scholarly journals Respiratory muscle strength and ventilatory failure in amyotrophic lateral sclerosis

Brain ◽  
2001 ◽  
Vol 124 (10) ◽  
pp. 2000-2013 ◽  
Author(s):  
R. A. Lyall
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Muscle Strength ◽  
Respiratory Muscle ◽  
Respiratory Muscle Strength ◽  
Ventilatory Failure ◽  
Lateral Sclerosis

scholarly journals Assessment and monitoring of ventilatory function and cough efficacy in patients with amyotrophic lateral sclerosis

2016 ◽  
Vol 67 (1) ◽  
Author(s):  
A. Chetta ◽  
M. Aiello ◽  
P. Tzani ◽  
D. Olivieri
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Muscle Strength ◽  
Respiratory Muscle ◽  
Gas Analysis ◽  
Rational Approach ◽  
Strength Testing ◽  
Respiratory Muscle Strength ◽  
Ventilatory Function ◽  
Sleep Study ◽  
Lateral Sclerosis

Assessing and monitoring respiratory muscle function is crucial in patients with Amyotrophic Lateral Sclerosis, since impaired function can lead to either ventilatory failure or respiratory tract infection. Spirometry, diffusing capacity of the lung, breathing pattern, sleep study, blood gas analysis and respiratory muscle strength tests, as well as cough peak flow and cough expiratory volume measurements can provide relevant information on ventilatory function and cough efficacy. With regard to respiratory muscle strength testing, the rational approach consists in starting with volitional and non-invasive tests and later using invasive and non-volitional tests. This review focuses on both ventilatory and respiratory muscle strength testing, in order to undertake a timely treatment of respiratory failure and/or impaired cough efficacy. So far, the current literature has not highlighted any gold standard which stipulates when to commence ventilation and cough support in patients with Amyotrophic Lateral Sclerosis. A composite set of clinical and functional parameters is required for treatment scheduling to monitor lung involvement and follow-up in these patients.

scholarly journals Monitoring respiratory muscle strength assists in early diagnosis of respiratory dysfunction as opposed to the isolated use of pulmonary function evaluation in amyotrophic lateral sclerosis

2013 ◽  
Vol 71 (3) ◽  
pp. 146-152 ◽  
Author(s):  
Guilherme Fregonezi ◽  
Palomma Russelly Saldanha Araújo ◽  
Tathiana Lindemberg Ferreira Macêdo ◽  
Mario Emilio Dourado Junior ◽  
Vanessa Regiane Resqueti ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Muscle Strength ◽  
Early Diagnosis ◽  
Pulmonary Function ◽  
Healthy Subjects ◽  
Respiratory Muscle ◽  
Function Evaluation ◽  
Respiratory Muscle Strength ◽  
Respiratory Dysfunction ◽  
Lateral Sclerosis

ObjectiveIt was study the relationship between respiratory muscle strength and forced vital capacity (FVC) in patients with amyotrophic lateral sclerosis (ALS) versus healthy subjects.MethodsPulmonary function and respiratory muscle strength [maximal inspiratory (PImax), maximal expiratory (PEmax) and sniff nasal inspiratory pressure (SNIP)] were assessed in patients with ALS and healthy subjects, matched using cutoffs established in the literature for impaired pulmonary function and respiratory muscle weakness.ResultsTwenty-eight ALS patients and 28 healthy subjects were studied. We found sensitivity and specificity for PImax, PEmax and SNIP of 75/58%, 81/67% and 75/67%. The Receiver Operating Characteristic curve (ROC curve) indicated that the variables PImax, PEmax and SNIP can identify differences in respiratory muscle strength between ALS and healthy individuals at 0.89, 0.9 and 0.82, respectively. A positive correlation was recorded between FVC (%) versus SNIP, PImax and PEmax.ConclusionIn ALS, monitoring respiratory muscle strength assists in early diagnosis of respiratory dysfunction as opposed to the isolated use of FVC.

Lung function and respiratory muscle strength in amyotrophic lateral sclerosis

2015 ◽  
Author(s):  
Astrid Sandnes ◽  
Tiina Andersen ◽  
Maria Vollsæter ◽  
Ove Fondenes ◽  
Ola Røksund ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Muscle Strength ◽  
Lung Function ◽  
Respiratory Muscle ◽  
Respiratory Muscle Strength ◽  
Lateral Sclerosis

Poster 15 Characterize Respiratory Muscle Strength and Peak Expiratory Flow in Patients With Amyotrophic Lateral Sclerosis

2013 ◽  
Vol 94 (10) ◽  
pp. e16
Author(s):  
Márcia Midori Morimoto ◽  
Jéssica Santoro ◽  
Elton Gonçalves ◽  
Ruy Camargo Pires Neto ◽  
Mário Caxambu Neto ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Muscle Strength ◽  
Peak Expiratory Flow ◽  
Respiratory Muscle ◽  
Respiratory Muscle Strength ◽  
Expiratory Flow ◽  
Lateral Sclerosis
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