scholarly journals Disease modification in partial epilepsy

Brain ◽  
2002 ◽  
Vol 125 (9) ◽  
pp. 1937-1950 ◽  
Author(s):  
M. C. Walker
Keyword(s):  
Partial Epilepsy ◽  
Disease Modification

Factors associated with relapse after antiepileptic drug withdrawal in a selected population with partial epilepsy

1999 ◽  
Vol 41 (9) ◽  
pp. 643-645 ◽  
Author(s):  
Alberto Verrotti ◽  
Simonetta Morresi ◽  
Rocco Cutarella ◽  
Guido Morgese ◽  
Francesco Chiarelli
Keyword(s):  
Antiepileptic Drug ◽  
Drug Withdrawal ◽  
Partial Epilepsy ◽  
Factors Associated ◽  
Antiepileptic Drug Withdrawal

Vergleich von Blutfluß und Benzodiazepin-Rezeptorverteilung bei fokaler Epilepsie: Vorläufige Ergebnisse einer SPECT-Studie

1989 ◽  
Vol 28 (05) ◽  
pp. 181-186
Author(s):  
A. Ludolph ◽  
O. Schober ◽  
G. Lottes ◽  
I. Böttger ◽  
H.-F. Beer ◽  
...  
Keyword(s):  
Human Brain ◽  
Receptor Binding ◽  
Brain Area ◽  
Brain Perfusion ◽  
Partial Epilepsy ◽  
Cerebral Lesion ◽  
Receptor Ligand ◽  
Receptor Mapping ◽  
Hmpao Spect ◽  
99Mtc Hmpao

99mTc-HMPAO-SPECT and SPECT with the 123I-labelled benzodiazepine (Bz) receptor ligand Ro 16-0154 were performed in 10 patients suffering from partial epilepsy, without cerebral lesion in MRT or CT. 2 h p.i. of Ro 16-0154 the distribution of activity correlated with the known distribution of Bz- receptors in the human brain. Perfusion and receptor-binding were found decreased in 7 patients of each study in the suspicious brain-area. 123l-labelled Ro 16-0154 is suitable for Bz-receptor mapping by SPECT. The decrease of Bz-receptor binding in epileptic foci, as described in PET-studies, was also detected by SPECT in 7 of 10 patients.

Magnetic resonance imaging findings and its association to electroencephalogram in children with partial epilepsy (Preprint)

2020 ◽  
Author(s):  
Huynh Quang Huy
Keyword(s):  
Magnetic Resonance Imaging ◽  
Preschool Children ◽  
Magnetic Resonance ◽  
Brain Mri ◽  
Partial Epilepsy ◽  
Small Sample ◽  
Normal Brain ◽  
Resonance Imaging ◽  
Normal Children ◽  
Eeg Abnormalities

BACKGROUND It is important to identify the neuroimaging features that are associated with partial epilepsy in preschool children. Advances in technology recently to localize focal epileptogenic lesions, especially that of high-resolution structural imaging with magnetic resonance imaging (MRI). The recommendation that electroencephalography (EEG) should be gold criteria and that M.R.I should be optional has been questioned. OBJECTIVE The present study aims to to explore the brain lesions on MRI and its association to electroencephalogram in children with partial epilepsy. METHODS The present study was conducted among 112 preschool children with history of partial seizures. All patients underwent EEG and brain MRI. The epileptogenic lesions were identified on the basis of the signal intensities and morphological abnormalities seen on MRI. The correlation between MRI and EEG abnormalities was explored using a chi-square test. RESULTS Abnormal MRI were found in 34.8% (n = 39) of the sample. The EEG and MRI agreed with respect to classify into abnormal or normal in 48.2% (n = 54). Of the 27 patients with a normal EEG, six (22.2%) were seen to have an abnormal MRI. CONCLUSIONS A number of MRI abnormalities was found in our study of otherwise normal children, although the correlation between these results was not clear. Follow-up of these children will help us identify the important abnormalities. Despite of small sample, our results showed that a normal E.E.G findings does not predict a normal brain MRI in children with partial epilepsy.

scholarly journals The Role of Statins in Disease Modification and Cardiovascular Risk in Rheumatoid Arthritis

2018 ◽  
Vol 5 ◽  
Author(s):  
Stergios Soulaidopoulos ◽  
Elena Nikiphorou ◽  
Theodoros Dimitroulas ◽  
George D. Kitas
Keyword(s):  
Rheumatoid Arthritis ◽  
Cardiovascular Risk ◽  
Disease Modification
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