literature Review ◽  
Spatial Working Memory ◽  
Memory Dysfunction

Mechanisms of Working Memory Dysfunction after Mild and Moderate TBI: Evidence from Functional MRI and Neurogenetics

2006 ◽  
Vol 23 (10) ◽  
pp. 1450-1467 ◽  
Author(s):  
Thomas W. McAllister ◽  
Laura A. Flashman ◽  
Brenna C. McDonald ◽  
Andrew J. Saykin
Keyword(s):  
Working Memory ◽  
Functional Mri ◽  
Memory Dysfunction

scholarly journals Olfactory Examination in Korsakoff's Syndrome: Implications for Early Diagnosis

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Dawn E. Jones ◽  
Marie Rowland ◽  
R. Martyn Bracewell
Keyword(s):  
Working Memory ◽  
Olfactory Function ◽  
Memory Dysfunction ◽  
Korsakoff’S Syndrome ◽  
Memory Impairments ◽  
Benton Visual Retention Test ◽  
Healthy Control ◽  
Korsakoff's Syndrome ◽  
With Memory ◽  
Smell Identification

Whilst olfactory dysfunction has been reported in Korsakoff's Syndrome (KS) patients, the diagnostic implications of this have not been fully explored. KS can be difficult to diagnose because cognitive symptoms are similar to other diagnoses. For instance, patients with Frontal Lobe (FL) Syndrome may present with memory impairments that are similar to KS. Participants were given the Benton Visual Retention Test-Fifth Edition (BVRT-V), to identify working memory dysfunction, and a Brief Smell Identification Test (B-SIT), to evaluate olfactory function. B-SIT scores were found to be significantly lower in the KS group compared to the control and FL groups. In contrast, the error scores on the BVRT-V were significantly higher in both the KS and FL groups compared to the healthy control subjects. Therefore, we suggest that olfactory function may aid in the differential diagnosis of patients presenting with working memory dysfunction.

Sign in / Sign up

Export Citation Format

Share Document