scholarly journals Generation of symptomatic palatal tremor is not correlated with inferior olivary hypertrophy

Brain ◽  
2002 ◽  
Vol 125 (6) ◽  
pp. 1348-1357 ◽  
Author(s):  
Makoto Nishie ◽  
Yasuji Yoshida ◽  
Yutaka Hirata ◽  
Muneo Matsunaga
2020 ◽  
Vol 7 (S3) ◽  
Author(s):  
Deepak K. Gupta ◽  
Angel Viñuela ◽  
Peter H.R. Green ◽  
Michael J. Pitman ◽  
Jean P. Vonsattel ◽  
...  

2016 ◽  
Vol 7 (2) ◽  
pp. NP5-NP6 ◽  
Author(s):  
Joseph Zachariah ◽  
Sunil Manjila

2003 ◽  
Vol 61 (2B) ◽  
pp. 473-477 ◽  
Author(s):  
Carlos R.M. Rieder ◽  
Ricardo Gurgel Rebouças ◽  
Marcelo Paglioli Ferreira

Hypertrophic olivary degeneration (HOD) is a rare type of neuronal degeneration involving the dento-rubro-olivary pathway and presents clinically as palatal tremor. We present a 48 year old male patient who developed Holmes' tremor and bilateral HOD five months after brainstem hemorrhage. The severe rest tremor was refractory to pharmacotherapy and botulinum toxin injections, but was markedly reduced after thalamotomy. Magnetic resonance imaging permitted visualization of HOD, which appeared as a characteristic high signal intensity in the inferior olivary nuclei on T2- and proton-density-weighted images. Enlargement of the inferior olivary nuclei was also noted. Palatal tremor was absent in that moment and appears about two months later. The delayed-onset between insult and tremor following structural lesions of the brain suggest that compensatory or secondary changes in nervous system function must contribute to tremor genesis. The literature and imaging findings of this uncommon condition are reviewed.


Neurology ◽  
2006 ◽  
Vol 67 (7) ◽  
pp. 1250-1250 ◽  
Author(s):  
A. J. Espay ◽  
F. J. Revilla

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Fadil Khoyratty ◽  
Thomas Wilson

Symptomatic palatal tremor is potentially the result of a lesion in the triangle of Guillain-Mollaret (1931) and is associated with hypertrophic olivary degeneration (HOD) which has characteristic MR findings. The triangle is defined by dentate efferents ascending through the superior cerebellar peduncle and crossing in the decussation of the brachium conjunctivum inferior to the red nucleus, to finaliy reach the inferior olivary nucleus (ION) via the central tegmental tract. The triangle is completed by ION decussating efferents terminating on the original dentate nucleus via the inferior cerebellar peduncle. We can demonstrate the anatomy of this anatomical triangle using a clinical case of palatal tremor presenting with bilateral subjective pulsatile tinnitus along with the pathognomonic MR findings previously described. The hyperintense T2 signal in these patients may be permanent, but the hypertrophied olive normally regresses after 4 years. The temporal relationship between the evolution of the histopathology and the development of the palatal tremor remains unknown as does the natural history of the tremor. Botox injection at the level of tensor and levator veli palatini insertion have been used to treat patients with disabling tremor synchronous tinnitus. A lesion involving the triangle can have a quite varied clinical expression.


2014 ◽  
Vol 23 (3) ◽  
pp. 554-556 ◽  
Author(s):  
Yasuteru Inoue ◽  
Fumio Miyashita ◽  
Masatoshi Koga ◽  
Naoaki Yamada ◽  
Kazunori Toyoda ◽  
...  

2019 ◽  
Vol 40 (2) ◽  
pp. 191-195 ◽  
Author(s):  
Makoto Hideshima ◽  
Goichi Beck ◽  
Misaki Yamadera ◽  
Yuichi Motoyama ◽  
Kensuke Ikenaka ◽  
...  

2020 ◽  
Vol 40 (1) ◽  
pp. 97-99
Author(s):  
Jae-Myung Kim ◽  
Ji-Yun Park ◽  
Kyung Wook Kang ◽  
Tai-Seung Nam ◽  
Seung-Han Lee

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