scholarly journals Non-steroidal anti-inflammatory drugs in the oncological surgical population: beneficial or harmful? A systematic review of the literature

2017 ◽  
Vol 119 (4) ◽  
pp. 750-764 ◽  
Author(s):  
J.P. Cata ◽  
C.E. Guerra ◽  
G.J. Chang ◽  
V. Gottumukkala ◽  
G.P. Joshi
Keyword(s):  
Systematic Review ◽  
Review Of The Literature ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

scholarly journals Non-steroidal anti-inflammatory drugs and risk of venous thromboembolism: a systematic review and meta-analysis

Rheumatology ◽  
2014 ◽  
Vol 54 (4) ◽  
pp. 736-742 ◽  
Author(s):  
Patompong Ungprasert ◽  
Narat Srivali ◽  
Karn Wijarnpreecha ◽  
Prangthip Charoenpong ◽  
Eric L. Knight
Keyword(s):  
Systematic Review ◽  
Venous Thromboembolism ◽  
Meta Analysis ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

scholarly journals Nonsteroidal Anti-Inflammatory Drugs and Their Neuroprotective Role After an Acute Spinal Cord Injury: A Systematic Review of Animal Models

2020 ◽  
pp. 219256822090168
Author(s):  
Mark J. Lambrechts ◽  
James L. Cook
Keyword(s):  
Systematic Review ◽  
Spinal Cord ◽  
Animal Models ◽  
Motor Function ◽  
Spinal Cord Injuries ◽  
Inclusion Criteria ◽  
Improve Motor Function ◽  
Cord Injury ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Study Design: Systematic review. Objective: Spinal cord injuries (SCIs) resulting in motor deficits can be devastating injuries resulting in millions of health care dollars spent per incident. Nonsteroidal anti-inflammatory drugs (NSAIDs) are a potential class of drugs that could improve motor function after an SCI. This systematic review utilizes PRISMA guidelines to evaluate the effectiveness of NSAIDs for SCI. Methods: PubMed/MEDLINE, CINAHL, PsycINFO, Embase, and Scopus were reviewed linking the keywords of “ibuprofen,” “meloxicam,” “naproxen,” “ketorolac,” “indomethacin,” “celecoxib,” “ATB-346,” “NSAID,” and “nonsteroidal anti-inflammatory drug” with “spinal.” Results were reviewed for relevance and included if they met inclusion criteria. The SYRCLE checklist was used to assess sources of bias. Results: A total of 2960 studies were identified in the PubMed/MEDLINE database using the above-mentioned search criteria. A total of 461 abstracts were reviewed in Scopus, 340 in CINAHL, 179 in PsycINFO, and 7632 in Embase. A total of 15 articles met the inclusion criteria. Conclusions: NSAIDs’ effectiveness after SCI is largely determined by its ability to inhibit Rho-A. NSAIDs are a promising therapeutic option in acute SCI patients because they appear to decrease cord edema and inflammation, increase axonal sprouting, and improve motor function with minimal side effects. Studies are limited by heterogeneity, small sample size, and the use of animal models, which might not replicate the therapeutic effects in humans. There are no published human studies evaluating the safety and efficacy of these drugs after a traumatic cord injury. There is a need for well-designed prospective studies evaluating ibuprofen or indomethacin after adult spinal cord injuries.

Do Nonsteroidal Anti-Inflammatory Drugs Have a Deleterious Effect on Cartilage Repair? A Systematic Review

Cartilage ◽  
2019 ◽  
pp. 194760351985577 ◽  
Author(s):  
Gergo Merkely ◽  
Emanuele Chisari ◽  
Claudia Lola Rosso ◽  
Christian Lattermann
Keyword(s):  
Systematic Review ◽  
Cartilage Repair ◽  
Deleterious Effect ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Sa1558 Risk of Non-Steroidal Anti-Inflammatory Drugs-Related Serious Drug-Induced Liver Injury: A Systematic Review and Meta-Analysis

2016 ◽  
Vol 150 (4) ◽  
pp. S1066
Author(s):  
Sakkarin Chirapongsathorn ◽  
Chayakrit Krittanawong ◽  
Ann M. Farrell ◽  
Mohammad H. Murad ◽  
Patrick Kamath
Keyword(s):  
Systematic Review ◽  
Liver Injury ◽  
Meta Analysis ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Anti-Inflammatory Drugs and Risk of Alzheimer's Disease: An Updated Systematic Review and Meta-Analysis

2015 ◽  
Vol 44 (2) ◽  
pp. 385-396 ◽  
Author(s):  
Jun Wang ◽  
Lan Tan ◽  
Hui-Fu Wang ◽  
Chen-Chen Tan ◽  
Xiang-Fei Meng ◽  
...  
Keyword(s):  
Systematic Review ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Meta Analysis ◽  
Inflammatory Drugs ◽  
Anti Inflammatory
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