STUDIES ON CEREBRAL OXYGEN METABOLISM, BLOOD FLOW, AND BLOOD VOLUME, IN PATIENTS WITH HYDROCEPHALUS BEFORE AND AFTER SURGICAL DECOMPRESSION, USING POSITRON EMISSION TOMOGRAPHY

Brain ◽  
1986 ◽  
Vol 109 (4) ◽  
pp. 613-628 ◽  
Author(s):  
D. J. BROOKS ◽  
R. P. BEANEY ◽  
M. POWELL ◽  
K. L. LEENDERS ◽  
H. A. CROCKARD ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Blood Flow ◽  
Blood Volume ◽  
Oxygen Metabolism ◽  
Surgical Decompression ◽  
Emission Tomography ◽  
Cerebral Oxygen ◽  
Cerebral Oxygen Metabolism ◽  
Positron Emission ◽  
Before And After

Age-related decline of cerebral oxygen metabolism in normal population detected with positron emission tomography

1992 ◽  
Vol 14 (2) ◽  
pp. 128-131 ◽  
Author(s):  
Hiroto Takada ◽  
Ken Nagata ◽  
Yutaka Hirata ◽  
Yuichi Satoh ◽  
Yasuhito Watahiki ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Normal Population ◽  
Oxygen Metabolism ◽  
Emission Tomography ◽  
Cerebral Oxygen ◽  
Cerebral Oxygen Metabolism ◽  
Age Related ◽  
Positron Emission

Cerebral oxygen metabolism in awake monkeys using positron emission tomography with 15O-gas

NeuroImage ◽  
1998 ◽  
Vol 7 (4) ◽  
pp. S276
Author(s):  
H. Okada ◽  
Y. Ouchi ◽  
E. Yoshikawa ◽  
T. Kakiuchi ◽  
S. Nishiyama ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Oxygen Metabolism ◽  
Emission Tomography ◽  
Cerebral Oxygen ◽  
Cerebral Oxygen Metabolism ◽  
Positron Emission

scholarly journals Effects of Acetazolamide on Cerebral Blood Flow, Blood Volume, and Oxygen Metabolism: A Positron Emission Tomography Study with Healthy Volunteers

2001 ◽  
Vol 21 (12) ◽  
pp. 1472-1479 ◽  
Author(s):  
Hidehiko Okazawa ◽  
Hiroshi Yamauchi ◽  
Kanji Sugimoto ◽  
Hiroshi Toyoda ◽  
Yoshihiko Kishibe ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Metabolic Rate ◽  
Blood Volume ◽  
Cerebral Blood Volume ◽  
Capillary Blood ◽  
Emission Tomography ◽  
Positron Emission ◽  
Capillary Blood Volume

To evaluate changes in cerebral hemodynamics and metabolism induced by acetazolamide in healthy subjects, positron emission tomography studies for measurement of cerebral perfusion and oxygen consumption were performed. Sixteen healthy volunteers underwent positron emission tomography studies with15O-gas and water before and after intravenous administration of acetazolamide. Dynamic positron emission tomography data were acquired after bolus injection of H215O and bolus inhalation of15O2. Cerebral blood flow, metabolic rate of oxygen, and arterial-to-capillary blood volume images were calculated using the three-weighted integral method. The images of cerebral blood volume were calculated using the bolus inhalation technique of C15O. The scans for cerebral blood flow and volume and metabolic rate of oxygen after acetazolamide challenge were performed at 10, 20, and 30 minutes after drug injection. The parametric images obtained under the two conditions at baseline and after acetazolamide administration were compared. The global and regional values for cerebral blood flow and volume and arterial-to-capillary blood volume increased significantly after acetazolamide administration compared with the baseline condition, whereas no difference in metabolic rate of oxygen was observed. Acetazolamide-induced increases in both blood flow and volume in the normal brain occurred as a vasodilatory reaction of functioning vessels. The increase in arterial-to-capillary blood volume made the major contribution to the cerebral blood volume increase, indicating that the raise in cerebral blood flow during the acetazolamide challenge is closely related to arterial-to-capillary vasomotor responsiveness.

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