PERIVENTRICULAR LESIONS IN THE WHITE MATTER ON MAGNETIC RESONANCE IMAGING IN THE ELDERLY

Brain ◽  
1991 ◽  
Vol 114 (2) ◽  
pp. 761-774 ◽  
Author(s):  
J. C. VAN SWIETEN ◽  
J. H. W. VAN DEN HOUT ◽  
B. A. VAN KETEL ◽  
A. HIJDRA ◽  
J. H. J. WOKKE ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
The Elderly ◽  
Resonance Imaging ◽  
Periventricular Lesions

scholarly journals Antidepressant Treatment and Worsening White Matter on Serial Cranial Magnetic Resonance Imaging in the Elderly

Stroke ◽  
2008 ◽  
Vol 39 (3) ◽  
pp. 857-862 ◽  
Author(s):  
David C. Steffens ◽  
Hyoju Chung ◽  
K. Ranga R. Krishnan ◽  
W.T. Longstreth ◽  
Michelle Carlson ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
Antidepressant Treatment ◽  
The Elderly ◽  
Resonance Imaging ◽  
Cranial Magnetic Resonance Imaging

scholarly journals Incidence, Manifestations, and Predictors of Worsening White Matter on Serial Cranial Magnetic Resonance Imaging in the Elderly

Stroke ◽  
2005 ◽  
Vol 36 (1) ◽  
pp. 56-61 ◽  
Author(s):  
W.T. Longstreth ◽  
Alice M. Arnold ◽  
Norman J. Beauchamp ◽  
Teri A. Manolio ◽  
David Lefkowitz ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
The Elderly ◽  
Resonance Imaging ◽  
Cranial Magnetic Resonance Imaging

Late presentation of NMOSD as rapidly progressive leukoencephalopathy with atypical clinical and radiological findings

2017 ◽  
Vol 24 (5) ◽  
pp. 685-688 ◽  
Author(s):  
Elia Sechi ◽  
Alberto Addis ◽  
Lucia Batzu ◽  
Sara Mariotto ◽  
Sergio Ferrari ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
The Elderly ◽  
Late Presentation ◽  
Neuromyelitis Optica Spectrum Disorder ◽  
Resonance Imaging ◽  
Radiological Findings ◽  
Mri Findings ◽  
Magnetic Resonance Imaging Mri

Brain abnormalities in neuromyelitis optica spectrum disorder (NMOSD) are highly heterogeneous and often non-specific. Extensive white matter involvement has been described and frequently manifests with encephalopathy requiring prompt intervention. Rarely, this may represent the only manifestation at onset without concurrent suggestive features of the disease, thus making diagnosis challenging. NMOSD may potentially occur at any age, but it seems that this disorder has distinctive clinical features in the elderly. We describe a case of NMOSD presenting as rapidly progressive leukoencephalopathy with atypical clinical and magnetic resonance imaging (MRI) findings in a 69-year-old woman.

scholarly journals Risk factors for white matter changes detected by magnetic resonance imaging in the elderly.

Stroke ◽  
1990 ◽  
Vol 21 (10) ◽  
pp. 1424-1428 ◽  
Author(s):  
P Sullivan ◽  
R Pary ◽  
F Telang ◽  
A H Rifai ◽  
G S Zubenko
Keyword(s):  
Magnetic Resonance Imaging ◽  
Risk Factors ◽  
White Matter ◽  
Magnetic Resonance ◽  
The Elderly ◽  
Resonance Imaging ◽  
White Matter Changes

scholarly journals Magnetic resonance imaging findings in children with Parry-Romberg syndrome and en coup de sabre

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Harry Knights ◽  
Elizabeth Minas ◽  
Faraan Khan ◽  
Lindsay Shaw ◽  
Muthana Al Obaidi ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
Brain Imaging ◽  
Case Series ◽  
Dystrophic Calcification ◽  
Resonance Imaging ◽  
Cutaneous Manifestations ◽  
Street Hospital ◽  
Parry Romberg Syndrome

Abstract Background The aim of this study was to: (i) describe the abnormalities seen on brain imaging in a group of children with en coup de sabre (EDCS) with/without Parry-Romberg syndrome (PRS); and (ii) identify clinical predictors of brain imaging abnormalities. Methods This was a single centre (Great Ormond Street Hospital, London) retrospective case series of patients with ECDS/PRS seen from 2000 to 2018. We identified patients with cutaneous manifestations consistent with the clinical descriptions of ECDS/PRS. Presenting clinical, laboratory, and radiological brain findings are described. Results are expressed as medians and ranges or frequencies and percentages. Fisher’s exact test was used to identify clinical associations with magnetic resonance imaging (MRI) abnormalities. Results Fourteen patients were studied: 6 males and 8 females; median age 14 years (range 3–20). We observed neuroimaging abnormalities in 2/6 ECDS and 5/8 ECDS/PRS patients. White matter signal abnormality, dystrophic calcification, leptomeningeal enhancement, and sulcal crowding were the typical findings on brain imaging. A total of 50% of patients had no MRI abnormality despite some of these patients having neurological symptoms. The presence of seizures was significantly associated with ipsilateral enhanced white matter signalling on MRI (p < 0.05). Conclusions In summary, we observed several distinct radiographic patterns associated with ECDS/PRS. Seizure disorder was strongly associated with the presence of ipsilateral enhanced white matter signalling. Improved neuroimaging techniques that combine morphological with functional imaging may improve the detection rate of brain involvement in children with ECDS/PRS in the future.

scholarly journals ASPREE-NEURO study protocol: A randomized controlled trial to determine the effect of low-dose aspirin on cerebral microbleeds, white matter hyperintensities, cognition, and stroke in the healthy elderly

2016 ◽  
Vol 12 (1) ◽  
pp. 108-113 ◽  
Author(s):  
Stephanie A Ward ◽  
Parnesh Raniga ◽  
Nicholas J Ferris ◽  
Robyn L Woods ◽  
Elsdon Storey ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Primary Prevention ◽  
Magnetic Resonance ◽  
Controlled Trial ◽  
Brain Magnetic Resonance Imaging ◽  
Cerebral Microbleeds ◽  
Resonance Imaging ◽  
Healthy Elderly ◽  
Cerebral Microbleed

Rationale Cerebral microbleeds seen on brain magnetic resonance imaging are markers of small vessel disease, linked to cognitive dysfunction and increased ischemic and hemorrhagic stroke risk. Observational studies suggest that aspirin use may induce cerebral microbleeds, and associated overt intracranial hemorrhage, but this has not been definitively resolved. Aims ASPREE-NEURO will determine the effect of aspirin on cerebral microbleed development over three years in healthy adults aged 70 years and over, participating in the larger ‘ASPirin in Reducing Events in the Elderly (ASPREE)’ primary prevention study of aspirin. Sample size Five hundred and fifty-nine participants provide 75% power (two-sided p value of 0.05) to determine an average difference of 0.5 cerebral microbleed per person after three years. Methods and design A multi-center, randomized placebo-controlled trial of 100 mg daily aspirin in participants who have brain magnetic resonance imaging at study entry, one and three years after randomization and who undergo cognitive testing at the same time points. Study outcomes The primary outcome is the number of new cerebral microbleeds on magnetic resonance imaging after three years. Secondary outcomes are the number of new cerebral microbleeds after one year, change in volume of white matter hyperintensity, cognitive function, and stroke. Discussion ASPREE-NEURO will resolve whether aspirin affects the presence and number of cerebral microbleeds, their relationship with cognitive performance, and indicate whether consideration of cerebral microbleeds alters the risk-benefit profile of aspirin in primary prevention for older people. Trial registration Australian New Zealand Clinical Trials Registry ACTRN12613001313729.

Magnetic resonance imaging cinecisternography in patients with white matter lesions

1992 ◽  
Vol 2 (4) ◽  
pp. 213-215
Author(s):  
Yasuo Fukuuchi ◽  
Takahiro Amano ◽  
Hayao Shiga ◽  
Makoto Ichijo ◽  
Yoshiaki Itoh ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
White Matter Lesions ◽  
Resonance Imaging
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